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Phytochemical Contents and Antioxidant and Antiproliferative Activities of Selected Black and White Sesame Seeds.
Biomed Res Int. 2016; 2016:8495630.BR

Abstract

Sesame (Sesamum indicum L.) seeds are popular nutritional food but with limited knowledge about their antioxidant and antiproliferative activities of various varieties. Phytochemical profiles and antioxidant and antiproliferative activities of six varieties of sesame (Sesamum indicum L.) seeds were studied. Fenheizhi3 (black) cultivar exhibited the maximum contents of total phenolics and lignans and values of total oxygen radical absorbance capacity (ORAC) and antiproliferative activity (EC50) against HepG2 cells. Bound ORAC values showed strong associations with bound phenolics contents (r = 0.976, p < 0.01); in bound phenolic extracts, EC50 values showed strong negative associations with phenolic contents (r = -0.869, p < 0.05) and ORAC values (r = -0.918, p < 0.01). Moreover, the contents of free phenolics were higher than that of the bound phenolics, and the three black sesame seeds generally depicted higher total phenolics compared to the three white varieties. The antioxidant (ORAC values) and antiproliferation activities of six sesame seeds were both associated with contents of bound phenolics (r > 0.8, p < 0.05). Interestingly, nonlignan components in bound phenolics contributed to the antioxidant and antiproliferative activities. This study suggested that Fenheizhi3 variety is superior to the other five varieties as antioxidant supplements.

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Authors+Show Affiliations

Zhou L
Guangdong Province Key Laboratory for Biotechnology Drug Candidates, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou 510006, China; School of Light Industry and Food Sciences, South China University of Technology, Guangzhou 510641, China.
Lin X
School of Light Industry and Food Sciences, South China University of Technology, Guangzhou 510641, China.
Abbasi AM
School of Light Industry and Food Sciences, South China University of Technology, Guangzhou 510641, China; Department of Environmental Sciences, COMSATS Institute of Information Technology, Abbottabad 22060, Pakistan.
Zheng B
School of Light Industry and Food Sciences, South China University of Technology, Guangzhou 510641, China.

MeSH

AntioxidantsCell Line, TumorCell ProliferationHep G2 CellsHumansLignansOxygen Radical Absorbance CapacityPhenolPhytochemicalsPlant ExtractsSeedsSesamum

Pub Type(s)

Journal Article

Language

eng

PubMed ID

27597975

Citation

Zhou, Lin, et al. "Phytochemical Contents and Antioxidant and Antiproliferative Activities of Selected Black and White Sesame Seeds." BioMed Research International, vol. 2016, 2016, p. 8495630.
Zhou L, Lin X, Abbasi AM, et al. Phytochemical Contents and Antioxidant and Antiproliferative Activities of Selected Black and White Sesame Seeds. Biomed Res Int. 2016;2016:8495630.
Zhou, L., Lin, X., Abbasi, A. M., & Zheng, B. (2016). Phytochemical Contents and Antioxidant and Antiproliferative Activities of Selected Black and White Sesame Seeds. BioMed Research International, 2016, 8495630. https://doi.org/10.1155/2016/8495630
Zhou L, et al. Phytochemical Contents and Antioxidant and Antiproliferative Activities of Selected Black and White Sesame Seeds. Biomed Res Int. 2016;2016:8495630. PubMed PMID: 27597975.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Phytochemical Contents and Antioxidant and Antiproliferative Activities of Selected Black and White Sesame Seeds. AU - Zhou,Lin, AU - Lin,Xiaohui, AU - Abbasi,Arshad Mehmood, AU - Zheng,Bisheng, Y1 - 2016/08/14/ PY - 2016/04/15/received PY - 2016/06/07/revised PY - 2016/06/30/accepted PY - 2016/9/7/entrez PY - 2016/9/7/pubmed PY - 2017/2/16/medline SP - 8495630 EP - 8495630 JF - BioMed research international JO - Biomed Res Int VL - 2016 N2 - Sesame (Sesamum indicum L.) seeds are popular nutritional food but with limited knowledge about their antioxidant and antiproliferative activities of various varieties. Phytochemical profiles and antioxidant and antiproliferative activities of six varieties of sesame (Sesamum indicum L.) seeds were studied. Fenheizhi3 (black) cultivar exhibited the maximum contents of total phenolics and lignans and values of total oxygen radical absorbance capacity (ORAC) and antiproliferative activity (EC50) against HepG2 cells. Bound ORAC values showed strong associations with bound phenolics contents (r = 0.976, p < 0.01); in bound phenolic extracts, EC50 values showed strong negative associations with phenolic contents (r = -0.869, p < 0.05) and ORAC values (r = -0.918, p < 0.01). Moreover, the contents of free phenolics were higher than that of the bound phenolics, and the three black sesame seeds generally depicted higher total phenolics compared to the three white varieties. The antioxidant (ORAC values) and antiproliferation activities of six sesame seeds were both associated with contents of bound phenolics (r > 0.8, p < 0.05). Interestingly, nonlignan components in bound phenolics contributed to the antioxidant and antiproliferative activities. This study suggested that Fenheizhi3 variety is superior to the other five varieties as antioxidant supplements. SN - 2314-6141 UR - https://www.unboundmedicine.com/medline/citation/27597975/Phytochemical_Contents_and_Antioxidant_and_Antiproliferative_Activities_of_Selected_Black_and_White_Sesame_Seeds_ DB - PRIME DP - Unbound Medicine ER -