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Sensitive arginine sensing based on inner filter effect of Au nanoparticles on the fluorescence of CdTe quantum dots.
Spectrochim Acta A Mol Biomol Spectrosc. 2017 Feb 15; 173:105-113.SA

Abstract

Arginine plays an important role in many biological functions, whose detection is very significant. Herein, a sensitive, simple and cost-effective fluorescent method for the detection of arginine has been developed based on the inner filter effect (IFE) of citrate-stabilized gold nanoparticles (AuNPs) on the fluorescence of thioglycolic acid-capped CdTe quantum dots (QDs). When citrate-stabilized AuNPs were mixed with thioglycolic acid-capped CdTe QDs, the fluorescence of CdTe QDs was significantly quenched by AuNPs via the IFE. With the presence of arginine, arginine could induce the aggregation and corresponding absorption spectra change of AuNPs, which then IFE-decreased fluorescence could gradually recover with increasing amounts of arginine, achieving fluorescence "turn on" sensing for arginine. The detection mechanism is clearly illustrated and various experimental conditions were also optimized. Under the optimum conditions, a decent linear relationship was obtained in the range from 16 to 121μgL-1 and the limit of detection was 5.6μgL-1. And satisfactory results were achieved in arginine analysis using arginine injection, compound amino acid injection, even blood plasma as samples. Therefore, the present assay showed various merits, such as simplicity, low cost, high sensitivity and selectivity, making it promising for sensing arginine in biological samples.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Liu H
Department of Environmental Science and Engineering, College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193, China.
Li M
Department of Environmental Science and Engineering, College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193, China.
Jiang L
Department of Environmental Science and Engineering, College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193, China.
Shen F
Agro-Environmental Protection Institute, the Ministry of Agriculture, Tianjin 300191, China.
Hu Y
School of Food and Environment, Dalian University of Technology, Panjin 124221, China. Electronic address: yufenghu@dlut.edu.cn.
Ren X
Department of Environmental Science and Engineering, College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193, China. Electronic address: renxueqin@cau.edu.cn.

MeSH

ArginineBiosensing TechniquesCadmium CompoundsFluorescenceGoldHumansHydrogen BondingHydrogen-Ion ConcentrationLimit of DetectionMetal NanoparticlesMicroscopy, Electron, TransmissionQuantum DotsSensitivity and SpecificitySpectrophotometry, UltravioletTelluriumThioglycolates

Pub Type(s)

Journal Article

Language

eng

PubMed ID

27599195

Citation

Liu, Haijian, et al. "Sensitive Arginine Sensing Based On Inner Filter Effect of Au Nanoparticles On the Fluorescence of CdTe Quantum Dots." Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, vol. 173, 2017, pp. 105-113.
Liu H, Li M, Jiang L, et al. Sensitive arginine sensing based on inner filter effect of Au nanoparticles on the fluorescence of CdTe quantum dots. Spectrochim Acta A Mol Biomol Spectrosc. 2017;173:105-113.
Liu, H., Li, M., Jiang, L., Shen, F., Hu, Y., & Ren, X. (2017). Sensitive arginine sensing based on inner filter effect of Au nanoparticles on the fluorescence of CdTe quantum dots. Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 173, 105-113. https://doi.org/10.1016/j.saa.2016.08.057
Liu H, et al. Sensitive Arginine Sensing Based On Inner Filter Effect of Au Nanoparticles On the Fluorescence of CdTe Quantum Dots. Spectrochim Acta A Mol Biomol Spectrosc. 2017 Feb 15;173:105-113. PubMed PMID: 27599195.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sensitive arginine sensing based on inner filter effect of Au nanoparticles on the fluorescence of CdTe quantum dots. AU - Liu,Haijian, AU - Li,Ming, AU - Jiang,Linye, AU - Shen,Feng, AU - Hu,Yufeng, AU - Ren,Xueqin, Y1 - 2016/08/31/ PY - 2016/05/03/received PY - 2016/08/29/revised PY - 2016/08/29/accepted PY - 2016/9/7/pubmed PY - 2018/8/2/medline PY - 2016/9/7/entrez KW - Arginine KW - CdTe quantum dots KW - Fluorescence KW - Gold nanoparticles KW - Inner filter effect SP - 105 EP - 113 JF - Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy JO - Spectrochim Acta A Mol Biomol Spectrosc VL - 173 N2 - Arginine plays an important role in many biological functions, whose detection is very significant. Herein, a sensitive, simple and cost-effective fluorescent method for the detection of arginine has been developed based on the inner filter effect (IFE) of citrate-stabilized gold nanoparticles (AuNPs) on the fluorescence of thioglycolic acid-capped CdTe quantum dots (QDs). When citrate-stabilized AuNPs were mixed with thioglycolic acid-capped CdTe QDs, the fluorescence of CdTe QDs was significantly quenched by AuNPs via the IFE. With the presence of arginine, arginine could induce the aggregation and corresponding absorption spectra change of AuNPs, which then IFE-decreased fluorescence could gradually recover with increasing amounts of arginine, achieving fluorescence "turn on" sensing for arginine. The detection mechanism is clearly illustrated and various experimental conditions were also optimized. Under the optimum conditions, a decent linear relationship was obtained in the range from 16 to 121μgL-1 and the limit of detection was 5.6μgL-1. And satisfactory results were achieved in arginine analysis using arginine injection, compound amino acid injection, even blood plasma as samples. Therefore, the present assay showed various merits, such as simplicity, low cost, high sensitivity and selectivity, making it promising for sensing arginine in biological samples. SN - 1873-3557 UR - https://www.unboundmedicine.com/medline/citation/27599195/Sensitive_arginine_sensing_based_on_inner_filter_effect_of_Au_nanoparticles_on_the_fluorescence_of_CdTe_quantum_dots_ DB - PRIME DP - Unbound Medicine ER -