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Screening for Latent Tuberculosis Infection in Adults: US Preventive Services Task Force Recommendation Statement.
JAMA. 2016 Sep 06; 316(9):962-9.JAMA

Abstract

IMPORTANCE

Tuberculosis remains an important preventable disease in the United States. An effective strategy for reducing the transmission, morbidity, and mortality of active disease is the identification and treatment of latent tuberculosis infection (LTBI) to prevent progression to active disease.

OBJECTIVE

To issue a current US Preventive Services Task Force (USPSTF) recommendation on screening for LTBI.

EVIDENCE REVIEW

The USPSTF reviewed the evidence on screening for LTBI in asymptomatic adults seen in primary care, including evidence dating from the inception of searched databases.

FINDINGS

The USPSTF found adequate evidence that accurate screening tests for LTBI are available, treatment of LTBI provides a moderate health benefit in preventing progression to active disease, and the harms of screening and treatment are small. The USPSTF has moderate certainty that screening for LTBI in persons at increased risk for infection provides a moderate net benefit.

CONCLUSIONS AND RECOMMENDATION

The USPSTF recommends screening for LTBI in populations at increased risk. (B recommendation).

Authors+Show Affiliations

No affiliation info availableUniversity of California, San Francisco.Group Health Research Institute, Seattle, Washington.University of Iowa, Iowa City.University of Wisconsin-Madison.Columbia University, New York, New York.State University of New York Upstate Medical University, Syracuse.Pima County Department of Health, Tucson, Arizona.Independent consultant, Washington, DC.Duke University, Durham, North Carolina.Fairfax Family Practice Residency, Fairfax, Virginia11Virginia Commonwealth University, Richmond.Yale University, New Haven, Connecticut.University of Alabama at Birmingham.University of California, Los Angeles.University of Washington, Seattle.Brown University, Providence, Rhode Island.University of Texas at Austin.

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Comment

Language

eng

PubMed ID

27599331

Citation

US Preventive Services Task Force, et al. "Screening for Latent Tuberculosis Infection in Adults: US Preventive Services Task Force Recommendation Statement." JAMA, vol. 316, no. 9, 2016, pp. 962-9.
US Preventive Services Task Force, Bibbins-Domingo K, Grossman DC, et al. Screening for Latent Tuberculosis Infection in Adults: US Preventive Services Task Force Recommendation Statement. JAMA. 2016;316(9):962-9.
Bibbins-Domingo, K., Grossman, D. C., Curry, S. J., Bauman, L., Davidson, K. W., Epling, J. W., García, F. A., Herzstein, J., Kemper, A. R., Krist, A. H., Kurth, A. E., Landefeld, C. S., Mangione, C. M., Phillips, W. R., Phipps, M. G., & Pignone, M. P. (2016). Screening for Latent Tuberculosis Infection in Adults: US Preventive Services Task Force Recommendation Statement. JAMA, 316(9), 962-9. https://doi.org/10.1001/jama.2016.11046
US Preventive Services Task Force, et al. Screening for Latent Tuberculosis Infection in Adults: US Preventive Services Task Force Recommendation Statement. JAMA. 2016 Sep 6;316(9):962-9. PubMed PMID: 27599331.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Screening for Latent Tuberculosis Infection in Adults: US Preventive Services Task Force Recommendation Statement. AU - ,, AU - Bibbins-Domingo,Kirsten, AU - Grossman,David C, AU - Curry,Susan J, AU - Bauman,Linda, AU - Davidson,Karina W, AU - Epling,John W,Jr AU - García,Francisco A R, AU - Herzstein,Jessica, AU - Kemper,Alex R, AU - Krist,Alex H, AU - Kurth,Ann E, AU - Landefeld,C Seth, AU - Mangione,Carol M, AU - Phillips,William R, AU - Phipps,Maureen G, AU - Pignone,Michael P, PY - 2016/9/7/entrez PY - 2016/9/7/pubmed PY - 2016/9/13/medline SP - 962 EP - 9 JF - JAMA JO - JAMA VL - 316 IS - 9 N2 - IMPORTANCE: Tuberculosis remains an important preventable disease in the United States. An effective strategy for reducing the transmission, morbidity, and mortality of active disease is the identification and treatment of latent tuberculosis infection (LTBI) to prevent progression to active disease. OBJECTIVE: To issue a current US Preventive Services Task Force (USPSTF) recommendation on screening for LTBI. EVIDENCE REVIEW: The USPSTF reviewed the evidence on screening for LTBI in asymptomatic adults seen in primary care, including evidence dating from the inception of searched databases. FINDINGS: The USPSTF found adequate evidence that accurate screening tests for LTBI are available, treatment of LTBI provides a moderate health benefit in preventing progression to active disease, and the harms of screening and treatment are small. The USPSTF has moderate certainty that screening for LTBI in persons at increased risk for infection provides a moderate net benefit. CONCLUSIONS AND RECOMMENDATION: The USPSTF recommends screening for LTBI in populations at increased risk. (B recommendation). SN - 1538-3598 UR - https://www.unboundmedicine.com/medline/citation/27599331/full_citation L2 - https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2016.11046 DB - PRIME DP - Unbound Medicine ER -