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Diffuse "encephalitic" cerebral toxoplasmosis in AIDS. Report of four cases.
J Neurol 1989; 236(5):273-7JN

Abstract

Four patients with AIDS presented with a rapidly fatal global neurological illness. CT did not show any focal lesion and gross post mortem examination of the brain was normal in three of the four cases. Microscopic examination revealed numerous widespread microglial nodules in the brain parenchyma, most containing central toxoplama cysts or free tachyzoites. Such diffuse, non-necrotic, "encephalitic" forms of cerebral toxoplasmosis appear unique to AIDS and, to our knowledge, have not been documented previously. They represent a treatable, often misdiagnosed cause of diffuse neurological involvement in AIDS patients.

Authors+Show Affiliations

Département de Pathologie (Neuropathologie), Hôpital Henri Mondor, Créteil, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

2760644

Citation

Gray, F, et al. "Diffuse "encephalitic" Cerebral Toxoplasmosis in AIDS. Report of Four Cases." Journal of Neurology, vol. 236, no. 5, 1989, pp. 273-7.
Gray F, Gherardi R, Wingate E, et al. Diffuse "encephalitic" cerebral toxoplasmosis in AIDS. Report of four cases. J Neurol. 1989;236(5):273-7.
Gray, F., Gherardi, R., Wingate, E., Wingate, J., Fénelon, G., Gaston, A., ... Poirier, J. (1989). Diffuse "encephalitic" cerebral toxoplasmosis in AIDS. Report of four cases. Journal of Neurology, 236(5), pp. 273-7.
Gray F, et al. Diffuse "encephalitic" Cerebral Toxoplasmosis in AIDS. Report of Four Cases. J Neurol. 1989;236(5):273-7. PubMed PMID: 2760644.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diffuse "encephalitic" cerebral toxoplasmosis in AIDS. Report of four cases. AU - Gray,F, AU - Gherardi,R, AU - Wingate,E, AU - Wingate,J, AU - Fénelon,G, AU - Gaston,A, AU - Sobel,A, AU - Poirier,J, PY - 1989/7/1/pubmed PY - 1989/7/1/medline PY - 1989/7/1/entrez SP - 273 EP - 7 JF - Journal of neurology JO - J. Neurol. VL - 236 IS - 5 N2 - Four patients with AIDS presented with a rapidly fatal global neurological illness. CT did not show any focal lesion and gross post mortem examination of the brain was normal in three of the four cases. Microscopic examination revealed numerous widespread microglial nodules in the brain parenchyma, most containing central toxoplama cysts or free tachyzoites. Such diffuse, non-necrotic, "encephalitic" forms of cerebral toxoplasmosis appear unique to AIDS and, to our knowledge, have not been documented previously. They represent a treatable, often misdiagnosed cause of diffuse neurological involvement in AIDS patients. SN - 0340-5354 UR - https://www.unboundmedicine.com/medline/citation/2760644/Diffuse_ L2 - http://www.diseaseinfosearch.org/result/279 DB - PRIME DP - Unbound Medicine ER -