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Intrasellar and Suprasellar Schwannoma Misdiagnosed as Pituitary Macroadenoma: A Case Report and Review of the Literature.
World Neurosurg. 2016 Dec; 96:612.e1-612.e7.WN

Abstract

BACKGROUND

Intracranial schwannomas usually arise from sensory nerves with a predilection for the trigeminal nerve and the vestibular component of the eighth cranial nerve (VIII). Schwannoma arising in the sella and extending into the suprasellar region is exceedingly rare and easily misdiagnosed as pituitary macroadenoma. Only 26 cases of intrasellar schwannomas have been reported in the literature.

CASE DESCRIPTION

A patient with an intrasellar schwannoma and suprasellar extension was presurgically diagnosed as having pituitary macroadenoma. Subtotal excision of the lesion was performed via an endoscopic endonasal transsphenoidal approach. Histopathology showed schwannoma. His symptoms improved after surgery. Magnetic resonance imaging 6 months after surgery showed a remnant schwannoma in the sella.

CONCLUSIONS

Although schwannoma in the sellar region is rare, it remains an important differential diagnosis because of different surgical approaches.

Authors+Show Affiliations

Department of Neurosurgery, Qilu Hospital of Shandong University, Jinan, Shandong Province, People's Republic of China; Brain Science Research Institute, Shandong University, Jinan, Shandong Province, People's Republic of China.Department of Neurosurgery, Qilu Hospital of Shandong University, Jinan, Shandong Province, People's Republic of China; Department of Neurosurgery, Dezhou People's Hospital, Dezhou, Shandong Province, People's Republic of China.Department of Neurosurgery, Qilu Hospital of Shandong University, Jinan, Shandong Province, People's Republic of China.Department of Neurosurgery, Qilu Hospital of Shandong University, Jinan, Shandong Province, People's Republic of China.Department of Neurosurgery, Qilu Hospital of Shandong University, Jinan, Shandong Province, People's Republic of China. Electronic address: jiadeze@163.com.Department of Neurosurgery, Qilu Hospital of Shandong University, Jinan, Shandong Province, People's Republic of China; Brain Science Research Institute, Shandong University, Jinan, Shandong Province, People's Republic of China. Electronic address: ligangqiluhospital@163.com.

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

27613496

Citation

Zhang, Jinsen, et al. "Intrasellar and Suprasellar Schwannoma Misdiagnosed as Pituitary Macroadenoma: a Case Report and Review of the Literature." World Neurosurgery, vol. 96, 2016, pp. 612.e1-612.e7.
Zhang J, Xu S, Liu Q, et al. Intrasellar and Suprasellar Schwannoma Misdiagnosed as Pituitary Macroadenoma: A Case Report and Review of the Literature. World Neurosurg. 2016;96:612.e1-612.e7.
Zhang, J., Xu, S., Liu, Q., Li, X., Jia, D., & Li, G. (2016). Intrasellar and Suprasellar Schwannoma Misdiagnosed as Pituitary Macroadenoma: A Case Report and Review of the Literature. World Neurosurgery, 96, e1-e7. https://doi.org/10.1016/j.wneu.2016.08.128
Zhang J, et al. Intrasellar and Suprasellar Schwannoma Misdiagnosed as Pituitary Macroadenoma: a Case Report and Review of the Literature. World Neurosurg. 2016;96:612.e1-612.e7. PubMed PMID: 27613496.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Intrasellar and Suprasellar Schwannoma Misdiagnosed as Pituitary Macroadenoma: A Case Report and Review of the Literature. AU - Zhang,Jinsen, AU - Xu,Shugang, AU - Liu,Qinglin, AU - Li,Xueen, AU - Jia,Deze, AU - Li,Gang, Y1 - 2016/09/06/ PY - 2016/06/28/received PY - 2016/08/27/revised PY - 2016/08/30/accepted PY - 2016/9/11/pubmed PY - 2017/9/19/medline PY - 2016/9/11/entrez KW - Endoscopic KW - Intrasellar KW - Schwannoma KW - Suprasellar KW - Transsphenoidal approach SP - 612.e1 EP - 612.e7 JF - World neurosurgery JO - World Neurosurg VL - 96 N2 - BACKGROUND: Intracranial schwannomas usually arise from sensory nerves with a predilection for the trigeminal nerve and the vestibular component of the eighth cranial nerve (VIII). Schwannoma arising in the sella and extending into the suprasellar region is exceedingly rare and easily misdiagnosed as pituitary macroadenoma. Only 26 cases of intrasellar schwannomas have been reported in the literature. CASE DESCRIPTION: A patient with an intrasellar schwannoma and suprasellar extension was presurgically diagnosed as having pituitary macroadenoma. Subtotal excision of the lesion was performed via an endoscopic endonasal transsphenoidal approach. Histopathology showed schwannoma. His symptoms improved after surgery. Magnetic resonance imaging 6 months after surgery showed a remnant schwannoma in the sella. CONCLUSIONS: Although schwannoma in the sellar region is rare, it remains an important differential diagnosis because of different surgical approaches. SN - 1878-8769 UR - https://www.unboundmedicine.com/medline/citation/27613496/Intrasellar_and_Suprasellar_Schwannoma_Misdiagnosed_as_Pituitary_Macroadenoma:_A_Case_Report_and_Review_of_the_Literature_ DB - PRIME DP - Unbound Medicine ER -