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Phototherapy for atopic dermatitis.
Clin Dermatol. 2016 Sep-Oct; 34(5):607-13.CD

Abstract

Phototherapy is a second-line treatment for moderate to severe atopic dermatitis (AD) that effectively decreases cutaneous inflammation with minimal or no systemic side effects. Children in grade school, adolescents, and adults may benefit from phototherapy, when they have chronic AD refractory to first-line topical treatments. This review focuses on six approaches for phototherapy in AD: (1) broadband ultraviolet B (UVB), (2) Goeckerman regimen (coal tar + broadband UVB), (3) narrowband UVB, (4) excimer lasers for targeted areas, (5) combination UVA/UVB, and (6) UVA-1. Phototherapy can be very effective in some individuals, but it is limited by inconvenience and adverse effects, including limited access to in-office treatment, difficulty adhering to thrice-weekly schedule, flaring from excessive heat, and increased risk of skin cancer. Dosing regimen and treatment concerns are reviewed.

Authors+Show Affiliations

Departments of Dermatology, Preventive Medicine, and Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL.Departments of Dermatology, Preventive Medicine, and Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL; Northwestern Medicine Multidisciplinary Eczema Center, Chicago, IL.Department of Dermatology, Mt. Sinai St. Luke's-Roosevelt and Beth Israel Medical Centers, New York, NY. Electronic address: nsilverb@chpnet.org.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

27638440

Citation

Rodenbeck, Dorothy L., et al. "Phototherapy for Atopic Dermatitis." Clinics in Dermatology, vol. 34, no. 5, 2016, pp. 607-13.
Rodenbeck DL, Silverberg JI, Silverberg NB. Phototherapy for atopic dermatitis. Clin Dermatol. 2016;34(5):607-13.
Rodenbeck, D. L., Silverberg, J. I., & Silverberg, N. B. (2016). Phototherapy for atopic dermatitis. Clinics in Dermatology, 34(5), 607-13. https://doi.org/10.1016/j.clindermatol.2016.05.011
Rodenbeck DL, Silverberg JI, Silverberg NB. Phototherapy for Atopic Dermatitis. Clin Dermatol. 2016 Sep-Oct;34(5):607-13. PubMed PMID: 27638440.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Phototherapy for atopic dermatitis. AU - Rodenbeck,Dorothy L, AU - Silverberg,Jonathan I, AU - Silverberg,Nanette B, Y1 - 2016/05/20/ PY - 2016/9/18/entrez PY - 2016/9/18/pubmed PY - 2017/5/4/medline SP - 607 EP - 13 JF - Clinics in dermatology JO - Clin. Dermatol. VL - 34 IS - 5 N2 - Phototherapy is a second-line treatment for moderate to severe atopic dermatitis (AD) that effectively decreases cutaneous inflammation with minimal or no systemic side effects. Children in grade school, adolescents, and adults may benefit from phototherapy, when they have chronic AD refractory to first-line topical treatments. This review focuses on six approaches for phototherapy in AD: (1) broadband ultraviolet B (UVB), (2) Goeckerman regimen (coal tar + broadband UVB), (3) narrowband UVB, (4) excimer lasers for targeted areas, (5) combination UVA/UVB, and (6) UVA-1. Phototherapy can be very effective in some individuals, but it is limited by inconvenience and adverse effects, including limited access to in-office treatment, difficulty adhering to thrice-weekly schedule, flaring from excessive heat, and increased risk of skin cancer. Dosing regimen and treatment concerns are reviewed. SN - 1879-1131 UR - https://www.unboundmedicine.com/medline/citation/27638440/Phototherapy_for_atopic_dermatitis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0738-081X(16)30147-X DB - PRIME DP - Unbound Medicine ER -