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Rapid isolation with Sep-Pak C18 cartridges and wide-bore capillary gas chromatography of organophosphate pesticides.
Forensic Sci Int. 1989 Apr-May; 41(1-2):67-72.FS

Abstract

A simple and rapid method for isolation of eleven organophosphate pesticides with Sep-Pak C18 cartridges from human urine and plasma, is presented. The detection of the pesticides was made by wide-bore capillary gas chromatography (GC) with flame ionization detection. The pesticide-containing samples, after mixing with water, were directly applied to the cartridges and eluted with chloroform/isopropanol (9:1). The recoveries with use of the cartridges were excellent for most pesticides. Separation of each pesticide peak from each other and from impurities on the gas chromatograms was also satisfactory with use of non-polar and slightly polar capillary columns. The isolation method with use of the cartridges, together with the wide-bore capillary GC, seems very useful in forensic and environmental chemistry and clinical toxicology.

Authors+Show Affiliations

Department of Legal Medicine, Hamamatsu University School of Medicine, Japan.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2767581

Citation

Liu, J, et al. "Rapid Isolation With Sep-Pak C18 Cartridges and Wide-bore Capillary Gas Chromatography of Organophosphate Pesticides." Forensic Science International, vol. 41, no. 1-2, 1989, pp. 67-72.
Liu J, Suzuki O, Kumazawa T, et al. Rapid isolation with Sep-Pak C18 cartridges and wide-bore capillary gas chromatography of organophosphate pesticides. Forensic Sci Int. 1989;41(1-2):67-72.
Liu, J., Suzuki, O., Kumazawa, T., & Seno, H. (1989). Rapid isolation with Sep-Pak C18 cartridges and wide-bore capillary gas chromatography of organophosphate pesticides. Forensic Science International, 41(1-2), 67-72.
Liu J, et al. Rapid Isolation With Sep-Pak C18 Cartridges and Wide-bore Capillary Gas Chromatography of Organophosphate Pesticides. Forensic Sci Int. 1989 Apr-May;41(1-2):67-72. PubMed PMID: 2767581.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Rapid isolation with Sep-Pak C18 cartridges and wide-bore capillary gas chromatography of organophosphate pesticides. AU - Liu,J, AU - Suzuki,O, AU - Kumazawa,T, AU - Seno,H, PY - 1989/4/1/pubmed PY - 1989/4/1/medline PY - 1989/4/1/entrez SP - 67 EP - 72 JF - Forensic science international JO - Forensic Sci Int VL - 41 IS - 1-2 N2 - A simple and rapid method for isolation of eleven organophosphate pesticides with Sep-Pak C18 cartridges from human urine and plasma, is presented. The detection of the pesticides was made by wide-bore capillary gas chromatography (GC) with flame ionization detection. The pesticide-containing samples, after mixing with water, were directly applied to the cartridges and eluted with chloroform/isopropanol (9:1). The recoveries with use of the cartridges were excellent for most pesticides. Separation of each pesticide peak from each other and from impurities on the gas chromatograms was also satisfactory with use of non-polar and slightly polar capillary columns. The isolation method with use of the cartridges, together with the wide-bore capillary GC, seems very useful in forensic and environmental chemistry and clinical toxicology. SN - 0379-0738 UR - https://www.unboundmedicine.com/medline/citation/2767581/Rapid_isolation_with_Sep_Pak_C18_cartridges_and_wide_bore_capillary_gas_chromatography_of_organophosphate_pesticides_ L2 - https://linkinghub.elsevier.com/retrieve/pii/0379-0738(89)90237-5 DB - PRIME DP - Unbound Medicine ER -