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Agaricus bisporus powder improved cutaneous mucosal and serum immune parameters and up-regulated intestinal cytokines gene expression in common carp (Cyprinus carpio) fingerlings.
Fish Shellfish Immunol. 2016 Nov; 58:380-386.FS

Abstract

The aim of the present study was to investigate immunomodulatory effects of Agaricus bisporus, white bottom mushroom powder (WBMP) on common carp (Cyprinus carpio) fingerlings. Carps were fed on different levels of WBMP (0, 0.5, 1 and 2%) for 8 weeks and at the end of feeding trial, skin mucus immune parameters (total Ig, lysozyme and protease activity), cytokines gene expression (TNF-alpha, IL1b, IL8) in intestine as well as serum non-specific immune parameters (total Ig, lysozyme and ACH50) were measured. The results showed significant dose dependent increase of skin mucus immune parameters in carps fed WBMP (P < 0.05). While, no significant difference was observed between 0.5% WBMP and control group (P > 0.05). In case of serum non-specific immune parameters, except lysozyme activity, other parameters (Ig total and ACH50) were significantly affected by dietary inclusion of WBMP (P < 0.05). Also, evaluation of cytokines gene expression in the intestine of carps revealed remarkable up-regulation of TNF-alpha in fish fed 2% WBMP supplemented diet compared other treatment (P < 0.05). Likewise, IL1b gene expression was significantly increased in 1 and 2% WBMP treatments compared to the 0.5% WBMP and control groups (P < 0.05). IL8 gene expression was not affected by inclusion of WBMP in carp diet (P > 0.05). Furthermore, feeding on WBMP supplemented diet significantly improved growth performance (P < 0.05). These results indicated that WBMP can be considered as a promising immunostimulants in early stage of common carp culture.

Authors+Show Affiliations

Department of Fisheries, Faculty of Fisheries and Environmental Sciences, Gorgan University of Agricultural Sciences and Natural Resources, P.O. BOX: 45165-386, Gorgan, Iran.Department of Fisheries, Faculty of Fisheries and Environmental Sciences, Gorgan University of Agricultural Sciences and Natural Resources, P.O. BOX: 45165-386, Gorgan, Iran. Electronic address: hoseinifar@gau.ac.ir.Department of Fisheries, Faculty of Fisheries and Environmental Sciences, Gorgan University of Agricultural Sciences and Natural Resources, P.O. BOX: 45165-386, Gorgan, Iran.Department of Fisheries, Faculty of Fisheries and Environmental Sciences, Gorgan University of Agricultural Sciences and Natural Resources, P.O. BOX: 45165-386, Gorgan, Iran.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

27678509

Citation

Khodadadian Zou, Hassan, et al. "Agaricus Bisporus Powder Improved Cutaneous Mucosal and Serum Immune Parameters and Up-regulated Intestinal Cytokines Gene Expression in Common Carp (Cyprinus Carpio) Fingerlings." Fish & Shellfish Immunology, vol. 58, 2016, pp. 380-386.
Khodadadian Zou H, Hoseinifar SH, Kolangi Miandare H, et al. Agaricus bisporus powder improved cutaneous mucosal and serum immune parameters and up-regulated intestinal cytokines gene expression in common carp (Cyprinus carpio) fingerlings. Fish Shellfish Immunol. 2016;58:380-386.
Khodadadian Zou, H., Hoseinifar, S. H., Kolangi Miandare, H., & Hajimoradloo, A. (2016). Agaricus bisporus powder improved cutaneous mucosal and serum immune parameters and up-regulated intestinal cytokines gene expression in common carp (Cyprinus carpio) fingerlings. Fish & Shellfish Immunology, 58, 380-386. https://doi.org/10.1016/j.fsi.2016.09.050
Khodadadian Zou H, et al. Agaricus Bisporus Powder Improved Cutaneous Mucosal and Serum Immune Parameters and Up-regulated Intestinal Cytokines Gene Expression in Common Carp (Cyprinus Carpio) Fingerlings. Fish Shellfish Immunol. 2016;58:380-386. PubMed PMID: 27678509.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Agaricus bisporus powder improved cutaneous mucosal and serum immune parameters and up-regulated intestinal cytokines gene expression in common carp (Cyprinus carpio) fingerlings. AU - Khodadadian Zou,Hassan, AU - Hoseinifar,Seyed Hossein, AU - Kolangi Miandare,Hamed, AU - Hajimoradloo,Abdolmajid, Y1 - 2016/09/24/ PY - 2016/07/31/received PY - 2016/09/22/revised PY - 2016/09/23/accepted PY - 2016/10/23/pubmed PY - 2017/3/3/medline PY - 2016/9/29/entrez KW - Common carp KW - Gene expression KW - Mucosal immunity KW - Mushroom KW - Prebiotics SP - 380 EP - 386 JF - Fish & shellfish immunology JO - Fish Shellfish Immunol VL - 58 N2 - The aim of the present study was to investigate immunomodulatory effects of Agaricus bisporus, white bottom mushroom powder (WBMP) on common carp (Cyprinus carpio) fingerlings. Carps were fed on different levels of WBMP (0, 0.5, 1 and 2%) for 8 weeks and at the end of feeding trial, skin mucus immune parameters (total Ig, lysozyme and protease activity), cytokines gene expression (TNF-alpha, IL1b, IL8) in intestine as well as serum non-specific immune parameters (total Ig, lysozyme and ACH50) were measured. The results showed significant dose dependent increase of skin mucus immune parameters in carps fed WBMP (P < 0.05). While, no significant difference was observed between 0.5% WBMP and control group (P > 0.05). In case of serum non-specific immune parameters, except lysozyme activity, other parameters (Ig total and ACH50) were significantly affected by dietary inclusion of WBMP (P < 0.05). Also, evaluation of cytokines gene expression in the intestine of carps revealed remarkable up-regulation of TNF-alpha in fish fed 2% WBMP supplemented diet compared other treatment (P < 0.05). Likewise, IL1b gene expression was significantly increased in 1 and 2% WBMP treatments compared to the 0.5% WBMP and control groups (P < 0.05). IL8 gene expression was not affected by inclusion of WBMP in carp diet (P > 0.05). Furthermore, feeding on WBMP supplemented diet significantly improved growth performance (P < 0.05). These results indicated that WBMP can be considered as a promising immunostimulants in early stage of common carp culture. SN - 1095-9947 UR - https://www.unboundmedicine.com/medline/citation/27678509/Agaricus_bisporus_powder_improved_cutaneous_mucosal_and_serum_immune_parameters_and_up_regulated_intestinal_cytokines_gene_expression_in_common_carp__Cyprinus_carpio__fingerlings_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1050-4648(16)30615-5 DB - PRIME DP - Unbound Medicine ER -