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Complete Recovery After Acute Zonisamide Overdose in an Adolescent Female.
Pediatr Emerg Care. 2018 Feb; 34(2):e30-e31.PE

Abstract

Zonisamide is a sulfonamide drug used primarily for the treatment of partial seizures in adults. We describe the case of a 15-year-old woman with a mood disorder who survived without complications after ingestion of an estimated 7.5 g of zonisamide. To the best of our knowledge, there are 4 case reports of individuals with intentional ingestion of more than 4 g of zonisamide as a single agent. Our patient developed coma and hypotension 4 hours after ingestion and was treated with a catecholamine infusion, endotracheal intubation, and mechanical ventilation. She had mild electrocardiographic abnormalities and fully recovered after 4 days. This report contributes to the understanding of acute zonisamide poisoning.

Authors

No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

27749631

Citation

McStay, Charlayne, et al. "Complete Recovery After Acute Zonisamide Overdose in an Adolescent Female." Pediatric Emergency Care, vol. 34, no. 2, 2018, pp. e30-e31.
McStay C, Pierce R, Riley C. Complete Recovery After Acute Zonisamide Overdose in an Adolescent Female. Pediatr Emerg Care. 2018;34(2):e30-e31.
McStay, C., Pierce, R., & Riley, C. (2018). Complete Recovery After Acute Zonisamide Overdose in an Adolescent Female. Pediatric Emergency Care, 34(2), e30-e31. https://doi.org/10.1097/PEC.0000000000000854
McStay C, Pierce R, Riley C. Complete Recovery After Acute Zonisamide Overdose in an Adolescent Female. Pediatr Emerg Care. 2018;34(2):e30-e31. PubMed PMID: 27749631.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Complete Recovery After Acute Zonisamide Overdose in an Adolescent Female. AU - McStay,Charlayne, AU - Pierce,Richard, AU - Riley,Carley, PY - 2016/10/18/pubmed PY - 2018/7/6/medline PY - 2016/10/18/entrez SP - e30 EP - e31 JF - Pediatric emergency care JO - Pediatr Emerg Care VL - 34 IS - 2 N2 - Zonisamide is a sulfonamide drug used primarily for the treatment of partial seizures in adults. We describe the case of a 15-year-old woman with a mood disorder who survived without complications after ingestion of an estimated 7.5 g of zonisamide. To the best of our knowledge, there are 4 case reports of individuals with intentional ingestion of more than 4 g of zonisamide as a single agent. Our patient developed coma and hypotension 4 hours after ingestion and was treated with a catecholamine infusion, endotracheal intubation, and mechanical ventilation. She had mild electrocardiographic abnormalities and fully recovered after 4 days. This report contributes to the understanding of acute zonisamide poisoning. SN - 1535-1815 UR - https://www.unboundmedicine.com/medline/citation/27749631/Complete_Recovery_After_Acute_Zonisamide_Overdose_in_an_Adolescent_Female_ L2 - http://dx.doi.org/10.1097/PEC.0000000000000854 DB - PRIME DP - Unbound Medicine ER -