Tags

Type your tag names separated by a space and hit enter

Jejunal varices diagnosed by capsule endoscopy in patients with post-liver transplant portal hypertension.
Pediatr Transplant. 2017 Feb; 21(1)PT

Abstract

Portal hypertension secondary to portal vein obstruction following liver transplant occurs in 5%-10% of children. Jejunal varices are uncommon in this group. We present a case series of children with significant GI blood loss, negative upper endoscopy, and jejunal varices detected by CE. Case series of patients who had CE for chronic GI blood loss following liver transplantation. Three patients who had their initial transplants at a median age of 7 months were identified at our institution presenting at a median age of 8 years (range 7-16 years) with a median Hgb of 2.8 g/dL (range 1.8-6.8 g/dL). Upper endoscopy was negative for significant esophageal varices, gastric varices, and bleeding portal gastropathy in all three children. All three patients had significant jejunal varices noted on CE in mid-jejunum. Jejunal varices were described as large prominent bluish vessels underneath visualized mucosa, one with evidence of recent bleeding. The results led to venoplasty of the portal vein in two patients and a decompressive shunt in one patient with resolution of GI bleed and anemia. CE is useful to diagnose intestinal varices in children with portal hypertension and GI bleeding following liver transplant.

Authors+Show Affiliations

Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.Department of Radiology, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.Department of Surgery, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Pub Type(s)

Case Reports

Language

eng

PubMed ID

27762481

Citation

Bass, Lee M., et al. "Jejunal Varices Diagnosed By Capsule Endoscopy in Patients With Post-liver Transplant Portal Hypertension." Pediatric Transplantation, vol. 21, no. 1, 2017.
Bass LM, Kim S, Superina R, et al. Jejunal varices diagnosed by capsule endoscopy in patients with post-liver transplant portal hypertension. Pediatr Transplant. 2017;21(1).
Bass, L. M., Kim, S., Superina, R., & Mohammad, S. (2017). Jejunal varices diagnosed by capsule endoscopy in patients with post-liver transplant portal hypertension. Pediatric Transplantation, 21(1). https://doi.org/10.1111/petr.12818
Bass LM, et al. Jejunal Varices Diagnosed By Capsule Endoscopy in Patients With Post-liver Transplant Portal Hypertension. Pediatr Transplant. 2017;21(1) PubMed PMID: 27762481.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Jejunal varices diagnosed by capsule endoscopy in patients with post-liver transplant portal hypertension. AU - Bass,Lee M, AU - Kim,Stanley, AU - Superina,Riccardo, AU - Mohammad,Saeed, Y1 - 2016/10/20/ PY - 2016/09/06/accepted PY - 2016/10/21/pubmed PY - 2017/5/19/medline PY - 2016/10/21/entrez KW - GI bleeding KW - capsule endoscopy KW - jejunal varices KW - portal hypertension JF - Pediatric transplantation JO - Pediatr Transplant VL - 21 IS - 1 N2 - Portal hypertension secondary to portal vein obstruction following liver transplant occurs in 5%-10% of children. Jejunal varices are uncommon in this group. We present a case series of children with significant GI blood loss, negative upper endoscopy, and jejunal varices detected by CE. Case series of patients who had CE for chronic GI blood loss following liver transplantation. Three patients who had their initial transplants at a median age of 7 months were identified at our institution presenting at a median age of 8 years (range 7-16 years) with a median Hgb of 2.8 g/dL (range 1.8-6.8 g/dL). Upper endoscopy was negative for significant esophageal varices, gastric varices, and bleeding portal gastropathy in all three children. All three patients had significant jejunal varices noted on CE in mid-jejunum. Jejunal varices were described as large prominent bluish vessels underneath visualized mucosa, one with evidence of recent bleeding. The results led to venoplasty of the portal vein in two patients and a decompressive shunt in one patient with resolution of GI bleed and anemia. CE is useful to diagnose intestinal varices in children with portal hypertension and GI bleeding following liver transplant. SN - 1399-3046 UR - https://www.unboundmedicine.com/medline/citation/27762481/Jejunal_varices_diagnosed_by_capsule_endoscopy_in_patients_with_post_liver_transplant_portal_hypertension_ L2 - https://doi.org/10.1111/petr.12818 DB - PRIME DP - Unbound Medicine ER -