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Official Executive Summary of an American Thoracic Society/American College of Chest Physicians Clinical Practice Guideline: Liberation from Mechanical Ventilation in Critically Ill Adults.
Am J Respir Crit Care Med 2017; 195(1):115-119AJ

Abstract

BACKGROUND

This clinical practice guideline addresses six questions related to liberation from mechanical ventilation in critically ill adults. It is the result of a collaborative effort between the American Thoracic Society and the American College of Chest Physicians.

METHODS

A multidisciplinary panel posed six clinical questions in a Population, Intervention, Comparator, and Outcomes format. A comprehensive literature search and evidence synthesis was performed for each question, which included appraising the certainty in the evidence (i.e., the quality of evidence) using the Grading of Recommendations, Assessment, Development, and Evaluation approach. The Evidence-to-Decision framework was applied to each question, requiring the panel to evaluate and weigh the importance of the problem, the confidence in the evidence, the certainty about how much the public values the main outcomes, the magnitude and balance of desirable and undesirable outcomes, the resources and costs associated with the intervention, the impact on health disparities, and the acceptability and feasibility of the intervention.

RESULTS

Evidence-based recommendations were formulated and graded initially by subcommittees and then modified after full-panel discussions. The recommendations were confirmed by confidential electronic voting; approval required that at least 80% of the panel members agree with the recommendation.

CONCLUSIONS

The panel provides recommendations regarding liberation from mechanical ventilation. The details regarding the evidence and rationale for each recommendation are presented in the American Journal of Respiratory and Critical Care Medicine and Chest.

Authors

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Pub Type(s)

Journal Article
Practice Guideline

Language

eng

PubMed ID

27762608

Citation

Schmidt, Gregory A., et al. "Official Executive Summary of an American Thoracic Society/American College of Chest Physicians Clinical Practice Guideline: Liberation From Mechanical Ventilation in Critically Ill Adults." American Journal of Respiratory and Critical Care Medicine, vol. 195, no. 1, 2017, pp. 115-119.
Schmidt GA, Girard TD, Kress JP, et al. Official Executive Summary of an American Thoracic Society/American College of Chest Physicians Clinical Practice Guideline: Liberation from Mechanical Ventilation in Critically Ill Adults. Am J Respir Crit Care Med. 2017;195(1):115-119.
Schmidt, G. A., Girard, T. D., Kress, J. P., Morris, P. E., Ouellette, D. R., Alhazzani, W., ... Truwit, J. D. (2017). Official Executive Summary of an American Thoracic Society/American College of Chest Physicians Clinical Practice Guideline: Liberation from Mechanical Ventilation in Critically Ill Adults. American Journal of Respiratory and Critical Care Medicine, 195(1), pp. 115-119. doi:10.1164/rccm.201610-2076ST.
Schmidt GA, et al. Official Executive Summary of an American Thoracic Society/American College of Chest Physicians Clinical Practice Guideline: Liberation From Mechanical Ventilation in Critically Ill Adults. Am J Respir Crit Care Med. 2017 01 1;195(1):115-119. PubMed PMID: 27762608.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Official Executive Summary of an American Thoracic Society/American College of Chest Physicians Clinical Practice Guideline: Liberation from Mechanical Ventilation in Critically Ill Adults. AU - Schmidt,Gregory A, AU - Girard,Timothy D, AU - Kress,John P, AU - Morris,Peter E, AU - Ouellette,Daniel R, AU - Alhazzani,Waleed, AU - Burns,Suzanne M, AU - Epstein,Scott K, AU - Esteban,Andres, AU - Fan,Eddy, AU - Ferrer,Miguel, AU - Fraser,Gilles L, AU - Gong,Michelle Ng, AU - L Hough,Catherine, AU - Mehta,Sangeeta, AU - Nanchal,Rahul, AU - Patel,Sheena, AU - Pawlik,Amy J, AU - Schweickert,William D, AU - Sessler,Curtis N, AU - Strøm,Thomas, AU - Wilson,Kevin C, AU - Truwit,Jonathon D, AU - ,, PY - 2016/11/1/pubmed PY - 2017/7/7/medline PY - 2016/11/1/entrez SP - 115 EP - 119 JF - American journal of respiratory and critical care medicine JO - Am. J. Respir. Crit. Care Med. VL - 195 IS - 1 N2 - BACKGROUND: This clinical practice guideline addresses six questions related to liberation from mechanical ventilation in critically ill adults. It is the result of a collaborative effort between the American Thoracic Society and the American College of Chest Physicians. METHODS: A multidisciplinary panel posed six clinical questions in a Population, Intervention, Comparator, and Outcomes format. A comprehensive literature search and evidence synthesis was performed for each question, which included appraising the certainty in the evidence (i.e., the quality of evidence) using the Grading of Recommendations, Assessment, Development, and Evaluation approach. The Evidence-to-Decision framework was applied to each question, requiring the panel to evaluate and weigh the importance of the problem, the confidence in the evidence, the certainty about how much the public values the main outcomes, the magnitude and balance of desirable and undesirable outcomes, the resources and costs associated with the intervention, the impact on health disparities, and the acceptability and feasibility of the intervention. RESULTS: Evidence-based recommendations were formulated and graded initially by subcommittees and then modified after full-panel discussions. The recommendations were confirmed by confidential electronic voting; approval required that at least 80% of the panel members agree with the recommendation. CONCLUSIONS: The panel provides recommendations regarding liberation from mechanical ventilation. The details regarding the evidence and rationale for each recommendation are presented in the American Journal of Respiratory and Critical Care Medicine and Chest. SN - 1535-4970 UR - https://www.unboundmedicine.com/medline/citation/27762608/full_citation L2 - http://www.atsjournals.org/doi/full/10.1164/rccm.201610-2076ST?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -