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Influence of Adaptive Statistical Iterative Reconstruction on coronary plaque analysis in coronary computed tomography angiography.
J Cardiovasc Comput Tomogr. 2016 Nov - Dec; 10(6):507-516.JC

Abstract

PURPOSE

The purpose of this study was to study the effect of iterative reconstruction (IR) software on quantitative plaque measurements in coronary computed tomography angiography (CCTA).

METHODS

Thirty patients with a three clinical risk factors for coronary artery disease (CAD) had one CCTA performed. Images were reconstructed using FBP, 30% and 60% adaptive statistical IR (ASIR). Coronary plaque analysis was performed as per patient and per vessel (LM, LAD, CX and RCA) measurements. Lumen and vessel volumes and plaque burden measurements were based on automatic detected contours in each reconstruction. Lumen and plaque intensity measurements and HU based plaque characterization were based on corrected contours copied to each reconstruction.

RESULTS

No significant changes between FBP and 30% ASIR were found except for lumen- (-2.53 HU) and plaque intensities (-1.28 HU). Between FBP and 60% ASIR the change in total volume showed an increase of 0.94%, 4.36% and 2.01% for lumen, plaque and vessel, respectively. The change in total plaque burden between FBP and 60% ASIR was 0.76%. Lumen and plaque intensities decreased between FBP and 60% ASIR with -9.90 HU and -1.97 HU, respectively. The total plaque component volume changes were all small with a maximum change of -1.13% of necrotic core between FBP and 60% ASIR.

CONCLUSIONS

Quantitative plaque measurements only showed modest differences between FBP and the 60% ASIR level. Differences were increased lumen-, vessel- and plaque volumes, decreased lumen- and plaque intensities and a small percentage change in the individual plaque component volumes.

Authors+Show Affiliations

Department of Medical Research, Odense University Hospital Svendborg, Valdemarsgade 53, Svendborg, Denmark; Conrad Research Center, University College Lillebaelt, Blangstedgaardsvej 4, 5220 Odense SØ, Denmark. Electronic address: hepr@ucl.dk.Department of Radiology, Division of Image Processing, Leiden University Medical Center, Albinusdreef 2, 2300 RC Leiden, The Netherlands; Medis medical imaging systems bv, Schuttersveld 9, 2300 AJ Leiden, The Netherlands.Department of Radiology, Division of Image Processing, Leiden University Medical Center, Albinusdreef 2, 2300 RC Leiden, The Netherlands.Department of Radiology, Division of Image Processing, Leiden University Medical Center, Albinusdreef 2, 2300 RC Leiden, The Netherlands.Department of Nuclear Medicine, Odense University Hospital, Sdr. Boulevard 29, Odense C, Denmark; Center of Health Economics Research, University of Southern Denmark, Campusvej 55, Odense M, Denmark.Department of Clinical Engineering, Central Denmark Region, Olof Palmes Allé 15, Århus N, Denmark.Department of Medical Research, Odense University Hospital Svendborg, Valdemarsgade 53, Svendborg, Denmark.Department of Medical Research, Odense University Hospital Svendborg, Valdemarsgade 53, Svendborg, Denmark.

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

27769663

Citation

Precht, Helle, et al. "Influence of Adaptive Statistical Iterative Reconstruction On Coronary Plaque Analysis in Coronary Computed Tomography Angiography." Journal of Cardiovascular Computed Tomography, vol. 10, no. 6, 2016, pp. 507-516.
Precht H, Kitslaar PH, Broersen A, et al. Influence of Adaptive Statistical Iterative Reconstruction on coronary plaque analysis in coronary computed tomography angiography. J Cardiovasc Comput Tomogr. 2016;10(6):507-516.
Precht, H., Kitslaar, P. H., Broersen, A., Dijkstra, J., Gerke, O., Thygesen, J., Egstrup, K., & Lambrechtsen, J. (2016). Influence of Adaptive Statistical Iterative Reconstruction on coronary plaque analysis in coronary computed tomography angiography. Journal of Cardiovascular Computed Tomography, 10(6), 507-516. https://doi.org/10.1016/j.jcct.2016.09.006
Precht H, et al. Influence of Adaptive Statistical Iterative Reconstruction On Coronary Plaque Analysis in Coronary Computed Tomography Angiography. J Cardiovasc Comput Tomogr. 2016 Nov - Dec;10(6):507-516. PubMed PMID: 27769663.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Influence of Adaptive Statistical Iterative Reconstruction on coronary plaque analysis in coronary computed tomography angiography. AU - Precht,Helle, AU - Kitslaar,Pieter H, AU - Broersen,Alexander, AU - Dijkstra,Jouke, AU - Gerke,Oke, AU - Thygesen,Jesper, AU - Egstrup,Kenneth, AU - Lambrechtsen,Jess, Y1 - 2016/09/28/ PY - 2014/10/03/received PY - 2016/09/22/revised PY - 2016/09/26/accepted PY - 2016/10/23/pubmed PY - 2017/4/25/medline PY - 2016/10/23/entrez KW - ASIR KW - Coronary CTA KW - Iterative reconstructions KW - Plaque analysis KW - Radiation dose reduction SP - 507 EP - 516 JF - Journal of cardiovascular computed tomography JO - J Cardiovasc Comput Tomogr VL - 10 IS - 6 N2 - PURPOSE: The purpose of this study was to study the effect of iterative reconstruction (IR) software on quantitative plaque measurements in coronary computed tomography angiography (CCTA). METHODS: Thirty patients with a three clinical risk factors for coronary artery disease (CAD) had one CCTA performed. Images were reconstructed using FBP, 30% and 60% adaptive statistical IR (ASIR). Coronary plaque analysis was performed as per patient and per vessel (LM, LAD, CX and RCA) measurements. Lumen and vessel volumes and plaque burden measurements were based on automatic detected contours in each reconstruction. Lumen and plaque intensity measurements and HU based plaque characterization were based on corrected contours copied to each reconstruction. RESULTS: No significant changes between FBP and 30% ASIR were found except for lumen- (-2.53 HU) and plaque intensities (-1.28 HU). Between FBP and 60% ASIR the change in total volume showed an increase of 0.94%, 4.36% and 2.01% for lumen, plaque and vessel, respectively. The change in total plaque burden between FBP and 60% ASIR was 0.76%. Lumen and plaque intensities decreased between FBP and 60% ASIR with -9.90 HU and -1.97 HU, respectively. The total plaque component volume changes were all small with a maximum change of -1.13% of necrotic core between FBP and 60% ASIR. CONCLUSIONS: Quantitative plaque measurements only showed modest differences between FBP and the 60% ASIR level. Differences were increased lumen-, vessel- and plaque volumes, decreased lumen- and plaque intensities and a small percentage change in the individual plaque component volumes. SN - 1876-861X UR - https://www.unboundmedicine.com/medline/citation/27769663/Influence_of_Adaptive_Statistical_Iterative_Reconstruction_on_coronary_plaque_analysis_in_coronary_computed_tomography_angiography_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1934-5925(16)30237-4 DB - PRIME DP - Unbound Medicine ER -