Tags

Type your tag names separated by a space and hit enter

Benign Papillomas of the Breast Diagnosed on Large-Gauge Vacuum Biopsy compared with 14 Gauge Core Needle Biopsy - Do they require surgical excision?
Breast J. 2017 Mar; 23(2):146-153.BJ

Abstract

To evaluate whether biopsy with vacuum-assisted biopsy (VAB) devices improves histologic underestimation rates of benign papillomas when compared to smaller bore core needle biopsy (CNB) devices. Patients with biopsy-proven benign papillomas with surgical resection or minimum 12 months follow-up were selected. Two breast pathologists reviewed all pathology slides of percutaneous and excisional biopsy specimens. Histologic underestimation rates for lesions biopsied with 10-12 Gauge (G) VAB were compared to those with 14G CNB. A total of 107 benign papillomas in 107 patients from two centers were included. There were 60 patients (mean age 57 years, SD 10.3 years) diagnosed with VAB and 47 patients (mean age 57.6 years, SD 11.3 years) with 14G CNB who underwent surgical excision or imaging follow-up. The upgrade rate to ductal carcinoma in situ or invasive carcinoma was 1.6% (1/60) with VAB and 8.5% (4/47) with 14G. Upgrade to atypia was 3.3% (2/60) after VAB and 10.6% (5/47) with CNB. The total underestimation rates were 5% (3/60) with VAB and 19.1% (9/47) with CNB. The odds of an upgrade to malignancy was 5.5 times higher with a 14G needle than VAB (95% CI: 0.592-50.853, p = 0.17). We observed a lower but not statistically significant upgrade rate to malignancy and atypia with the use of the 10-12 G VAB as compared with 14G CNB. When a papilloma without atypia is diagnosed with vacuum biopsy there is a high likelihood that it is benign; however, if surgical excision is not performed, long-term follow-up is still required.

Authors+Show Affiliations

Department of Medical Imaging, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada.The Ottawa Hospital, Ottawa, Ontario, Canada. University of Ottawa, Ottawa, Ontario, Canada.The Ottawa Hospital, Ottawa, Ontario, Canada. University of Ottawa, Ottawa, Ontario, Canada. Royal Victoria Hospital, Barrie, Ontario, Canada.The Ottawa Hospital, Ottawa, Ontario, Canada. University of Ottawa, Ottawa, Ontario, Canada.Sunnybrook Hospital, Toronto, Ontario, Canada.Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada.Department of Pathology, The Ottawa Hospital, Ottawa, Ontario, Canada.Royal Victoria Hospital, Barrie, Ontario, Canada.

Pub Type(s)

Comparative Study
Journal Article
Multicenter Study

Language

eng

PubMed ID

27797135

Citation

Seely, Jean M., et al. "Benign Papillomas of the Breast Diagnosed On Large-Gauge Vacuum Biopsy Compared With 14 Gauge Core Needle Biopsy - Do They Require Surgical Excision?" The Breast Journal, vol. 23, no. 2, 2017, pp. 146-153.
Seely JM, Verma R, Kielar A, et al. Benign Papillomas of the Breast Diagnosed on Large-Gauge Vacuum Biopsy compared with 14 Gauge Core Needle Biopsy - Do they require surgical excision? Breast J. 2017;23(2):146-153.
Seely, J. M., Verma, R., Kielar, A., Smyth, K. R., Hack, K., Taljaard, M., Gravel, D., & Ellison, E. (2017). Benign Papillomas of the Breast Diagnosed on Large-Gauge Vacuum Biopsy compared with 14 Gauge Core Needle Biopsy - Do they require surgical excision? The Breast Journal, 23(2), 146-153. https://doi.org/10.1111/tbj.12702
Seely JM, et al. Benign Papillomas of the Breast Diagnosed On Large-Gauge Vacuum Biopsy Compared With 14 Gauge Core Needle Biopsy - Do They Require Surgical Excision. Breast J. 2017;23(2):146-153. PubMed PMID: 27797135.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Benign Papillomas of the Breast Diagnosed on Large-Gauge Vacuum Biopsy compared with 14 Gauge Core Needle Biopsy - Do they require surgical excision? AU - Seely,Jean M, AU - Verma,Raman, AU - Kielar,Ania, AU - Smyth,Karl R, AU - Hack,Kalesha, AU - Taljaard,Monica, AU - Gravel,Denis, AU - Ellison,Erin, Y1 - 2016/10/31/ PY - 2016/11/1/pubmed PY - 2017/5/16/medline PY - 2016/11/1/entrez KW - biopsy KW - breast diseases KW - breast mammography KW - breast neoplasms KW - breast ultrasonography KW - core biopsy KW - papillary lesions KW - papillomas KW - underestimation rate KW - vacuum-assisted biopsy SP - 146 EP - 153 JF - The breast journal JO - Breast J VL - 23 IS - 2 N2 - To evaluate whether biopsy with vacuum-assisted biopsy (VAB) devices improves histologic underestimation rates of benign papillomas when compared to smaller bore core needle biopsy (CNB) devices. Patients with biopsy-proven benign papillomas with surgical resection or minimum 12 months follow-up were selected. Two breast pathologists reviewed all pathology slides of percutaneous and excisional biopsy specimens. Histologic underestimation rates for lesions biopsied with 10-12 Gauge (G) VAB were compared to those with 14G CNB. A total of 107 benign papillomas in 107 patients from two centers were included. There were 60 patients (mean age 57 years, SD 10.3 years) diagnosed with VAB and 47 patients (mean age 57.6 years, SD 11.3 years) with 14G CNB who underwent surgical excision or imaging follow-up. The upgrade rate to ductal carcinoma in situ or invasive carcinoma was 1.6% (1/60) with VAB and 8.5% (4/47) with 14G. Upgrade to atypia was 3.3% (2/60) after VAB and 10.6% (5/47) with CNB. The total underestimation rates were 5% (3/60) with VAB and 19.1% (9/47) with CNB. The odds of an upgrade to malignancy was 5.5 times higher with a 14G needle than VAB (95% CI: 0.592-50.853, p = 0.17). We observed a lower but not statistically significant upgrade rate to malignancy and atypia with the use of the 10-12 G VAB as compared with 14G CNB. When a papilloma without atypia is diagnosed with vacuum biopsy there is a high likelihood that it is benign; however, if surgical excision is not performed, long-term follow-up is still required. SN - 1524-4741 UR - https://www.unboundmedicine.com/medline/citation/27797135/Benign_Papillomas_of_the_Breast_Diagnosed_on_Large_Gauge_Vacuum_Biopsy_compared_with_14_Gauge_Core_Needle_Biopsy___Do_they_require_surgical_excision L2 - https://doi.org/10.1111/tbj.12702 DB - PRIME DP - Unbound Medicine ER -