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[Thiamine (vitamin B1) treatment in patients with alcohol dependence].
Presse Med. 2017 Mar; 46(2 Pt 1):165-171.PM

Abstract

Thiamine deficiency (vitamin B1) is common in patients with alcohol dependence. Cognitive impairments may be an early consequence of thiamine deficiency. Wernicke's encephalopathy is underdiagnosed and undertreated. In patients with established Wernicke's encephalopathy, parenteral thiamine 200-500mg three times a day should be given for 3-5 days, followed by oral thiamine 250-1000mg/day. In patients with suspected Wernicke's encephalopathy, parenteral thiamine 250-300mg should be given two times a day for 3-5 days, followed by oral thiamine 250-300mg/day. In patients at high risk of thiamine deficiency, parenteral thiamine 250-500mg/day should be given for 3-5 days, followed by oral thiamine 250-300mg/day. In patients at low risk (with uncomplicated alcohol dependence), oral thiamine 250-500mg/day should be given for 3-5 days, followed by oral thiamine 100-250mg/day.

Authors+Show Affiliations

Centre hospitalier Sainte-Anne, université Paris 5, Descartes, service d'addictologie, 1, rue Cabanis, 75014 Paris, France. Electronic address: a.dervaux@ch-sainte-anne.fr.Centre hospitalier Sainte-Anne, université Paris 5, Descartes, service d'addictologie, 1, rue Cabanis, 75014 Paris, France.

Pub Type(s)

Journal Article
Review

Language

fre

PubMed ID

27818067

Citation

Dervaux, Alain, and Xavier Laqueille. "[Thiamine (vitamin B1) Treatment in Patients With Alcohol Dependence]." Presse Medicale (Paris, France : 1983), vol. 46, no. 2 Pt 1, 2017, pp. 165-171.
Dervaux A, Laqueille X. [Thiamine (vitamin B1) treatment in patients with alcohol dependence]. Presse Med. 2017;46(2 Pt 1):165-171.
Dervaux, A., & Laqueille, X. (2017). [Thiamine (vitamin B1) treatment in patients with alcohol dependence]. Presse Medicale (Paris, France : 1983), 46(2 Pt 1), 165-171. https://doi.org/10.1016/j.lpm.2016.07.025
Dervaux A, Laqueille X. [Thiamine (vitamin B1) Treatment in Patients With Alcohol Dependence]. Presse Med. 2017;46(2 Pt 1):165-171. PubMed PMID: 27818067.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Thiamine (vitamin B1) treatment in patients with alcohol dependence]. AU - Dervaux,Alain, AU - Laqueille,Xavier, Y1 - 2016/11/03/ PY - 2016/05/17/received PY - 2016/06/15/revised PY - 2016/07/11/accepted PY - 2016/11/8/pubmed PY - 2017/4/7/medline PY - 2016/11/8/entrez SP - 165 EP - 171 JF - Presse medicale (Paris, France : 1983) JO - Presse Med VL - 46 IS - 2 Pt 1 N2 - Thiamine deficiency (vitamin B1) is common in patients with alcohol dependence. Cognitive impairments may be an early consequence of thiamine deficiency. Wernicke's encephalopathy is underdiagnosed and undertreated. In patients with established Wernicke's encephalopathy, parenteral thiamine 200-500mg three times a day should be given for 3-5 days, followed by oral thiamine 250-1000mg/day. In patients with suspected Wernicke's encephalopathy, parenteral thiamine 250-300mg should be given two times a day for 3-5 days, followed by oral thiamine 250-300mg/day. In patients at high risk of thiamine deficiency, parenteral thiamine 250-500mg/day should be given for 3-5 days, followed by oral thiamine 250-300mg/day. In patients at low risk (with uncomplicated alcohol dependence), oral thiamine 250-500mg/day should be given for 3-5 days, followed by oral thiamine 100-250mg/day. SN - 2213-0276 UR - https://www.unboundmedicine.com/medline/citation/27818067/[Thiamine__vitamin_B1__treatment_in_patients_with_alcohol_dependence]_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0755-4982(16)30307-4 DB - PRIME DP - Unbound Medicine ER -