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Primary cicatricial alopecia: Lymphocytic primary cicatricial alopecias, including chronic cutaneous lupus erythematosus, lichen planopilaris, frontal fibrosing alopecia, and Graham-Little syndrome.
J Am Acad Dermatol. 2016 Dec; 75(6):1081-1099.JA

Abstract

Both primary and secondary forms of cicatricial alopecia have been described. The hair follicles are the specific target of inflammation in primary cicatricial alopecias. Hair follicles are destroyed randomly with surrounding structures in secondary cicatricial alopecia. This 2-part continuing medical education article will review primary cicatricial alopecias according to the working classification suggested by the North American Hair Research Society. In this classification, the different entities are classified into 3 different groups according to their prominent inflammatory infiltrate (ie, lymphocytic, neutrophilic, and mixed). Part I discusses the following lymphocytic primary cicatricial alopecias: chronic cutaneous lupus erythematosus, lichen planopilaris, frontal fibrosing alopecia, and Graham-Little syndrome.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Bolduc C
Department of Dermatology, University of Montreal, Montreal, Quebec, Canada. Electronic address: chantal.bolduc1@gmail.com.
Sperling LC
Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, Maryland; Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
Shapiro J
Department of Dermatology, University of British Columbia, Vancouver, British Columbia, Canada; Department of Dermatology, New York University, New York, New York.

MeSH

AlopeciaCicatrixHumansLichen PlanusLupus Erythematosus, Discoid

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

27846944

Citation

Bolduc, Chantal, et al. "Primary Cicatricial Alopecia: Lymphocytic Primary Cicatricial Alopecias, Including Chronic Cutaneous Lupus Erythematosus, Lichen Planopilaris, Frontal Fibrosing Alopecia, and Graham-Little Syndrome." Journal of the American Academy of Dermatology, vol. 75, no. 6, 2016, pp. 1081-1099.
Bolduc C, Sperling LC, Shapiro J. Primary cicatricial alopecia: Lymphocytic primary cicatricial alopecias, including chronic cutaneous lupus erythematosus, lichen planopilaris, frontal fibrosing alopecia, and Graham-Little syndrome. J Am Acad Dermatol. 2016;75(6):1081-1099.
Bolduc, C., Sperling, L. C., & Shapiro, J. (2016). Primary cicatricial alopecia: Lymphocytic primary cicatricial alopecias, including chronic cutaneous lupus erythematosus, lichen planopilaris, frontal fibrosing alopecia, and Graham-Little syndrome. Journal of the American Academy of Dermatology, 75(6), 1081-1099. https://doi.org/10.1016/j.jaad.2014.09.058
Bolduc C, Sperling LC, Shapiro J. Primary Cicatricial Alopecia: Lymphocytic Primary Cicatricial Alopecias, Including Chronic Cutaneous Lupus Erythematosus, Lichen Planopilaris, Frontal Fibrosing Alopecia, and Graham-Little Syndrome. J Am Acad Dermatol. 2016;75(6):1081-1099. PubMed PMID: 27846944.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Primary cicatricial alopecia: Lymphocytic primary cicatricial alopecias, including chronic cutaneous lupus erythematosus, lichen planopilaris, frontal fibrosing alopecia, and Graham-Little syndrome. AU - Bolduc,Chantal, AU - Sperling,Leonard C, AU - Shapiro,Jerry, PY - 2014/04/14/received PY - 2014/09/14/revised PY - 2014/09/15/accepted PY - 2016/11/17/entrez PY - 2016/11/17/pubmed PY - 2017/4/21/medline KW - alopecia KW - cicatricial KW - fibrosis KW - follicles KW - hair KW - hair loss KW - lymphocytes KW - neutrophils KW - permanent SP - 1081 EP - 1099 JF - Journal of the American Academy of Dermatology JO - J Am Acad Dermatol VL - 75 IS - 6 N2 - Both primary and secondary forms of cicatricial alopecia have been described. The hair follicles are the specific target of inflammation in primary cicatricial alopecias. Hair follicles are destroyed randomly with surrounding structures in secondary cicatricial alopecia. This 2-part continuing medical education article will review primary cicatricial alopecias according to the working classification suggested by the North American Hair Research Society. In this classification, the different entities are classified into 3 different groups according to their prominent inflammatory infiltrate (ie, lymphocytic, neutrophilic, and mixed). Part I discusses the following lymphocytic primary cicatricial alopecias: chronic cutaneous lupus erythematosus, lichen planopilaris, frontal fibrosing alopecia, and Graham-Little syndrome. SN - 1097-6787 UR - https://www.unboundmedicine.com/medline/citation/27846944/Primary_cicatricial_alopecia:_Lymphocytic_primary_cicatricial_alopecias_including_chronic_cutaneous_lupus_erythematosus_lichen_planopilaris_frontal_fibrosing_alopecia_and_Graham_Little_syndrome_ DB - PRIME DP - Unbound Medicine ER -