Tags

Type your tag names separated by a space and hit enter

A randomized pilot trial of a positive affect skill intervention (lessons in linking affect and coping) for women with metastatic breast cancer.
Psychooncology 2017; 26(12):2101-2108P

Abstract

BACKGROUND

We conducted a randomized pilot trial to examine the feasibility, acceptability, and preliminary efficacy of a 5 week positive affect skills intervention (LILAC: lessons in linking affect and coping) for women with metastatic breast cancer. Additionally, we examined whether online delivery of the intervention would offer comparable benefits as in-person delivery.

METHODS

Women with metastatic breast cancer (N = 39) were randomized to an in-person intervention, online intervention, or in-person attention-matched control. Psychological well-being (depression [Center for Epidemiologic Studies Depression Scale], positive and negative affect [Differential Emotions Scale], cancer-specific quality of life [Multidimensional Quality of Life Scale-Cancer Version]), and positive coping (mindfulness, positive-affect skill use, and self-compassion [Self-Compassion Scale: Short-Form]) were assessed at baseline, 1 week post-intervention, and 1 month post-intervention follow-up.

RESULTS

The LILAC intervention showed good feasibility, acceptability, and retention. Although the study was not adequately powered to detect between-group differences in change on preliminary efficacy outcomes, within-group comparisons revealed that LILAC participants (in-person and online combined) showed reductions in depression and negative affect by the 1 month follow-up (d = -0.81). Notably, LILAC participants fell below the clinical threshold for depression (Center for Epidemiologic Studies Depression Scale = 16) by the 1 month follow-up (t[17] = -2.22, P = .04, d = -0.52), whereas control participants did not differ from threshold (t[9] = 0.45, P = .66, d = 0.14).

CONCLUSIONS

The LILAC intervention, regardless of delivery method, shows feasibility, acceptability, and preliminary efficacy for promoting psychological well-being in women with metastatic breast cancer. This research provides support for a larger randomized trial to test more definitively the potential benefits of LILAC. A strength of the LILAC intervention includes its innovative focus on positive affect. The efficacy of the online delivery suggests the potential for widespread Internet dissemination.

Authors+Show Affiliations

Northwestern University Feinberg School of Medicine, Chicago, IL, USA.University of California San Francisco, San Francisco, CA, USA.Stanford Medicine, Stanford, CA, USA.University of California San Francisco, San Francisco, CA, USA.University of California San Francisco, San Francisco, CA, USA.Northwestern University Feinberg School of Medicine, Chicago, IL, USA.Wake Forest School of Medicine, Winston-Salem, NC, USA.University of California San Francisco, San Francisco, CA, USA.Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

27862646

Citation

Cheung, Elaine O., et al. "A Randomized Pilot Trial of a Positive Affect Skill Intervention (lessons in Linking Affect and Coping) for Women With Metastatic Breast Cancer." Psycho-oncology, vol. 26, no. 12, 2017, pp. 2101-2108.
Cheung EO, Cohn MA, Dunn LB, et al. A randomized pilot trial of a positive affect skill intervention (lessons in linking affect and coping) for women with metastatic breast cancer. Psychooncology. 2017;26(12):2101-2108.
Cheung, E. O., Cohn, M. A., Dunn, L. B., Melisko, M. E., Morgan, S., Penedo, F. J., ... Moskowitz, J. T. (2017). A randomized pilot trial of a positive affect skill intervention (lessons in linking affect and coping) for women with metastatic breast cancer. Psycho-oncology, 26(12), pp. 2101-2108. doi:10.1002/pon.4312.
Cheung EO, et al. A Randomized Pilot Trial of a Positive Affect Skill Intervention (lessons in Linking Affect and Coping) for Women With Metastatic Breast Cancer. Psychooncology. 2017;26(12):2101-2108. PubMed PMID: 27862646.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A randomized pilot trial of a positive affect skill intervention (lessons in linking affect and coping) for women with metastatic breast cancer. AU - Cheung,Elaine O, AU - Cohn,Michael A, AU - Dunn,Laura B, AU - Melisko,Michelle E, AU - Morgan,Stefana, AU - Penedo,Frank J, AU - Salsman,John M, AU - Shumay,Dianne M, AU - Moskowitz,Judith T, Y1 - 2016/12/27/ PY - 2016/07/07/received PY - 2016/10/16/revised PY - 2016/11/11/accepted PY - 2016/11/20/pubmed PY - 2018/4/17/medline PY - 2016/11/19/entrez KW - cancer KW - metastatic breast cancer KW - oncology KW - online KW - positive Affect KW - well-being SP - 2101 EP - 2108 JF - Psycho-oncology JO - Psychooncology VL - 26 IS - 12 N2 - BACKGROUND: We conducted a randomized pilot trial to examine the feasibility, acceptability, and preliminary efficacy of a 5 week positive affect skills intervention (LILAC: lessons in linking affect and coping) for women with metastatic breast cancer. Additionally, we examined whether online delivery of the intervention would offer comparable benefits as in-person delivery. METHODS: Women with metastatic breast cancer (N = 39) were randomized to an in-person intervention, online intervention, or in-person attention-matched control. Psychological well-being (depression [Center for Epidemiologic Studies Depression Scale], positive and negative affect [Differential Emotions Scale], cancer-specific quality of life [Multidimensional Quality of Life Scale-Cancer Version]), and positive coping (mindfulness, positive-affect skill use, and self-compassion [Self-Compassion Scale: Short-Form]) were assessed at baseline, 1 week post-intervention, and 1 month post-intervention follow-up. RESULTS: The LILAC intervention showed good feasibility, acceptability, and retention. Although the study was not adequately powered to detect between-group differences in change on preliminary efficacy outcomes, within-group comparisons revealed that LILAC participants (in-person and online combined) showed reductions in depression and negative affect by the 1 month follow-up (d = -0.81). Notably, LILAC participants fell below the clinical threshold for depression (Center for Epidemiologic Studies Depression Scale = 16) by the 1 month follow-up (t[17] = -2.22, P = .04, d = -0.52), whereas control participants did not differ from threshold (t[9] = 0.45, P = .66, d = 0.14). CONCLUSIONS: The LILAC intervention, regardless of delivery method, shows feasibility, acceptability, and preliminary efficacy for promoting psychological well-being in women with metastatic breast cancer. This research provides support for a larger randomized trial to test more definitively the potential benefits of LILAC. A strength of the LILAC intervention includes its innovative focus on positive affect. The efficacy of the online delivery suggests the potential for widespread Internet dissemination. SN - 1099-1611 UR - https://www.unboundmedicine.com/medline/citation/27862646/A_randomized_pilot_trial_of_a_positive_affect_skill_intervention__lessons_in_linking_affect_and_coping__for_women_with_metastatic_breast_cancer_ L2 - https://doi.org/10.1002/pon.4312 DB - PRIME DP - Unbound Medicine ER -