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Long-term outcomes of transobturator tension-free vaginal tapes as secondary continence procedures.
World J Urol. 2017 Jul; 35(7):1141-1148.WJ

Abstract

PURPOSE

To assess the long-term patient-reported outcomes following TO-TVT as a secondary continence procedure in women with recurrent stress urinary incontinence (R-SUI).

METHODS

A secondary analysis of the 9-year follow-up of the E-TOT study was performed: 341 women with predominant SUI symptoms were randomised to undergo either Inside-out or Outside-in TO-TVT between April 2005 and April 2007. Forty-six women had R-SUI following previously failed continence surgery at time of randomisation and are the basis of this analysis as a one single cohort. Primary outcome was the patient-reported success rate defined as very/much improved on Patient's Global Impression of Improvement (PGI-I). Secondary outcomes included late adverse events and impact on women's quality of life and sexual function. Statistical analysis was performed using SPSS version 23.

RESULTS

Sixty-three per cent completed the 9-year follow-up. The success based on the PGI-I was 62.1% with no significant difference between groups (OR 5.33; 95% CI 1.03, 27.76; p = 0.094). Clinically significant improvement in QoL was found in 84.2%. Adverse events included vaginal erosions (n = 3) and groin pain (n = 2). The small sample size is a limitation in this study; nevertheless, this is one of the largest cohorts reported for women with R-SUI and the first to report the long-term outcomes of TO-TVT as a secondary continence procedure.

CONCLUSIONS

TO-TVT operations are associated with good patient-reported success rates (62%) in women with previous failed continence surgery with up to 9-years follow-up. There is a non-significant trend towards better outcomes with the inside-out TO-TVT.

Authors+Show Affiliations

Division of Applied Health Sciences, University of Aberdeen, Second Floor, Aberdeen Maternity Hospital, Foresterhill, AB25 2ZD, Aberdeen, UK. m.abdelfattah@abdn.ac.uk.University of Aberdeen, Aberdeen, UK.Division of Applied Health Sciences, University of Aberdeen, Second Floor, Aberdeen Maternity Hospital, Foresterhill, AB25 2ZD, Aberdeen, UK.

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

27864620

Citation

Abdel-Fattah, Mohamed, et al. "Long-term Outcomes of Transobturator Tension-free Vaginal Tapes as Secondary Continence Procedures." World Journal of Urology, vol. 35, no. 7, 2017, pp. 1141-1148.
Abdel-Fattah M, Cao G, Mostafa A. Long-term outcomes of transobturator tension-free vaginal tapes as secondary continence procedures. World J Urol. 2017;35(7):1141-1148.
Abdel-Fattah, M., Cao, G., & Mostafa, A. (2017). Long-term outcomes of transobturator tension-free vaginal tapes as secondary continence procedures. World Journal of Urology, 35(7), 1141-1148. https://doi.org/10.1007/s00345-016-1969-1
Abdel-Fattah M, Cao G, Mostafa A. Long-term Outcomes of Transobturator Tension-free Vaginal Tapes as Secondary Continence Procedures. World J Urol. 2017;35(7):1141-1148. PubMed PMID: 27864620.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Long-term outcomes of transobturator tension-free vaginal tapes as secondary continence procedures. AU - Abdel-Fattah,Mohamed, AU - Cao,Gabriel, AU - Mostafa,Alyaa, Y1 - 2016/11/18/ PY - 2016/09/23/received PY - 2016/11/04/accepted PY - 2016/11/20/pubmed PY - 2018/10/3/medline PY - 2016/11/20/entrez KW - Mid-urethral slings KW - Stress urinary incontinence KW - Tension-free vaginal tape KW - Transobturator tapes KW - Urinary incontinence SP - 1141 EP - 1148 JF - World journal of urology JO - World J Urol VL - 35 IS - 7 N2 - PURPOSE: To assess the long-term patient-reported outcomes following TO-TVT as a secondary continence procedure in women with recurrent stress urinary incontinence (R-SUI). METHODS: A secondary analysis of the 9-year follow-up of the E-TOT study was performed: 341 women with predominant SUI symptoms were randomised to undergo either Inside-out or Outside-in TO-TVT between April 2005 and April 2007. Forty-six women had R-SUI following previously failed continence surgery at time of randomisation and are the basis of this analysis as a one single cohort. Primary outcome was the patient-reported success rate defined as very/much improved on Patient's Global Impression of Improvement (PGI-I). Secondary outcomes included late adverse events and impact on women's quality of life and sexual function. Statistical analysis was performed using SPSS version 23. RESULTS: Sixty-three per cent completed the 9-year follow-up. The success based on the PGI-I was 62.1% with no significant difference between groups (OR 5.33; 95% CI 1.03, 27.76; p = 0.094). Clinically significant improvement in QoL was found in 84.2%. Adverse events included vaginal erosions (n = 3) and groin pain (n = 2). The small sample size is a limitation in this study; nevertheless, this is one of the largest cohorts reported for women with R-SUI and the first to report the long-term outcomes of TO-TVT as a secondary continence procedure. CONCLUSIONS: TO-TVT operations are associated with good patient-reported success rates (62%) in women with previous failed continence surgery with up to 9-years follow-up. There is a non-significant trend towards better outcomes with the inside-out TO-TVT. SN - 1433-8726 UR - https://www.unboundmedicine.com/medline/citation/27864620/Long_term_outcomes_of_transobturator_tension_free_vaginal_tapes_as_secondary_continence_procedures_ L2 - https://dx.doi.org/10.1007/s00345-016-1969-1 DB - PRIME DP - Unbound Medicine ER -