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The effects of oral contraceptives and parity on ovarian cancer trends in women under 55 years of age.
Br J Obstet Gynaecol. 1989 Jul; 96(7):783-8.BJ

Abstract

Mortality from epithelial ovarian cancer is falling in women under 55 years of age in England and Wales. The decline does not appear to be a treatment effect nor to be attributable to changes in the rate of oophorectomy. Case-control studies have shown that high parity and oral contraceptive use are protective against the disease. We suggest that the decrease in mortality is compatible in timing and magnitude with exposure to oral contraceptives. No obvious effect on mortality attributable to parity was apparent in this analysis. Oral contraceptives may prove to be a widely acceptable means of preventing ovarian cancer, providing they do not increase breast cancer risk.

Authors+Show Affiliations

Department of Community Medicine and General Practice, University of Oxford, Radcliffe Infirmary.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

2788456

Citation

Villard-Mackintosh, L, et al. "The Effects of Oral Contraceptives and Parity On Ovarian Cancer Trends in Women Under 55 Years of Age." British Journal of Obstetrics and Gynaecology, vol. 96, no. 7, 1989, pp. 783-8.
Villard-Mackintosh L, Vessey MP, Jones L. The effects of oral contraceptives and parity on ovarian cancer trends in women under 55 years of age. Br J Obstet Gynaecol. 1989;96(7):783-8.
Villard-Mackintosh, L., Vessey, M. P., & Jones, L. (1989). The effects of oral contraceptives and parity on ovarian cancer trends in women under 55 years of age. British Journal of Obstetrics and Gynaecology, 96(7), 783-8.
Villard-Mackintosh L, Vessey MP, Jones L. The Effects of Oral Contraceptives and Parity On Ovarian Cancer Trends in Women Under 55 Years of Age. Br J Obstet Gynaecol. 1989;96(7):783-8. PubMed PMID: 2788456.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The effects of oral contraceptives and parity on ovarian cancer trends in women under 55 years of age. AU - Villard-Mackintosh,L, AU - Vessey,M P, AU - Jones,L, PY - 1989/7/1/pubmed PY - 1989/7/1/medline PY - 1989/7/1/entrez KW - Age Factors KW - Cancer KW - Contraception KW - Contraceptive Methods--indications KW - Demographic Factors KW - Developed Countries KW - Diseases KW - England KW - Europe KW - Family Planning KW - Fertility KW - Fertility Measurements KW - Mortality--changes KW - Neoplasms KW - Northern Europe KW - Oral Contraceptives--indications KW - Ovarian Cancer--prevention and control KW - Parity KW - Population KW - Population Characteristics KW - Population Dynamics KW - United Kingdom KW - Wales SP - 783 EP - 8 JF - British journal of obstetrics and gynaecology JO - Br J Obstet Gynaecol VL - 96 IS - 7 N2 - Mortality from epithelial ovarian cancer is falling in women under 55 years of age in England and Wales. The decline does not appear to be a treatment effect nor to be attributable to changes in the rate of oophorectomy. Case-control studies have shown that high parity and oral contraceptive use are protective against the disease. We suggest that the decrease in mortality is compatible in timing and magnitude with exposure to oral contraceptives. No obvious effect on mortality attributable to parity was apparent in this analysis. Oral contraceptives may prove to be a widely acceptable means of preventing ovarian cancer, providing they do not increase breast cancer risk. SN - 0306-5456 UR - https://www.unboundmedicine.com/medline/citation/2788456/The_effects_of_oral_contraceptives_and_parity_on_ovarian_cancer_trends_in_women_under_55_years_of_age_ L2 - http://www.diseaseinfosearch.org/result/5395 DB - PRIME DP - Unbound Medicine ER -