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Refractory Chronic Rhinosinusitis with Nasal Polyposis.
Otolaryngol Clin North Am 2017; 50(1):61-81OC

Abstract

Chronic rhinosinusitis with nasal polyposis (CRSwNP) represents a subset of chronic sinusitis with various causes. Some forms of the disease are driven by allergy, often in association with asthma. Refractory CRSwNP can be associated with cystic fibrosis and other clinical syndromes. More recent literature is presented regarding roles of innate immunity and superantigens. Effective treatment of CRSwNP requires careful endoscopic sinus surgery followed by an individualized treatment plan that often includes oral and topical steroids. Recidivism of polyps is common, and patients require long-term follow-up.

Authors+Show Affiliations

Department of Otolaryngology-Head & Neck Surgery, Vanderbilt University, 1215 21st Ave S, 7209 MCE-S, Nashville, TN 37232-8605, USA.Department of Otolaryngology-Head & Neck Surgery, Vanderbilt University, 1215 21st Ave S, 7209 MCE-S, Nashville, TN 37232-8605, USA. Electronic address: Rakesh.chandra@vanderbilt.edu.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

27888916

Citation

Hull, Benjamin P., and Rakesh K. Chandra. "Refractory Chronic Rhinosinusitis With Nasal Polyposis." Otolaryngologic Clinics of North America, vol. 50, no. 1, 2017, pp. 61-81.
Hull BP, Chandra RK. Refractory Chronic Rhinosinusitis with Nasal Polyposis. Otolaryngol Clin North Am. 2017;50(1):61-81.
Hull, B. P., & Chandra, R. K. (2017). Refractory Chronic Rhinosinusitis with Nasal Polyposis. Otolaryngologic Clinics of North America, 50(1), pp. 61-81. doi:10.1016/j.otc.2016.08.006.
Hull BP, Chandra RK. Refractory Chronic Rhinosinusitis With Nasal Polyposis. Otolaryngol Clin North Am. 2017;50(1):61-81. PubMed PMID: 27888916.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Refractory Chronic Rhinosinusitis with Nasal Polyposis. AU - Hull,Benjamin P, AU - Chandra,Rakesh K, PY - 2016/11/28/entrez PY - 2016/11/28/pubmed PY - 2017/3/28/medline KW - Allergic fungal sinusitis KW - Allergy KW - Asthma KW - Cystic fibrosis KW - Innate immunity KW - Polyps KW - Superantigen SP - 61 EP - 81 JF - Otolaryngologic clinics of North America JO - Otolaryngol. Clin. North Am. VL - 50 IS - 1 N2 - Chronic rhinosinusitis with nasal polyposis (CRSwNP) represents a subset of chronic sinusitis with various causes. Some forms of the disease are driven by allergy, often in association with asthma. Refractory CRSwNP can be associated with cystic fibrosis and other clinical syndromes. More recent literature is presented regarding roles of innate immunity and superantigens. Effective treatment of CRSwNP requires careful endoscopic sinus surgery followed by an individualized treatment plan that often includes oral and topical steroids. Recidivism of polyps is common, and patients require long-term follow-up. SN - 1557-8259 UR - https://www.unboundmedicine.com/medline/citation/27888916/Refractory_Chronic_Rhinosinusitis_with_Nasal_Polyposis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0030-6665(16)30164-5 DB - PRIME DP - Unbound Medicine ER -