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Schizophrenia in mid-adulthood after prenatal exposure to the Chinese Famine of 1959-1961.

Abstract

Analyzing data from a large-scale, nationally representative sample, this study examines the association between prenatal exposure to the Chinese Famine (1959-1961) and schizophrenia risk in mid-adulthood and its urban/rural-specific and gender-specific patterns. The results showed that the cohort conceived and born during the famine had a higher risk of schizophrenia in mid-adulthood than cohorts conceived and born before or after the famine. In addition, schizophrenia risk was higher for urban residents than for rural residents and higher for females than for males. Drawing on the psychiatric features of late-onset schizophrenia in mid-adulthood, we then offer some theoretical mechanisms to explain the cohort, urban/rural, and gender differences.

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  • Authors+Show Affiliations

    ,

    School of Social Development, Central University of Finance and Economics, No. 39, College South Road, Haidian District, Beijing 100081, China; Department of Sociology, University of Illinois at Urbana-Champaign, 3093 Lincoln Hall, 702 S. Wright Street, Urbana, IL 61801, USA. Electronic address: wctpku@gmail.com.

    School of Social Service Administration, University of Chicago, 969 E. 60th Street, Chicago, IL 60637, USA.

    Source

    Schizophrenia research 184: 2017 06 pg 21-25

    MeSH

    Aged
    China
    Cohort Studies
    Female
    Humans
    Male
    Middle Aged
    Pregnancy
    Prenatal Exposure Delayed Effects
    Rural Population
    Schizophrenia
    Sex Factors
    Starvation
    Urban Population

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    27894821

    Citation

    Wang, Cuntong, and Yudong Zhang. "Schizophrenia in Mid-adulthood After Prenatal Exposure to the Chinese Famine of 1959-1961." Schizophrenia Research, vol. 184, 2017, pp. 21-25.
    Wang C, Zhang Y. Schizophrenia in mid-adulthood after prenatal exposure to the Chinese Famine of 1959-1961. Schizophr Res. 2017;184:21-25.
    Wang, C., & Zhang, Y. (2017). Schizophrenia in mid-adulthood after prenatal exposure to the Chinese Famine of 1959-1961. Schizophrenia Research, 184, pp. 21-25. doi:10.1016/j.schres.2016.11.030.
    Wang C, Zhang Y. Schizophrenia in Mid-adulthood After Prenatal Exposure to the Chinese Famine of 1959-1961. Schizophr Res. 2017;184:21-25. PubMed PMID: 27894821.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Schizophrenia in mid-adulthood after prenatal exposure to the Chinese Famine of 1959-1961. AU - Wang,Cuntong, AU - Zhang,Yudong, Y1 - 2016/11/25/ PY - 2016/04/29/received PY - 2016/11/20/revised PY - 2016/11/21/accepted PY - 2016/11/30/pubmed PY - 2018/3/27/medline PY - 2016/11/30/entrez KW - Chinese famine KW - Mid-adulthood KW - Prenatal malnutrition KW - Schizophrenia risk SP - 21 EP - 25 JF - Schizophrenia research JO - Schizophr. Res. VL - 184 N2 - Analyzing data from a large-scale, nationally representative sample, this study examines the association between prenatal exposure to the Chinese Famine (1959-1961) and schizophrenia risk in mid-adulthood and its urban/rural-specific and gender-specific patterns. The results showed that the cohort conceived and born during the famine had a higher risk of schizophrenia in mid-adulthood than cohorts conceived and born before or after the famine. In addition, schizophrenia risk was higher for urban residents than for rural residents and higher for females than for males. Drawing on the psychiatric features of late-onset schizophrenia in mid-adulthood, we then offer some theoretical mechanisms to explain the cohort, urban/rural, and gender differences. SN - 1573-2509 UR - https://www.unboundmedicine.com/medline/citation/27894821/Schizophrenia_in_mid_adulthood_after_prenatal_exposure_to_the_Chinese_Famine_of_1959_1961_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0920-9964(16)30523-0 DB - PRIME DP - Unbound Medicine ER -