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Possible Drug-Herb Interaction between Herbal Supplement Containing Horsetail (Equisetum arvense) and Antiretroviral Drugs.
J Int Assoc Provid AIDS Care. 2017 Jan/Feb; 16(1):11-13.JI

Abstract

The use of alternative medicines, including herbs, is common among HIV-positive patients, even in those on antiretroviral treatment. Equisetum arvense, known as "horsetail," is mainly used for its diuretic properties. There are limited data about the pharmacological properties of this compound and the potential drug-herb interactions. The authors report 2 cases in which a possible drug-herb interaction may have led to virological breakthrough in patients who were maintained on the same regimen for many years, including lamivudine (3TC)/zidovudine (ZDV)/efavirenz (EFV) and emtricitabine (FTC)/tenofovir (TDF)/EFV, respectively. Therefore, a drug-herb interaction may be expected when these agents are taken concurrently. Until additional data are available, the authors advise clinicians to avoid this combination when possible.

Authors+Show Affiliations

1 Infectious Diseases Unit, Hospital Cosme Argerich, Buenos Aires, Argentina.1 Infectious Diseases Unit, Hospital Cosme Argerich, Buenos Aires, Argentina.1 Infectious Diseases Unit, Hospital Cosme Argerich, Buenos Aires, Argentina.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

27903949

Citation

Cordova, Ezequiel, et al. "Possible Drug-Herb Interaction Between Herbal Supplement Containing Horsetail (Equisetum Arvense) and Antiretroviral Drugs." Journal of the International Association of Providers of AIDS Care, vol. 16, no. 1, 2017, pp. 11-13.
Cordova E, Morganti L, Rodriguez C. Possible Drug-Herb Interaction between Herbal Supplement Containing Horsetail (Equisetum arvense) and Antiretroviral Drugs. J Int Assoc Provid AIDS Care. 2017;16(1):11-13.
Cordova, E., Morganti, L., & Rodriguez, C. (2017). Possible Drug-Herb Interaction between Herbal Supplement Containing Horsetail (Equisetum arvense) and Antiretroviral Drugs. Journal of the International Association of Providers of AIDS Care, 16(1), 11-13. https://doi.org/10.1177/2325957416680295
Cordova E, Morganti L, Rodriguez C. Possible Drug-Herb Interaction Between Herbal Supplement Containing Horsetail (Equisetum Arvense) and Antiretroviral Drugs. J Int Assoc Provid AIDS Care. 2017;16(1):11-13. PubMed PMID: 27903949.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Possible Drug-Herb Interaction between Herbal Supplement Containing Horsetail (Equisetum arvense) and Antiretroviral Drugs. AU - Cordova,Ezequiel, AU - Morganti,Laura, AU - Rodriguez,Claudia, Y1 - 2016/11/30/ PY - 2016/12/3/pubmed PY - 2017/12/9/medline PY - 2016/12/2/entrez KW - Equisetum arvense KW - HIV treatment KW - herb–drug interactions KW - horsetail SP - 11 EP - 13 JF - Journal of the International Association of Providers of AIDS Care JO - J Int Assoc Provid AIDS Care VL - 16 IS - 1 N2 - The use of alternative medicines, including herbs, is common among HIV-positive patients, even in those on antiretroviral treatment. Equisetum arvense, known as "horsetail," is mainly used for its diuretic properties. There are limited data about the pharmacological properties of this compound and the potential drug-herb interactions. The authors report 2 cases in which a possible drug-herb interaction may have led to virological breakthrough in patients who were maintained on the same regimen for many years, including lamivudine (3TC)/zidovudine (ZDV)/efavirenz (EFV) and emtricitabine (FTC)/tenofovir (TDF)/EFV, respectively. Therefore, a drug-herb interaction may be expected when these agents are taken concurrently. Until additional data are available, the authors advise clinicians to avoid this combination when possible. SN - 2325-9582 UR - https://www.unboundmedicine.com/medline/citation/27903949/Possible_Drug_Herb_Interaction_between_Herbal_Supplement_Containing_Horsetail__Equisetum_arvense__and_Antiretroviral_Drugs_ L2 - http://journals.sagepub.com/doi/full/10.1177/2325957416680295?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -