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Ecotoxicological effects and mechanism of CuO nanoparticles to individual organisms.
Environ Pollut. 2017 Feb; 221:209-217.EP

Abstract

Copper oxide nanoparticles (CuO NPs) are used extensively in a variety of applications such as antimicrobial agent, photo-catalyst and gas sensors. The expanding production and widespread utilization of CuO NPs may pose risks to individual organisms and ecosystem. Comprehensive understanding the CuO NPs-induced adverse effects and their underlying mechanism are of great importance to assess the environmental risk of CuO NPs and to expand their use safely. However, toxic effects of CuO NPs to individual organisms and the mechanism of their action are still deficient and ambiguities. To ensure the safely use of CuO NPs, more attention should be paid on the long-term and chronic effects of CuO NPs at low concentration. Efforts should be devoted to develop techniques to differentiate toxicities induced by CuO NPs or dissolved Cu2+, and to reduce the toxicity of CuO NPs by controlling the particle diameter, modifying surface characteristic, selecting proper exposure route and regulating the release of Cu2+ from CuO NPs. This review provides a brief overview of toxicity of CuO NPs to individual organisms with a broad range of taxa (microorganisms, algae, plants, invertebrates and vertebrates) and to discuss the underlying toxicity mechanisms including oxidative stress, dynamic unbalance and coordination effects.

Authors+Show Affiliations

School of Environment and Chemical Engineering, North China Electric Power University, Beijing 102206, PR China.School of Environment and Chemical Engineering, North China Electric Power University, Beijing 102206, PR China; Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, PR China.NAAM Research Group, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.School of Environment and Chemical Engineering, North China Electric Power University, Beijing 102206, PR China; Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, PR China; NAAM Research Group, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia. Electronic address: xkwang@ncepu.edu.cn.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

27939631

Citation

Hou, Jing, et al. "Ecotoxicological Effects and Mechanism of CuO Nanoparticles to Individual Organisms." Environmental Pollution (Barking, Essex : 1987), vol. 221, 2017, pp. 209-217.
Hou J, Wang X, Hayat T, et al. Ecotoxicological effects and mechanism of CuO nanoparticles to individual organisms. Environ Pollut. 2017;221:209-217.
Hou, J., Wang, X., Hayat, T., & Wang, X. (2017). Ecotoxicological effects and mechanism of CuO nanoparticles to individual organisms. Environmental Pollution (Barking, Essex : 1987), 221, 209-217. https://doi.org/10.1016/j.envpol.2016.11.066
Hou J, et al. Ecotoxicological Effects and Mechanism of CuO Nanoparticles to Individual Organisms. Environ Pollut. 2017;221:209-217. PubMed PMID: 27939631.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ecotoxicological effects and mechanism of CuO nanoparticles to individual organisms. AU - Hou,Jing, AU - Wang,Xiangxue, AU - Hayat,Tasawar, AU - Wang,Xiangke, Y1 - 2016/12/08/ PY - 2016/05/07/received PY - 2016/11/22/revised PY - 2016/11/24/accepted PY - 2016/12/13/pubmed PY - 2017/2/17/medline PY - 2016/12/13/entrez KW - CuO nanoparticles KW - Mechanism KW - Oxidative stress KW - Reactive oxygen species KW - Toxicity SP - 209 EP - 217 JF - Environmental pollution (Barking, Essex : 1987) JO - Environ Pollut VL - 221 N2 - Copper oxide nanoparticles (CuO NPs) are used extensively in a variety of applications such as antimicrobial agent, photo-catalyst and gas sensors. The expanding production and widespread utilization of CuO NPs may pose risks to individual organisms and ecosystem. Comprehensive understanding the CuO NPs-induced adverse effects and their underlying mechanism are of great importance to assess the environmental risk of CuO NPs and to expand their use safely. However, toxic effects of CuO NPs to individual organisms and the mechanism of their action are still deficient and ambiguities. To ensure the safely use of CuO NPs, more attention should be paid on the long-term and chronic effects of CuO NPs at low concentration. Efforts should be devoted to develop techniques to differentiate toxicities induced by CuO NPs or dissolved Cu2+, and to reduce the toxicity of CuO NPs by controlling the particle diameter, modifying surface characteristic, selecting proper exposure route and regulating the release of Cu2+ from CuO NPs. This review provides a brief overview of toxicity of CuO NPs to individual organisms with a broad range of taxa (microorganisms, algae, plants, invertebrates and vertebrates) and to discuss the underlying toxicity mechanisms including oxidative stress, dynamic unbalance and coordination effects. SN - 1873-6424 UR - https://www.unboundmedicine.com/medline/citation/27939631/Ecotoxicological_effects_and_mechanism_of_CuO_nanoparticles_to_individual_organisms_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0269-7491(16)32382-X DB - PRIME DP - Unbound Medicine ER -