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Population genetic data for ten miniSTR loci in the Sri Lankan population.
Int J Legal Med. 2017 Jul; 131(4):969-970.IJ

Abstract

Allele frequencies and forensically important parameters of ten autosomal miniSTR loci, D1S1677, D2S1776, D10S1248, D11S4463, D12SATA, D14S1434, D17S974, D18S853, D20S482, and D22S1045, were obtained for 278 unrelated adults from the Sri Lankan population. The combined power of discrimination and probability of exclusion was found to be 0.999999999621539 and 0.9979620, respectively. No significant deviations from Hardy-Weinberg equilibrium were observed except for D20S482 which conformed to HW expectations only after the application of a Bonferroni correction. The study suggests the potential use of these miniSTRs as a supplement or as a stand-alone STR marker system for the analysis of highly degraded evidence in Sri Lanka.

Authors+Show Affiliations

Genetech Molecular Diagnostics, 54, Kithulwatte Road, Colombo, 08, Sri Lanka. suraj@genetechsrilanka.com. Department of Zoology, University of Colombo, Colombo, 03, Sri Lanka. suraj@genetechsrilanka.com.Genetech Molecular Diagnostics, 54, Kithulwatte Road, Colombo, 08, Sri Lanka.Genetech Molecular Diagnostics, 54, Kithulwatte Road, Colombo, 08, Sri Lanka.Department of Zoology, University of Colombo, Colombo, 03, Sri Lanka.Genetech Molecular Diagnostics, 54, Kithulwatte Road, Colombo, 08, Sri Lanka.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

27957605

Citation

Goonawardhana, N D S., et al. "Population Genetic Data for Ten miniSTR Loci in the Sri Lankan Population." International Journal of Legal Medicine, vol. 131, no. 4, 2017, pp. 969-970.
Goonawardhana NDS, Jayasekara GSKW, Elanahai V, et al. Population genetic data for ten miniSTR loci in the Sri Lankan population. Int J Legal Med. 2017;131(4):969-970.
Goonawardhana, N. D. S., Jayasekara, G. S. K. W., Elanahai, V., Udagama, P. V., & Fernandopulle, N. D. (2017). Population genetic data for ten miniSTR loci in the Sri Lankan population. International Journal of Legal Medicine, 131(4), 969-970. https://doi.org/10.1007/s00414-016-1512-3
Goonawardhana NDS, et al. Population Genetic Data for Ten miniSTR Loci in the Sri Lankan Population. Int J Legal Med. 2017;131(4):969-970. PubMed PMID: 27957605.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Population genetic data for ten miniSTR loci in the Sri Lankan population. AU - Goonawardhana,N D S, AU - Jayasekara,G S K W, AU - Elanahai,V, AU - Udagama,P V, AU - Fernandopulle,N D, Y1 - 2016/12/12/ PY - 2016/09/13/received PY - 2016/12/02/accepted PY - 2016/12/14/pubmed PY - 2017/11/1/medline PY - 2016/12/14/entrez KW - Degraded DNA KW - Miniaturized short tandem repeats (miniSTR) KW - Sinhalese KW - Sri Lankan Moors KW - Sri Lankan Tamils SP - 969 EP - 970 JF - International journal of legal medicine JO - Int J Legal Med VL - 131 IS - 4 N2 - Allele frequencies and forensically important parameters of ten autosomal miniSTR loci, D1S1677, D2S1776, D10S1248, D11S4463, D12SATA, D14S1434, D17S974, D18S853, D20S482, and D22S1045, were obtained for 278 unrelated adults from the Sri Lankan population. The combined power of discrimination and probability of exclusion was found to be 0.999999999621539 and 0.9979620, respectively. No significant deviations from Hardy-Weinberg equilibrium were observed except for D20S482 which conformed to HW expectations only after the application of a Bonferroni correction. The study suggests the potential use of these miniSTRs as a supplement or as a stand-alone STR marker system for the analysis of highly degraded evidence in Sri Lanka. SN - 1437-1596 UR - https://www.unboundmedicine.com/medline/citation/27957605/Population_genetic_data_for_ten_miniSTR_loci_in_the_Sri_Lankan_population_ DB - PRIME DP - Unbound Medicine ER -