Citation
Giongo, Janice L., et al. "Trypanocidal Activity of the Compounds Present in Aniba Canelilla Oil Against Trypanosoma Evansi and Its Effects On Viability of Lymphocytes." Microbial Pathogenesis, vol. 103, 2017, pp. 13-18.
Giongo JL, Vaucher RA, Da Silva AS, et al. Trypanocidal activity of the compounds present in Aniba canelilla oil against Trypanosoma evansi and its effects on viability of lymphocytes. Microb Pathog. 2017;103:13-18.
Giongo, J. L., Vaucher, R. A., Da Silva, A. S., Oliveira, C. B., de Mattos, C. B., Baldissera, M. D., Sagrillo, M. R., Monteiro, S. G., Custódio, D. L., Souza de Matos, M., Sampaio, P. T., Teixeira, H. F., Koester, L. S., & da Veiga Junior, V. F. (2017). Trypanocidal activity of the compounds present in Aniba canelilla oil against Trypanosoma evansi and its effects on viability of lymphocytes. Microbial Pathogenesis, 103, 13-18. https://doi.org/10.1016/j.micpath.2016.12.006
Giongo JL, et al. Trypanocidal Activity of the Compounds Present in Aniba Canelilla Oil Against Trypanosoma Evansi and Its Effects On Viability of Lymphocytes. Microb Pathog. 2017;103:13-18. PubMed PMID: 27988226.
TY - JOUR
T1 - Trypanocidal activity of the compounds present in Aniba canelilla oil against Trypanosoma evansi and its effects on viability of lymphocytes.
AU - Giongo,Janice L,
AU - Vaucher,Rodrigo A,
AU - Da Silva,Aleksandro S,
AU - Oliveira,Camila B,
AU - de Mattos,Cristiane B,
AU - Baldissera,Matheus D,
AU - Sagrillo,Michele R,
AU - Monteiro,Silvia G,
AU - Custódio,Dayana L,
AU - Souza de Matos,Marcielly,
AU - Sampaio,Paulo T,
AU - Teixeira,Helder F,
AU - Koester,Letícia S,
AU - da Veiga Junior,Valdir F,
Y1 - 2016/12/14/
PY - 2016/08/30/received
PY - 2016/11/04/revised
PY - 2016/12/10/accepted
PY - 2016/12/19/pubmed
PY - 2017/4/7/medline
PY - 2016/12/19/entrez
KW - 1-Nitro-2-phenylethane
KW - Aniba canelilla
KW - Antiprotozoal activity
KW - Essential oil composition
KW - Methyleugenol
SP - 13
EP - 18
JF - Microbial pathogenesis
JO - Microb Pathog
VL - 103
N2 - Aniba canelilla (H.B.K.) Mez, popularly known as "casca-preciosa" (precious bark), is a plant of the Lauraceae family, widely distributed in the Amazon region. Its major constituent is 1-nitro-2-phenylethane, a rare molecule in plants which is responsible for this plant's cinnamon scent. The present study aimed to report the chemical characterization of the oil extracted from Aniba canelilla using gas-chromatography/mass spectrometry and to assess its in vitro trypanocidal activity against Trypanosoma evansi, a prevalent haemoflagellate parasite that affects a broad range of mammal species in Africa, Asia and South America. The oil presented 1-nitro-2-phenylethane (83.68%) and methyleugenol (14.83%) as the two major components. The essential oil as well as both major compounds were shown to exert trypanocidal effect. Methyleugenol was slightly more active than 1-nitro-2-phenylethane. In vitro studies showed that the oil extracted from the stems of A. canelilla may be regarded as a potential natural treatment for trypanosomosis, once proven their in vivo action, may be an interesting alternative in the treatment of infected animals with T. evansi.
SN - 1096-1208
UR - https://www.unboundmedicine.com/medline/citation/27988226/Trypanocidal_activity_of_the_compounds_present_in_Aniba_canelilla_oil_against_Trypanosoma_evansi_and_its_effects_on_viability_of_lymphocytes_
DB - PRIME
DP - Unbound Medicine
ER -
