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[Differential diagnosis of osteomalacia and other forms of renal osteodystrophy in terminal renal failure by dynamic scintigraphy with diphosphonate].
Ter Arkh. 1989; 61(6):105-9.TA

Abstract

During osteomalacia in patients with terminal renal failure, the coefficient of diphosphonate elimination from the blood bed (K1) was less than 0.1 min-1, which was determined by the rise of the concentration of uremic toxins, inhibiting interaction of the radiopharmaceutical with the bone, in the patients' tissues. Dynamic scintigraphy permits one to study the pharmacokinetics of diphosphonate in every patient and thus can be used for differential diagnosis between osteomalacia and other forms of renal osteodystrophy.

Authors

Novikov AI
No affiliation info available
Ermolenko AE
No affiliation info available
Ermakova IP
No affiliation info available
Baeva LB
No affiliation info available
Levitskiĭ ER
No affiliation info available

MeSH

Chronic Kidney Disease-Mineral and Bone DisorderDiagnosis, DifferentialHumansKidney Failure, ChronicOsteomalaciaRadionuclide ImagingTechnetium Tc 99m Medronate

Pub Type(s)

Journal Article

Language

rus

PubMed ID

2799693

Citation

Novikov, A I., et al. "[Differential Diagnosis of Osteomalacia and Other Forms of Renal Osteodystrophy in Terminal Renal Failure By Dynamic Scintigraphy With Diphosphonate]." Terapevticheskii Arkhiv, vol. 61, no. 6, 1989, pp. 105-9.
Novikov AI, Ermolenko AE, Ermakova IP, et al. [Differential diagnosis of osteomalacia and other forms of renal osteodystrophy in terminal renal failure by dynamic scintigraphy with diphosphonate]. Ter Arkh. 1989;61(6):105-9.
Novikov, A. I., Ermolenko, A. E., Ermakova, I. P., Baeva, L. B., & Levitskiĭ, E. R. (1989). [Differential diagnosis of osteomalacia and other forms of renal osteodystrophy in terminal renal failure by dynamic scintigraphy with diphosphonate]. Terapevticheskii Arkhiv, 61(6), 105-9.
Novikov AI, et al. [Differential Diagnosis of Osteomalacia and Other Forms of Renal Osteodystrophy in Terminal Renal Failure By Dynamic Scintigraphy With Diphosphonate]. Ter Arkh. 1989;61(6):105-9. PubMed PMID: 2799693.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Differential diagnosis of osteomalacia and other forms of renal osteodystrophy in terminal renal failure by dynamic scintigraphy with diphosphonate]. AU - Novikov,A I, AU - Ermolenko,A E, AU - Ermakova,I P, AU - Baeva,L B, AU - Levitskiĭ,E R, PY - 1989/1/1/pubmed PY - 1989/1/1/medline PY - 1989/1/1/entrez SP - 105 EP - 9 JF - Terapevticheskii arkhiv JO - Ter Arkh VL - 61 IS - 6 N2 - During osteomalacia in patients with terminal renal failure, the coefficient of diphosphonate elimination from the blood bed (K1) was less than 0.1 min-1, which was determined by the rise of the concentration of uremic toxins, inhibiting interaction of the radiopharmaceutical with the bone, in the patients' tissues. Dynamic scintigraphy permits one to study the pharmacokinetics of diphosphonate in every patient and thus can be used for differential diagnosis between osteomalacia and other forms of renal osteodystrophy. SN - 0040-3660 UR - https://www.unboundmedicine.com/medline/citation/2799693/[Differential_diagnosis_of_osteomalacia_and_other_forms_of_renal_osteodystrophy_in_terminal_renal_failure_by_dynamic_scintigraphy_with_diphosphonate]_ L2 - https://www.diseaseinfosearch.org/result/6208 DB - PRIME DP - Unbound Medicine ER -