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Long-term prognosis of patients with cirrhosis of the liver and upper gastrointestinal bleeding.
Am J Gastroenterol. 1989 Oct; 84(10):1239-43.AJ

Abstract

A study has been carried out on the 5-yr survival curves of 287 patients admitted with upper gastrointestinal bleeding and portal hypertension. In 78.7%, the cause of bleeding was from esophageal varices. Only 2.4% had noncirrhotic portal hypertension, and 80% were alcoholics. At 5 yr, the overall survival probability was 26.2%. The curve had three segments with survival rates of 69% at 2 wk and 46.6% at 12 months. According to Child's grade, the curves were very different at 2 wk, 12 months, and 60 months: Group A, 94.0, 78.0, and 51.8%; group B, 77.0, 46.0, and 32.2; group C, 52.0, 11.0, and 2.3%. The largest differences were observed in the first 2 wk immediately after the first bleeding. The recurrence of bleeding in a period of 6 months significantly decreased the survival. Age, as well as the introduction of prophylactic measures (propranolol or sclerotherapy), did not influence long-term survival. Alcohol abstinence was accompanied by better survival. This difference was due to the impact of abstinence only in group B patients.

Authors+Show Affiliations

Department of Medicine 2, University Hospital of Santa Maria, Lisbon, Portugal.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

2801674

Citation

Pinto, H C., et al. "Long-term Prognosis of Patients With Cirrhosis of the Liver and Upper Gastrointestinal Bleeding." The American Journal of Gastroenterology, vol. 84, no. 10, 1989, pp. 1239-43.
Pinto HC, Abrantes A, Esteves AV, et al. Long-term prognosis of patients with cirrhosis of the liver and upper gastrointestinal bleeding. Am J Gastroenterol. 1989;84(10):1239-43.
Pinto, H. C., Abrantes, A., Esteves, A. V., Almeida, H., & Correia, J. P. (1989). Long-term prognosis of patients with cirrhosis of the liver and upper gastrointestinal bleeding. The American Journal of Gastroenterology, 84(10), 1239-43.
Pinto HC, et al. Long-term Prognosis of Patients With Cirrhosis of the Liver and Upper Gastrointestinal Bleeding. Am J Gastroenterol. 1989;84(10):1239-43. PubMed PMID: 2801674.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Long-term prognosis of patients with cirrhosis of the liver and upper gastrointestinal bleeding. AU - Pinto,H C, AU - Abrantes,A, AU - Esteves,A V, AU - Almeida,H, AU - Correia,J P, PY - 1989/10/1/pubmed PY - 1989/10/1/medline PY - 1989/10/1/entrez SP - 1239 EP - 43 JF - The American journal of gastroenterology JO - Am J Gastroenterol VL - 84 IS - 10 N2 - A study has been carried out on the 5-yr survival curves of 287 patients admitted with upper gastrointestinal bleeding and portal hypertension. In 78.7%, the cause of bleeding was from esophageal varices. Only 2.4% had noncirrhotic portal hypertension, and 80% were alcoholics. At 5 yr, the overall survival probability was 26.2%. The curve had three segments with survival rates of 69% at 2 wk and 46.6% at 12 months. According to Child's grade, the curves were very different at 2 wk, 12 months, and 60 months: Group A, 94.0, 78.0, and 51.8%; group B, 77.0, 46.0, and 32.2; group C, 52.0, 11.0, and 2.3%. The largest differences were observed in the first 2 wk immediately after the first bleeding. The recurrence of bleeding in a period of 6 months significantly decreased the survival. Age, as well as the introduction of prophylactic measures (propranolol or sclerotherapy), did not influence long-term survival. Alcohol abstinence was accompanied by better survival. This difference was due to the impact of abstinence only in group B patients. SN - 0002-9270 UR - https://www.unboundmedicine.com/medline/citation/2801674/Long_term_prognosis_of_patients_with_cirrhosis_of_the_liver_and_upper_gastrointestinal_bleeding_ L2 - https://medlineplus.gov/cirrhosis.html DB - PRIME DP - Unbound Medicine ER -