Tags

Type your tag names separated by a space and hit enter

Combined spinal-epidural anesthesia with hypobaric ropivacaine in sitting position significantly increases the incidence of hypotension in parturients undergoing cesarean section.
J Obstet Gynaecol Res. 2017 Apr; 43(4):669-675.JO

Abstract

AIM

Maternal position during induction of combined spinal-epidural anesthesia (CSEA) may affect hemodynamics and block characteristics. This study aimed to assess whether the sitting position is more likely to induce hypotension and higher block level than the lateral position in CSEA with hypobaric ropivacaine.

METHODS

Ninety American Society of Anesthesiologists physical status I and II parturients undergoing elective cesarean section were randomized into three groups: the sitting, left-lateral, and right-lateral position groups. The L3-4 interspace was selected as the puncture site, and subarachnoid injection of 2.5 mL 0.5% hypobaric ropivacaine was administered. After the epidural catheter was inserted and fixed, the patient's position was changed to the left-leaning supine position. The blood pressure was measured once every 1 min followed by once every 3 min after the delivery. The sensory block level was regularly measured.

RESULTS

A total of 88 parturients were included in this study. The incidences of hypotension in the sitting, left-lateral, and right-lateral position groups were 72%, 38%, and 40%, respectively, P = 0.012. Incidence and total dose of the phenylephrine supplement in the sitting position group were significantly higher than in the other two groups. The sitting position group showed a significantly higher block level (T4 [T3, T4]) as compared to the left-lateral (T6 [T5, T6]) and right-lateral position groups (T6 [T4, T6]), P < 0.01. The Apgar scores of neonates at 1 min and 5 min, and the pH values of the umbilical arterial and venous blood were similar among the three groups.

CONCLUSION

As compared to the lateral positions, CSEA with hypobaric ropivacaine in the sitting position is more likely to cause hypotension and excessively high block level.

Authors+Show Affiliations

Department of Anesthesiology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.Department of Anesthesiology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.Department of Anesthesiology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.Department of Anesthesiology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.Department of Anesthesiology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.Department of Anesthesiology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

28026887

Citation

Xu, Zhendong, et al. "Combined Spinal-epidural Anesthesia With Hypobaric Ropivacaine in Sitting Position Significantly Increases the Incidence of Hypotension in Parturients Undergoing Cesarean Section." The Journal of Obstetrics and Gynaecology Research, vol. 43, no. 4, 2017, pp. 669-675.
Xu Z, Shen F, Zhang Y, et al. Combined spinal-epidural anesthesia with hypobaric ropivacaine in sitting position significantly increases the incidence of hypotension in parturients undergoing cesarean section. J Obstet Gynaecol Res. 2017;43(4):669-675.
Xu, Z., Shen, F., Zhang, Y., Tao, Y., Chen, X., & Liu, Z. (2017). Combined spinal-epidural anesthesia with hypobaric ropivacaine in sitting position significantly increases the incidence of hypotension in parturients undergoing cesarean section. The Journal of Obstetrics and Gynaecology Research, 43(4), 669-675. https://doi.org/10.1111/jog.13253
Xu Z, et al. Combined Spinal-epidural Anesthesia With Hypobaric Ropivacaine in Sitting Position Significantly Increases the Incidence of Hypotension in Parturients Undergoing Cesarean Section. J Obstet Gynaecol Res. 2017;43(4):669-675. PubMed PMID: 28026887.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Combined spinal-epidural anesthesia with hypobaric ropivacaine in sitting position significantly increases the incidence of hypotension in parturients undergoing cesarean section. AU - Xu,Zhendong, AU - Shen,Fuyi, AU - Zhang,Yueqi, AU - Tao,Yiyi, AU - Chen,Xiubing, AU - Liu,Zhiqiang, Y1 - 2016/12/27/ PY - 2016/6/19/received PY - 2016/10/9/revised PY - 2016/11/8/accepted PY - 2016/12/28/pubmed PY - 2017/8/8/medline PY - 2016/12/28/entrez KW - blood pressure KW - cesarean section KW - combined spinal-epidural anesthesia KW - maternal position SP - 669 EP - 675 JF - The journal of obstetrics and gynaecology research JO - J Obstet Gynaecol Res VL - 43 IS - 4 N2 - AIM: Maternal position during induction of combined spinal-epidural anesthesia (CSEA) may affect hemodynamics and block characteristics. This study aimed to assess whether the sitting position is more likely to induce hypotension and higher block level than the lateral position in CSEA with hypobaric ropivacaine. METHODS: Ninety American Society of Anesthesiologists physical status I and II parturients undergoing elective cesarean section were randomized into three groups: the sitting, left-lateral, and right-lateral position groups. The L3-4 interspace was selected as the puncture site, and subarachnoid injection of 2.5 mL 0.5% hypobaric ropivacaine was administered. After the epidural catheter was inserted and fixed, the patient's position was changed to the left-leaning supine position. The blood pressure was measured once every 1 min followed by once every 3 min after the delivery. The sensory block level was regularly measured. RESULTS: A total of 88 parturients were included in this study. The incidences of hypotension in the sitting, left-lateral, and right-lateral position groups were 72%, 38%, and 40%, respectively, P = 0.012. Incidence and total dose of the phenylephrine supplement in the sitting position group were significantly higher than in the other two groups. The sitting position group showed a significantly higher block level (T4 [T3, T4]) as compared to the left-lateral (T6 [T5, T6]) and right-lateral position groups (T6 [T4, T6]), P < 0.01. The Apgar scores of neonates at 1 min and 5 min, and the pH values of the umbilical arterial and venous blood were similar among the three groups. CONCLUSION: As compared to the lateral positions, CSEA with hypobaric ropivacaine in the sitting position is more likely to cause hypotension and excessively high block level. SN - 1447-0756 UR - https://www.unboundmedicine.com/medline/citation/28026887/Combined_spinal_epidural_anesthesia_with_hypobaric_ropivacaine_in_sitting_position_significantly_increases_the_incidence_of_hypotension_in_parturients_undergoing_cesarean_section_ DB - PRIME DP - Unbound Medicine ER -