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Major highlights of the CAR-TCR Summit, Boston, 2016.

Abstract

Cellular immunotherapies such as CAR-T cell therapy and TCR-T cell therapy are relatively new, highly promising approaches for the treatment of cancer. In CAR-T cell therapy, a patient's T cells are engineered to express chimeric antigen receptors targeting tumor-associated cell surface antigens. In TCR-T cell therapy, the patient's T cells are engineered to express receptors targeting intracellular antigens. This report will summarize presentations from the recent CAR-TCR summit in Boston on September 13-16, 2016. These presentations were given by leaders in the field and many were divided into three streams: Discovery and Genetic T Cell Engineering; Translation and Clinical Development; and Manufacturing, Supply Chain and Commercialization. The report summarizes major pharmaceutical companies developing these novel therapies and provides challenges and perspectives for future therapeutic developments.

Authors+Show Affiliations

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Promab Biotechnologies Richmond, CA,. United States.

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Promab Biotechnologies Richmond, CA,. United States.

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Promab Biotechnologies Richmond, CA,. United States.

Source

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28071584