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Celiac disease: a clinical review.
Abdom Radiol (NY) 2017; 42(2):351-360AR

Abstract

Celiac disease (CD) is an immune-mediated inflammatory enteropathy triggered by gluten exposure in genetically susceptible individuals. It has a high prevalence approaching 1% of the US population. A high index of suspicion is warranted to diagnose CD as frequently patients present with extraintestinal or atypical manifestations. CD is diagnosed by a combination of serum serologies and duodenal biopsies. The majority of patients will respond to a lifelong gluten-free diet which is the cornerstone of therapy. Complications such as refractory CD, ulcerative jejunoileitis, enteropathy associated T-cell lymphoma and small bowel adenocarcinoma occur in a minority of patients.

Authors+Show Affiliations

Division of Gastroenterology & Hepatology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA. albawardy.badr@mayo.edu.Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.Division of Gastroenterology & Hepatology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.Division of Gastroenterology & Hepatology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.Division of Gastroenterology & Hepatology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.Division of Gastroenterology & Hepatology, Mayo Clinic, 200 First Street, S.W., Rochester, MN, 55905, USA.

Pub Type(s)

Journal Article
Review
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

28078381

Citation

Al-Bawardy, Badr, et al. "Celiac Disease: a Clinical Review." Abdominal Radiology (New York), vol. 42, no. 2, 2017, pp. 351-360.
Al-Bawardy B, Codipilly DC, Rubio-Tapia A, et al. Celiac disease: a clinical review. Abdom Radiol (NY). 2017;42(2):351-360.
Al-Bawardy, B., Codipilly, D. C., Rubio-Tapia, A., Bruining, D. H., Hansel, S. L., & Murray, J. A. (2017). Celiac disease: a clinical review. Abdominal Radiology (New York), 42(2), pp. 351-360. doi:10.1007/s00261-016-1034-y.
Al-Bawardy B, et al. Celiac Disease: a Clinical Review. Abdom Radiol (NY). 2017;42(2):351-360. PubMed PMID: 28078381.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Celiac disease: a clinical review. AU - Al-Bawardy,Badr, AU - Codipilly,D Chamil, AU - Rubio-Tapia,Alberto, AU - Bruining,David H, AU - Hansel,Stephanie L, AU - Murray,Joseph A, PY - 2017/1/13/pubmed PY - 2018/3/20/medline PY - 2017/1/13/entrez KW - Celiac disease KW - Enteropathy KW - Gluten free KW - Refractory KW - Sprue KW - imaging SP - 351 EP - 360 JF - Abdominal radiology (New York) JO - Abdom Radiol (NY) VL - 42 IS - 2 N2 - Celiac disease (CD) is an immune-mediated inflammatory enteropathy triggered by gluten exposure in genetically susceptible individuals. It has a high prevalence approaching 1% of the US population. A high index of suspicion is warranted to diagnose CD as frequently patients present with extraintestinal or atypical manifestations. CD is diagnosed by a combination of serum serologies and duodenal biopsies. The majority of patients will respond to a lifelong gluten-free diet which is the cornerstone of therapy. Complications such as refractory CD, ulcerative jejunoileitis, enteropathy associated T-cell lymphoma and small bowel adenocarcinoma occur in a minority of patients. SN - 2366-0058 UR - https://www.unboundmedicine.com/medline/citation/28078381/Celiac_disease:_a_clinical_review_ L2 - https://dx.doi.org/10.1007/s00261-016-1034-y DB - PRIME DP - Unbound Medicine ER -