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Genetic polymorphism investigation of the Chinese Yi minority using PowerPlex® Y23 STR amplification system.
Int J Legal Med. 2017 May; 131(3):663-666.IJ

Abstract

Twenty-three Y-STR loci (DYS576, DYS389I, DYS389 II, DYS448, DYS19, DYS391, DYS481, DYS549, DYS533, DYS438, DYS437, DYS570, DYS635, DYS390, DYS439, DYS392, DYS393, DYS458 DYS456, DYS643, Y-GATA-H4, and DYS385a/b) included in the next-generation PowerPlex® Y23 System were first investigated in 311 unrelated, healthy male individuals from the Yi minority population residing in the Liangshan Yi Autonomous Prefecture, Sichuan, China. A total of 179 alleles and 297 haplotypes were discovered in the Yi group. In total, 285 haplotypes among them were unique, and the remaining 12 haplotypes were observed in two or three individuals. Haplotype discrimination capacity and haplotype diversity were 0.9550 and 0.9989, respectively. Genetic diversity ranged from 0.4550 (DYS437) to 0.9556 (DYS385a/b). Population comparisons between the Yi minority group and 10 Asian meta-populations comprising 58 individual populations were performed. Both multidimensional scaling plots and phylogenetic analyses demonstrated that the genetic structure of the Chinese Yi ethnicity was extremely different compared to Taiwan indigenous inhabitants among 10 Asian meta-populations. Additionally, the genetic structure resemblance of the Yi group was obtained from a geographically close population (Xuanwei Han) or similar language family groups (Thai populations). Besides, our study has demonstrated that the PowerPlex® Y23 System has high polymorphism in a Chinese Yi ethnic population and high discriminatory power for forensic purposes. Population data of the 23 Y-STR obtained from a Yi ethnic population has enriched the Chinese ethnic genetic information.

Authors+Show Affiliations

Department of Forensic Genetics, West China School of Basic Science and Forensic Medicine, Sichuan University (West China University of Medical Sciences), Chengdu, Sichuan, 610041, China.Center of Forensic Expertise, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, 563099, China. Department of Forensic Medicine, Zunyi Medical University, Zunyi, Guizhou, 563099, China.Department of Forensic Medicine, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, China.Department of Clinical Laboratory, the First People's Hospital of Liangshan Yi Autonomous Prefecture, Xichang, Sichuan, 615000, China.Department of Forensic Genetics, West China School of Basic Science and Forensic Medicine, Sichuan University (West China University of Medical Sciences), Chengdu, Sichuan, 610041, China.Department of Forensic Genetics, West China School of Basic Science and Forensic Medicine, Sichuan University (West China University of Medical Sciences), Chengdu, Sichuan, 610041, China. JingYanscu@163.com.Department of Forensic Genetics, West China School of Basic Science and Forensic Medicine, Sichuan University (West China University of Medical Sciences), Chengdu, Sichuan, 610041, China. forensic@scu.edu.cn.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28091725

Citation

He, GuangLin, et al. "Genetic Polymorphism Investigation of the Chinese Yi Minority Using PowerPlex® Y23 STR Amplification System." International Journal of Legal Medicine, vol. 131, no. 3, 2017, pp. 663-666.
He G, Chen P, Zou X, et al. Genetic polymorphism investigation of the Chinese Yi minority using PowerPlex® Y23 STR amplification system. Int J Legal Med. 2017;131(3):663-666.
He, G., Chen, P., Zou, X., Chen, X., Song, F., Yan, J., & Hou, Y. (2017). Genetic polymorphism investigation of the Chinese Yi minority using PowerPlex® Y23 STR amplification system. International Journal of Legal Medicine, 131(3), 663-666. https://doi.org/10.1007/s00414-017-1537-2
He G, et al. Genetic Polymorphism Investigation of the Chinese Yi Minority Using PowerPlex® Y23 STR Amplification System. Int J Legal Med. 2017;131(3):663-666. PubMed PMID: 28091725.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Genetic polymorphism investigation of the Chinese Yi minority using PowerPlex® Y23 STR amplification system. AU - He,GuangLin, AU - Chen,PengYu, AU - Zou,Xing, AU - Chen,Xu, AU - Song,Feng, AU - Yan,Jing, AU - Hou,YiPing, Y1 - 2017/01/16/ PY - 2016/11/19/received PY - 2017/01/10/accepted PY - 2017/1/17/pubmed PY - 2017/11/1/medline PY - 2017/1/17/entrez KW - Forensic genetics KW - Phylogenetic analysis KW - PowerPlex® Y23 system KW - Y-STR KW - Yi ethnicity SP - 663 EP - 666 JF - International journal of legal medicine JO - Int J Legal Med VL - 131 IS - 3 N2 - Twenty-three Y-STR loci (DYS576, DYS389I, DYS389 II, DYS448, DYS19, DYS391, DYS481, DYS549, DYS533, DYS438, DYS437, DYS570, DYS635, DYS390, DYS439, DYS392, DYS393, DYS458 DYS456, DYS643, Y-GATA-H4, and DYS385a/b) included in the next-generation PowerPlex® Y23 System were first investigated in 311 unrelated, healthy male individuals from the Yi minority population residing in the Liangshan Yi Autonomous Prefecture, Sichuan, China. A total of 179 alleles and 297 haplotypes were discovered in the Yi group. In total, 285 haplotypes among them were unique, and the remaining 12 haplotypes were observed in two or three individuals. Haplotype discrimination capacity and haplotype diversity were 0.9550 and 0.9989, respectively. Genetic diversity ranged from 0.4550 (DYS437) to 0.9556 (DYS385a/b). Population comparisons between the Yi minority group and 10 Asian meta-populations comprising 58 individual populations were performed. Both multidimensional scaling plots and phylogenetic analyses demonstrated that the genetic structure of the Chinese Yi ethnicity was extremely different compared to Taiwan indigenous inhabitants among 10 Asian meta-populations. Additionally, the genetic structure resemblance of the Yi group was obtained from a geographically close population (Xuanwei Han) or similar language family groups (Thai populations). Besides, our study has demonstrated that the PowerPlex® Y23 System has high polymorphism in a Chinese Yi ethnic population and high discriminatory power for forensic purposes. Population data of the 23 Y-STR obtained from a Yi ethnic population has enriched the Chinese ethnic genetic information. SN - 1437-1596 UR - https://www.unboundmedicine.com/medline/citation/28091725/Genetic_polymorphism_investigation_of_the_Chinese_Yi_minority_using_PowerPlex®_Y23_STR_amplification_system_ DB - PRIME DP - Unbound Medicine ER -