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Chemical Composition and Biological Activities of the Essential Oil from Leaves and Flowers of Pulicaria incisa sub. candolleana (Family Asteraceae).
Chem Biodivers 2017; 14(4)CB

Abstract

The composition of the essential oil isolated from leaves and flowers of Pulicaria incisa sub. candolleana E. Gamal-Eldin, growing in Egypt, was analysed by GC and GC-MS. Forty-nine and 68 compounds were identified from the oils of the leaves and flowers accounting for 86.69 and 84.29%, respectively of the total detected constituents. Both leaves and flowers oils were characterized by the high content of carvotanacetone with 66.01, 50.87 and chrysanthenone 13.26, 24.3%, respectively. The cytotoxic activity of both essential oils was evaluated against hepatocellular carcinoma cell line HEPG-2, using MTT assay and vinblastine as a reference drug. Leaf oil showed higher activity with IC50 11.4 μg/ml compared with 37.4 μg/ml for flower oil. The antimicrobial activity of both oils was evaluated using agar well diffusion method towards two representatives for each of Gram positive and Gram negative bacteria as well as four representatives for fungi. The minimum inhibitory concentration of both essential oils against bacterial and fungal strains was obtained in the range of 0.49 - 15.63 μg/ml.

Authors+Show Affiliations

Pharmacognosy Department, Faculty of Pharmacy, October University for Modern Sciences and Arts (MSA), Giza, Egypt.Pharmacognosy Department, Faculty of Pharmacy, October University for Modern Sciences and Arts (MSA), Giza, Egypt.Pharmacognosy Department, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.Pharmacognosy Department, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt. Pharmacology Department, Faculty of Medicine, Umm Al-Qura University, Makkah, 24382, Saudi Arabia.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28094467

Citation

Shahat, Esraa A., et al. "Chemical Composition and Biological Activities of the Essential Oil From Leaves and Flowers of Pulicaria Incisa Sub. Candolleana (Family Asteraceae)." Chemistry & Biodiversity, vol. 14, no. 4, 2017.
Shahat EA, Bakr RO, Eldahshan OA, et al. Chemical Composition and Biological Activities of the Essential Oil from Leaves and Flowers of Pulicaria incisa sub. candolleana (Family Asteraceae). Chem Biodivers. 2017;14(4).
Shahat, E. A., Bakr, R. O., Eldahshan, O. A., & Ayoub, N. A. (2017). Chemical Composition and Biological Activities of the Essential Oil from Leaves and Flowers of Pulicaria incisa sub. candolleana (Family Asteraceae). Chemistry & Biodiversity, 14(4), doi:10.1002/cbdv.201600156.
Shahat EA, et al. Chemical Composition and Biological Activities of the Essential Oil From Leaves and Flowers of Pulicaria Incisa Sub. Candolleana (Family Asteraceae). Chem Biodivers. 2017;14(4) PubMed PMID: 28094467.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chemical Composition and Biological Activities of the Essential Oil from Leaves and Flowers of Pulicaria incisa sub. candolleana (Family Asteraceae). AU - Shahat,Esraa A, AU - Bakr,Riham O, AU - Eldahshan,Omayma A, AU - Ayoub,Nahla A, PY - 2016/05/06/received PY - 2017/01/11/accepted PY - 2017/1/18/pubmed PY - 2017/4/25/medline PY - 2017/1/18/entrez KW - Antimicrobial activities KW - Cytotoxic activities KW - Essential oil KW - GC-MS Analysis KW - Pulicaria incisa sub. candolleana JF - Chemistry & biodiversity JO - Chem. Biodivers. VL - 14 IS - 4 N2 - The composition of the essential oil isolated from leaves and flowers of Pulicaria incisa sub. candolleana E. Gamal-Eldin, growing in Egypt, was analysed by GC and GC-MS. Forty-nine and 68 compounds were identified from the oils of the leaves and flowers accounting for 86.69 and 84.29%, respectively of the total detected constituents. Both leaves and flowers oils were characterized by the high content of carvotanacetone with 66.01, 50.87 and chrysanthenone 13.26, 24.3%, respectively. The cytotoxic activity of both essential oils was evaluated against hepatocellular carcinoma cell line HEPG-2, using MTT assay and vinblastine as a reference drug. Leaf oil showed higher activity with IC50 11.4 μg/ml compared with 37.4 μg/ml for flower oil. The antimicrobial activity of both oils was evaluated using agar well diffusion method towards two representatives for each of Gram positive and Gram negative bacteria as well as four representatives for fungi. The minimum inhibitory concentration of both essential oils against bacterial and fungal strains was obtained in the range of 0.49 - 15.63 μg/ml. SN - 1612-1880 UR - https://www.unboundmedicine.com/medline/citation/28094467/Chemical_Composition_and_Biological_Activities_of_the_Essential_Oil_from_Leaves_and_Flowers_of_Pulicaria_incisa_sub__candolleana__Family_Asteraceae__ L2 - https://doi.org/10.1002/cbdv.201600156 DB - PRIME DP - Unbound Medicine ER -