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Antioxidant and antimicrobial properties of bioactive phytochemicals from cranberry.

Abstract

In the rational human diet, the important role of fruits and vegetables, which are a source of bioactive phytochemicals, is emphasized. Among fruits particular attention, due to a number of documented health-promoting properties, is focused on cranberry. This fruit is characterized by the high content of antioxidant phenolic compounds, which may support the natural antioxidant defense system of the body in the prevention of damage caused by oxidative stress induced by reactive oxygen species (ROS). Therefore, cranberry is suggested for the prevention of civilization diseases such as atherosclerosis, hypertension and cancer, whose etiology is associated directly with oxidative stress. The health-promoting potential of cranberry is also associated with its antibacterial activity resulting from the presence of proanthocyanidins (PAC) type A with documented anti-adherence properties. The best-established medical applications of cranberry fruits are prevention and treatment of bacterial infections of the urinary tract (UTI), infections of gastric mucosa, and infections of the oral cavity. Due to the widespread use of cranberry and pharmaceutical preparations containing PACs in treating UTI, it is very important to evaluate the absorption, bioavailability and metabolism of these compounds in the human body.

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  • Authors+Show Affiliations

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    Katedra Chemii, Technologii i Biotechnologii Żywności, Wydział Chemiczny, Politechnika Gdańska.

    Katedra Chemii, Technologii i Biotechnologii Żywności, Wydział Chemiczny, Politechnika Gdańska.

    Source

    MeSH

    Anti-Infective Agents
    Antioxidants
    Fruit
    Humans
    Phenols
    Phytochemicals
    Proanthocyanidins
    Vaccinium macrocarpon

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    28100853

    Citation

    Baranowska, Monika, and Agnieszka Bartoszek. "Antioxidant and Antimicrobial Properties of Bioactive Phytochemicals From Cranberry." Postepy Higieny I Medycyny Doswiadczalnej (Online), vol. 70, no. 0, 2016, pp. 1460-1468.
    Baranowska M, Bartoszek A. Antioxidant and antimicrobial properties of bioactive phytochemicals from cranberry. Postepy Hig Med Dosw (Online). 2016;70(0):1460-1468.
    Baranowska, M., & Bartoszek, A. (2016). Antioxidant and antimicrobial properties of bioactive phytochemicals from cranberry. Postepy Higieny I Medycyny Doswiadczalnej (Online), 70(0), pp. 1460-1468. doi:10.5604/17322693.1227896.
    Baranowska M, Bartoszek A. Antioxidant and Antimicrobial Properties of Bioactive Phytochemicals From Cranberry. Postepy Hig Med Dosw (Online). 2016 Dec 31;70(0):1460-1468. PubMed PMID: 28100853.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Antioxidant and antimicrobial properties of bioactive phytochemicals from cranberry. AU - Baranowska,Monika, AU - Bartoszek,Agnieszka, Y1 - 2016/12/31/ PY - 2017/1/20/entrez PY - 2017/1/20/pubmed PY - 2017/7/29/medline SP - 1460 EP - 1468 JF - Postepy higieny i medycyny doswiadczalnej (Online) JO - Postepy Hig Med Dosw (Online) VL - 70 IS - 0 N2 - In the rational human diet, the important role of fruits and vegetables, which are a source of bioactive phytochemicals, is emphasized. Among fruits particular attention, due to a number of documented health-promoting properties, is focused on cranberry. This fruit is characterized by the high content of antioxidant phenolic compounds, which may support the natural antioxidant defense system of the body in the prevention of damage caused by oxidative stress induced by reactive oxygen species (ROS). Therefore, cranberry is suggested for the prevention of civilization diseases such as atherosclerosis, hypertension and cancer, whose etiology is associated directly with oxidative stress. The health-promoting potential of cranberry is also associated with its antibacterial activity resulting from the presence of proanthocyanidins (PAC) type A with documented anti-adherence properties. The best-established medical applications of cranberry fruits are prevention and treatment of bacterial infections of the urinary tract (UTI), infections of gastric mucosa, and infections of the oral cavity. Due to the widespread use of cranberry and pharmaceutical preparations containing PACs in treating UTI, it is very important to evaluate the absorption, bioavailability and metabolism of these compounds in the human body. SN - 1732-2693 UR - https://www.unboundmedicine.com/medline/citation/28100853/Antioxidant_and_antimicrobial_properties_of_bioactive_phytochemicals_from_cranberry_ L2 - http://www.phmd.pl/fulltxt.php?ICID=1227896 DB - PRIME DP - Unbound Medicine ER -