Tags

Type your tag names separated by a space and hit enter

A new diacetylated flavonol triglycoside from the aerial parts of Actinidia polygama.
Nat Prod Res. 2017 Jul; 31(13):1501-1508.NP

Abstract

Phytochemical investigation of a methanolic extract of aerial parts Actinidia polygama Miq. led to the isolation of one new diacetylated flavonol triglycoside, kaempferol 3-O-[α-L-rhamnopyranosyl(1→3)-(4-O-acetyl)-O-α-L-rhamnopyranosyl(1→6)-(2-Oacetyl)-O-β-D-galactopyranoside] (1) along with 12 known compounds (2-13). The chemical structures were determined using their spectroscopic data including 1D and 2D NMR. To the best of our knowledge, this is the first time that compounds 2, 4, 6, 7, 8, 9, 12 and 13 are isolated from this plant. All purified compounds were tested for free radical scavenging effect using DPPH and ABTS assays. Our results showed that compounds 4, 6, 7 and 13 have potential antioxidative effect for scavenging both DPPH· and ABTS·+ radicals that are comparable with those of ascorbic acid used as positive control, whereas compounds 1 and 2, which are di- and mono- acetylated flavonol triglycoside respectively, were not found to be potent scavengers of free radicals.

Authors+Show Affiliations

a College of Pharmacy and Institute of Pharmaceutical Science and Technology , Hanyang University , Ansan , Republic of Korea.a College of Pharmacy and Institute of Pharmaceutical Science and Technology , Hanyang University , Ansan , Republic of Korea.a College of Pharmacy and Institute of Pharmaceutical Science and Technology , Hanyang University , Ansan , Republic of Korea.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28114836

Citation

Syed, Ahmed Shah, et al. "A New Diacetylated Flavonol Triglycoside From the Aerial Parts of Actinidia Polygama." Natural Product Research, vol. 31, no. 13, 2017, pp. 1501-1508.
Syed AS, Jeon JS, Kim CY. A new diacetylated flavonol triglycoside from the aerial parts of Actinidia polygama. Nat Prod Res. 2017;31(13):1501-1508.
Syed, A. S., Jeon, J. S., & Kim, C. Y. (2017). A new diacetylated flavonol triglycoside from the aerial parts of Actinidia polygama. Natural Product Research, 31(13), 1501-1508. https://doi.org/10.1080/14786419.2017.1278592
Syed AS, Jeon JS, Kim CY. A New Diacetylated Flavonol Triglycoside From the Aerial Parts of Actinidia Polygama. Nat Prod Res. 2017;31(13):1501-1508. PubMed PMID: 28114836.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A new diacetylated flavonol triglycoside from the aerial parts of Actinidia polygama. AU - Syed,Ahmed Shah, AU - Jeon,Je-Seung, AU - Kim,Chul Young, Y1 - 2017/01/23/ PY - 2017/1/25/pubmed PY - 2017/9/25/medline PY - 2017/1/25/entrez KW - Actinidia polygama KW - flavonol glycosides, antioxidant activity KW - phenolic compounds SP - 1501 EP - 1508 JF - Natural product research JO - Nat Prod Res VL - 31 IS - 13 N2 - Phytochemical investigation of a methanolic extract of aerial parts Actinidia polygama Miq. led to the isolation of one new diacetylated flavonol triglycoside, kaempferol 3-O-[α-L-rhamnopyranosyl(1→3)-(4-O-acetyl)-O-α-L-rhamnopyranosyl(1→6)-(2-Oacetyl)-O-β-D-galactopyranoside] (1) along with 12 known compounds (2-13). The chemical structures were determined using their spectroscopic data including 1D and 2D NMR. To the best of our knowledge, this is the first time that compounds 2, 4, 6, 7, 8, 9, 12 and 13 are isolated from this plant. All purified compounds were tested for free radical scavenging effect using DPPH and ABTS assays. Our results showed that compounds 4, 6, 7 and 13 have potential antioxidative effect for scavenging both DPPH· and ABTS·+ radicals that are comparable with those of ascorbic acid used as positive control, whereas compounds 1 and 2, which are di- and mono- acetylated flavonol triglycoside respectively, were not found to be potent scavengers of free radicals. SN - 1478-6427 UR - https://www.unboundmedicine.com/medline/citation/28114836/A_new_diacetylated_flavonol_triglycoside_from_the_aerial_parts_of_Actinidia_polygama_ L2 - https://www.tandfonline.com/doi/full/10.1080/14786419.2017.1278592 DB - PRIME DP - Unbound Medicine ER -