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Reality of nerve sparing and surgical margins in surgeons' early experience with robot-assisted radical prostatectomy in Japan.
Int J Urol. 2017 03; 24(3):191-196.IJ

Abstract

OBJECTIVE

To analyze nerve sparing performance at an early stage of robot-assisted radical prostatectomy, and the correlation between the surgeons' experience and the risk of a positive surgical margin in patients treated with robot-assisted radical prostatectomy.

METHODS

Patients' records from January 2009 to March 2013 were retrospectively reviewed, and 3469 patients with localized prostate cancer were identified at 45 institutions. Individual surgeon's experience with nerve sparing was recorded as the number of nerve sparing cases among total robot-assisted radical prostatectomies beginning with the first case during which nerve sparing was carried out. Patients were selected by propensity score matching for nerve sparing, and predictive factors of positive surgical margins were analyzed in patients with and without positive surgical margins.

RESULTS

A total of 152 surgeons were studied, and the median number of robot-assisted radical prostatectomy cases for all surgeons was 21 (range 1-511). In all, 54 surgeons (35.5%) undertook nerve sparing during their first robot-assisted radical prostatectomy case. For 2388 patients selected with (1194) and without (1194) nerve sparing, predictive factors for positive surgical margin were high initial prostate-specific antigen level (P < 0.0001), high biopsy Gleason score (P = 0.0379), presence of neoadjuvant hormone therapy (P = 0.0002) and surgeon's experience with >100 cases (P = 0.0058). Thus, nerve sparing was not associated with positive surgical margins.

CONCLUSION

The surgeon's experience influences the occurrence of positive surgical margins, although a considerable number of surgeons carried out nerve sparing during their early robot-assisted radical prostatectomy cases. Surgeons should consider their own experience and prostate cancer characteristics before carrying out a nerve sparing robot-assisted radical prostatectomy.

Authors+Show Affiliations

Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.Department of Urology, Tokyo Medical University, Tokyo, Japan.Department of Urology, Fujita Health University School of Medicine, Aichi, Japan.Department of Urology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.Department of Urology, Nagoya University Graduate School of Medicine, Aichi, Japan.Department of Nephro-Urology, Nagoya City University Graduate School of Medical Sciences, Aichi, Japan.Department of Urology, Chiba Cancer Center, Chiba, Japan.Division of Urology, Department of Surgery Related, Kobe University Graduate School of Medicine, Hyogo, Japan.Division of Urology, Department of Surgery, Tottori University Faculty of Medicine, Tottori, Japan.Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.Department of Urology, Teine Keijinkai Medical Center, Hokkaido, Japan.Department of Urology, Nagoya University Graduate School of Medicine, Aichi, Japan.Department of Urology, Tokai University School of Medicine, Kanagawa, Japan.No affiliation info available

Pub Type(s)

Journal Article
Multicenter Study

Language

eng

PubMed ID

28122393

Citation

Tatsugami, Katsunori, et al. "Reality of Nerve Sparing and Surgical Margins in Surgeons' Early Experience With Robot-assisted Radical Prostatectomy in Japan." International Journal of Urology : Official Journal of the Japanese Urological Association, vol. 24, no. 3, 2017, pp. 191-196.
Tatsugami K, Yoshioka K, Shiroki R, et al. Reality of nerve sparing and surgical margins in surgeons' early experience with robot-assisted radical prostatectomy in Japan. Int J Urol. 2017;24(3):191-196.
Tatsugami, K., Yoshioka, K., Shiroki, R., Eto, M., Yoshino, Y., Tozawa, K., Fukasawa, S., Fujisawa, M., Takenaka, A., Nasu, Y., Kashiwagi, A., Gotoh, M., & Terachi, T. (2017). Reality of nerve sparing and surgical margins in surgeons' early experience with robot-assisted radical prostatectomy in Japan. International Journal of Urology : Official Journal of the Japanese Urological Association, 24(3), 191-196. https://doi.org/10.1111/iju.13281
Tatsugami K, et al. Reality of Nerve Sparing and Surgical Margins in Surgeons' Early Experience With Robot-assisted Radical Prostatectomy in Japan. Int J Urol. 2017;24(3):191-196. PubMed PMID: 28122393.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Reality of nerve sparing and surgical margins in surgeons' early experience with robot-assisted radical prostatectomy in Japan. AU - Tatsugami,Katsunori, AU - Yoshioka,Kunihiko, AU - Shiroki,Ryoichi, AU - Eto,Masatoshi, AU - Yoshino,Yasushi, AU - Tozawa,Keiichi, AU - Fukasawa,Satoshi, AU - Fujisawa,Masato, AU - Takenaka,Atsushi, AU - Nasu,Yasutomo, AU - Kashiwagi,Akira, AU - Gotoh,Momokazu, AU - Terachi,Toshiro, AU - ,, Y1 - 2017/01/25/ PY - 2016/06/08/received PY - 2016/11/24/accepted PY - 2017/1/26/pubmed PY - 2019/4/4/medline PY - 2017/1/26/entrez KW - nerve sparing KW - prostate cancer KW - prostatectomy KW - robotics KW - surgical margin SP - 191 EP - 196 JF - International journal of urology : official journal of the Japanese Urological Association JO - Int. J. Urol. VL - 24 IS - 3 N2 - OBJECTIVE: To analyze nerve sparing performance at an early stage of robot-assisted radical prostatectomy, and the correlation between the surgeons' experience and the risk of a positive surgical margin in patients treated with robot-assisted radical prostatectomy. METHODS: Patients' records from January 2009 to March 2013 were retrospectively reviewed, and 3469 patients with localized prostate cancer were identified at 45 institutions. Individual surgeon's experience with nerve sparing was recorded as the number of nerve sparing cases among total robot-assisted radical prostatectomies beginning with the first case during which nerve sparing was carried out. Patients were selected by propensity score matching for nerve sparing, and predictive factors of positive surgical margins were analyzed in patients with and without positive surgical margins. RESULTS: A total of 152 surgeons were studied, and the median number of robot-assisted radical prostatectomy cases for all surgeons was 21 (range 1-511). In all, 54 surgeons (35.5%) undertook nerve sparing during their first robot-assisted radical prostatectomy case. For 2388 patients selected with (1194) and without (1194) nerve sparing, predictive factors for positive surgical margin were high initial prostate-specific antigen level (P < 0.0001), high biopsy Gleason score (P = 0.0379), presence of neoadjuvant hormone therapy (P = 0.0002) and surgeon's experience with >100 cases (P = 0.0058). Thus, nerve sparing was not associated with positive surgical margins. CONCLUSION: The surgeon's experience influences the occurrence of positive surgical margins, although a considerable number of surgeons carried out nerve sparing during their early robot-assisted radical prostatectomy cases. Surgeons should consider their own experience and prostate cancer characteristics before carrying out a nerve sparing robot-assisted radical prostatectomy. SN - 1442-2042 UR - https://www.unboundmedicine.com/medline/citation/28122393/Reality_of_nerve_sparing_and_surgical_margins_in_surgeons'_early_experience_with_robot_assisted_radical_prostatectomy_in_Japan_ L2 - https://doi.org/10.1111/iju.13281 DB - PRIME DP - Unbound Medicine ER -