Tags

Type your tag names separated by a space and hit enter

Factors associated with influenza and pneumococcal vaccine uptake among rheumatoid arthritis patients in Denmark invited to participate in a pneumococcal vaccine trial (Immunovax_RA).
Scand J Rheumatol. 2017 Nov; 46(6):446-453.SJ

Abstract

OBJECTIVE

This study investigates predictors of influenza and pneumococcal vaccine coverage among rheumatoid arthritis (RA) patients, and explores possible differences according to type of RA therapy.

METHOD

RA patients from two clinics in the region of Southern Denmark were informed about the survey during scheduled follow-up visits. The questionnaire included questions concerning previous influenza and pneumococcal vaccine uptake, attitudes about vaccination, and socio-demographic factors. Factors associated with recalled vaccine uptake were assessed by multivariate logistic regression.

RESULTS

A total of 192 RA patients completed the survey, 134 (70%) of whom were women and 90 (47%) were aged ≥ 65 years. Sixty-seven patients (35%) received conventional disease-modifying anti-rheumatic drugs (cDMARDs) and 125 (65%) combination therapy with biological disease-modifying anti-rheumatic drugs (bDMARDs). Self-reported uptake of vaccination against seasonal influenza ever was 59% overall; 57% among patients receiving cDMARDs and 61% in patients receiving bDMARDs. Self-reported vaccine uptake against pneumococcal diseases was only 6% overall. Older age, educational level, and information and recommendation by a specialist or general physician were positively associated with influenza vaccine uptake, while there was no significant difference in vaccine uptake according to RA treatment type. Reasons for not being vaccinated included fear of adverse effects, lack of information and recommendation, and perception of good health.

CONCLUSION

We observed a low prevalence of influenza and in particular of pneumococcal vaccinations among RA patients receiving immunosuppressive drugs, with no difference in coverage according to type of RA therapy. More population-specific evidence to support recommendations is required to increase awareness among patients and physicians.

Authors+Show Affiliations

a Department of Infectious Diseases , Odense University Hospital , Odense , Denmark. b Institute of Clinical Research , University of Southern Denmark , Odense , Denmark. c OPEN, Odense Patient data Explorative Network , Odense University Hospital , Odense , Denmark.d Department of Rheumatology , Odense University Hospital , Odense , Denmark.e Department of Rheumatology , King Christian 10th Hospital for Rheumatic Diseases , Graasten , Denmark. f Institute of Regional Research , University of Southern Denmark , Odense , Denmark.a Department of Infectious Diseases , Odense University Hospital , Odense , Denmark.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28145151

Citation

Nguyen, Mtt, et al. "Factors Associated With Influenza and Pneumococcal Vaccine Uptake Among Rheumatoid Arthritis Patients in Denmark Invited to Participate in a Pneumococcal Vaccine Trial (Immunovax_RA)." Scandinavian Journal of Rheumatology, vol. 46, no. 6, 2017, pp. 446-453.
Nguyen M, Lindegaard H, Hendricks O, et al. Factors associated with influenza and pneumococcal vaccine uptake among rheumatoid arthritis patients in Denmark invited to participate in a pneumococcal vaccine trial (Immunovax_RA). Scand J Rheumatol. 2017;46(6):446-453.
Nguyen, M., Lindegaard, H., Hendricks, O., & Friis-Møller, N. (2017). Factors associated with influenza and pneumococcal vaccine uptake among rheumatoid arthritis patients in Denmark invited to participate in a pneumococcal vaccine trial (Immunovax_RA). Scandinavian Journal of Rheumatology, 46(6), 446-453. https://doi.org/10.1080/03009742.2016.1242774
Nguyen M, et al. Factors Associated With Influenza and Pneumococcal Vaccine Uptake Among Rheumatoid Arthritis Patients in Denmark Invited to Participate in a Pneumococcal Vaccine Trial (Immunovax_RA). Scand J Rheumatol. 2017;46(6):446-453. PubMed PMID: 28145151.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Factors associated with influenza and pneumococcal vaccine uptake among rheumatoid arthritis patients in Denmark invited to participate in a pneumococcal vaccine trial (Immunovax_RA). AU - Nguyen,Mtt, AU - Lindegaard,H, AU - Hendricks,O, AU - Friis-Møller,N, Y1 - 2017/02/01/ PY - 2017/2/2/pubmed PY - 2017/11/8/medline PY - 2017/2/2/entrez SP - 446 EP - 453 JF - Scandinavian journal of rheumatology JO - Scand J Rheumatol VL - 46 IS - 6 N2 - OBJECTIVE: This study investigates predictors of influenza and pneumococcal vaccine coverage among rheumatoid arthritis (RA) patients, and explores possible differences according to type of RA therapy. METHOD: RA patients from two clinics in the region of Southern Denmark were informed about the survey during scheduled follow-up visits. The questionnaire included questions concerning previous influenza and pneumococcal vaccine uptake, attitudes about vaccination, and socio-demographic factors. Factors associated with recalled vaccine uptake were assessed by multivariate logistic regression. RESULTS: A total of 192 RA patients completed the survey, 134 (70%) of whom were women and 90 (47%) were aged ≥ 65 years. Sixty-seven patients (35%) received conventional disease-modifying anti-rheumatic drugs (cDMARDs) and 125 (65%) combination therapy with biological disease-modifying anti-rheumatic drugs (bDMARDs). Self-reported uptake of vaccination against seasonal influenza ever was 59% overall; 57% among patients receiving cDMARDs and 61% in patients receiving bDMARDs. Self-reported vaccine uptake against pneumococcal diseases was only 6% overall. Older age, educational level, and information and recommendation by a specialist or general physician were positively associated with influenza vaccine uptake, while there was no significant difference in vaccine uptake according to RA treatment type. Reasons for not being vaccinated included fear of adverse effects, lack of information and recommendation, and perception of good health. CONCLUSION: We observed a low prevalence of influenza and in particular of pneumococcal vaccinations among RA patients receiving immunosuppressive drugs, with no difference in coverage according to type of RA therapy. More population-specific evidence to support recommendations is required to increase awareness among patients and physicians. SN - 1502-7732 UR - https://www.unboundmedicine.com/medline/citation/28145151/Factors_associated_with_influenza_and_pneumococcal_vaccine_uptake_among_rheumatoid_arthritis_patients_in_Denmark_invited_to_participate_in_a_pneumococcal_vaccine_trial__Immunovax_RA__ L2 - https://www.tandfonline.com/doi/full/10.1080/03009742.2016.1242774 DB - PRIME DP - Unbound Medicine ER -