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Dermoscopic features of nail psoriasis treated with biologics.
J Dermatol. 2017 May; 44(5):538-541.JD

Abstract

Although psoriatic nail lesions are small, they cause considerable discomfort for patients and adversely affect quality of life. Few studies have evaluated the dermoscopic features of psoriatic nails. The aim of this study was to clarify the dermoscopic features of nail psoriasis and identify those that reflect psoriatic activity. During biologic treatment of psoriasis, six patients with psoriatic nails twice underwent dermoscopic examination, with an interval of 17-42 weeks. We used the modified Nail Psoriasis Severity Index score and Psoriasis Area and Severity Index score to identify and assess dermoscopic features. We identified 10 dermoscopic findings, of which disappearance of diffuse scaling of the nail plate, transverse step-like notches and splinter hemorrhages of the nail bed, and appearance of erythematous borders of the onycholytic area were associated with improvement in Psoriasis Area and Severity Index score. Dermoscopy can detect nail changes during psoriasis treatment and should be used to evaluate treatment success.

Authors+Show Affiliations

Department of Dermatology, School of Medicine, Faculty of Medicine, Toho University, Tokyo, Japan.Department of Dermatology, School of Medicine, Faculty of Medicine, Toho University, Tokyo, Japan.Department of Dermatology, School of Medicine, Faculty of Medicine, Toho University, Tokyo, Japan.Department of Dermatology, School of Medicine, Faculty of Medicine, Toho University, Tokyo, Japan.Department of Dermatology, School of Medicine, Faculty of Medicine, Toho University, Tokyo, Japan.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28150346

Citation

Hashimoto, Yuki, et al. "Dermoscopic Features of Nail Psoriasis Treated With Biologics." The Journal of Dermatology, vol. 44, no. 5, 2017, pp. 538-541.
Hashimoto Y, Uyama M, Takada Y, et al. Dermoscopic features of nail psoriasis treated with biologics. J Dermatol. 2017;44(5):538-541.
Hashimoto, Y., Uyama, M., Takada, Y., Yoshida, K., & Ishiko, A. (2017). Dermoscopic features of nail psoriasis treated with biologics. The Journal of Dermatology, 44(5), 538-541. https://doi.org/10.1111/1346-8138.13752
Hashimoto Y, et al. Dermoscopic Features of Nail Psoriasis Treated With Biologics. J Dermatol. 2017;44(5):538-541. PubMed PMID: 28150346.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dermoscopic features of nail psoriasis treated with biologics. AU - Hashimoto,Yuki, AU - Uyama,Miki, AU - Takada,Yuko, AU - Yoshida,Kenji, AU - Ishiko,Akira, Y1 - 2017/02/02/ PY - 2016/08/02/received PY - 2016/11/30/accepted PY - 2017/2/6/pubmed PY - 2018/3/15/medline PY - 2017/2/3/entrez KW - Nail Psoriasis Severity Index score KW - biologics KW - dermoscopic features KW - dermoscopy KW - nail psoriasis SP - 538 EP - 541 JF - The Journal of dermatology JO - J. Dermatol. VL - 44 IS - 5 N2 - Although psoriatic nail lesions are small, they cause considerable discomfort for patients and adversely affect quality of life. Few studies have evaluated the dermoscopic features of psoriatic nails. The aim of this study was to clarify the dermoscopic features of nail psoriasis and identify those that reflect psoriatic activity. During biologic treatment of psoriasis, six patients with psoriatic nails twice underwent dermoscopic examination, with an interval of 17-42 weeks. We used the modified Nail Psoriasis Severity Index score and Psoriasis Area and Severity Index score to identify and assess dermoscopic features. We identified 10 dermoscopic findings, of which disappearance of diffuse scaling of the nail plate, transverse step-like notches and splinter hemorrhages of the nail bed, and appearance of erythematous borders of the onycholytic area were associated with improvement in Psoriasis Area and Severity Index score. Dermoscopy can detect nail changes during psoriasis treatment and should be used to evaluate treatment success. SN - 1346-8138 UR - https://www.unboundmedicine.com/medline/citation/28150346/Dermoscopic_features_of_nail_psoriasis_treated_with_biologics_ L2 - https://doi.org/10.1111/1346-8138.13752 DB - PRIME DP - Unbound Medicine ER -