TY - JOUR T1 - Danggui Buxue Tang (Astragali Radix and Angelicae Sinensis Radix) for menopausal symptoms: A review. AU - Lin,Huang Q, AU - Gong,Amy G W, AU - Wang,Huai Y, AU - Duan,Ran, AU - Dong,Tina T X, AU - Zhao,Kui J, AU - Tsim,Karl W K, Y1 - 2017/02/02/ PY - 2016/09/14/received PY - 2017/01/21/revised PY - 2017/01/21/accepted PY - 2017/2/7/pubmed PY - 2017/7/15/medline PY - 2017/2/7/entrez KW - Angelicae Sinensis Radix KW - Astragali Radix KW - Danggui Buxue Tang KW - Traditional chinese medicine SP - 205 EP - 210 JF - Journal of ethnopharmacology JO - J Ethnopharmacol VL - 199 N2 - BACKGROUND: Traditional Chinese medicine (TCM) has contributed greatly to human health in past several thousand years. Today, the development of TCM is facing two obstacles: (i) quality control of herbal extract; and (ii) action mechanisms not known. OBJECTIVES: Among thousands of complex TCM formulations, Danggui Buxue Tang (DBT) is the simplest one. DBT is used to treat ailments in women and contains only two herbs, Astragali Radix (Huangqi; AR) and Angelicae Sinensis Radix (Danggui; ASR). The weight ratio of AR to ASR in DBT must be 5:1, as stipulated in AD 1247. By using DBT as a model formula, we develop a strategy to reveal the complexity of a traditional TCM formula. RESULTS: There are 3 levels of research directions: (i) the preparation of DBT and its rationale behind; (ii) the traditional theory of DBT is elucidated by chemical and biological determinations; and (iii) the action mechanisms of DBT are revealed. CONCLUSION: Through the chemical, biological, genomic and proteomic studies, a possible direction in resolving the preparation mythologies, pharmacological and mechanistic analyses of a TCM decoction is being proposed here. SN - 1872-7573 UR - https://www.unboundmedicine.com/medline/citation/28163116/Danggui_Buxue_Tang__Astragali_Radix_and_Angelicae_Sinensis_Radix__for_menopausal_symptoms:_A_review_ DB - PRIME DP - Unbound Medicine ER -