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[Neuroborreliosis - Diagnostics, treatment and course].
Nervenarzt. 2017 Apr; 88(4):419-431.N

Abstract

Lyme neuroborreliosis is a tick-borne infectious disease caused by the spirochete bacterium Borrelia burgdorferi sensu lato. Clinical manifestations are classified as early and late Lyme neuroborreliosis. Early manifestations are much more common than late manifestations. Serological testing should only be performed when typical neurological symptoms are present because false positive results are common due to a high seroprevalence in the population. Cerebrospinal fluid (CSF) analysis should be performed if Lyme neuroborreliosis is suspected. A systematic review found similar effects of beta-lactam antibiotics and doxycycline regarding the outcome of neurological symptoms and adverse effects. The prognosis after antibiotic treatment is usually favorable and residual symptoms can rarely persist. Impairments in quality of life, fatigue, depression and cognitive impairment are not more frequent in patients after treatment of Lyme neuroborreliosis than in the normal healthy population.

Authors+Show Affiliations

Abteilung für Neurologie und Neurophysiologie, Universitätsklinikum Freiburg, Breisacher Str. 64, 79106, Freiburg, Deutschland. rick.dersch@uniklinik-freiburg.de.Abteilung für Neurologie und Neurophysiologie, Universitätsklinikum Freiburg, Breisacher Str. 64, 79106, Freiburg, Deutschland.

Pub Type(s)

Journal Article
Review
Systematic Review

Language

ger

PubMed ID

28175945

Citation

Dersch, R, and S Rauer. "[Neuroborreliosis - Diagnostics, Treatment and Course]." Der Nervenarzt, vol. 88, no. 4, 2017, pp. 419-431.
Dersch R, Rauer S. [Neuroborreliosis - Diagnostics, treatment and course]. Nervenarzt. 2017;88(4):419-431.
Dersch, R., & Rauer, S. (2017). [Neuroborreliosis - Diagnostics, treatment and course]. Der Nervenarzt, 88(4), 419-431. https://doi.org/10.1007/s00115-016-0263-1
Dersch R, Rauer S. [Neuroborreliosis - Diagnostics, Treatment and Course]. Nervenarzt. 2017;88(4):419-431. PubMed PMID: 28175945.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Neuroborreliosis - Diagnostics, treatment and course]. AU - Dersch,R, AU - Rauer,S, PY - 2017/2/9/pubmed PY - 2017/11/14/medline PY - 2017/2/9/entrez KW - Evidence-based medicine KW - Lyme disease KW - Lyme neuroborreliosis KW - Quality of life KW - Treatment SP - 419 EP - 431 JF - Der Nervenarzt JO - Nervenarzt VL - 88 IS - 4 N2 - Lyme neuroborreliosis is a tick-borne infectious disease caused by the spirochete bacterium Borrelia burgdorferi sensu lato. Clinical manifestations are classified as early and late Lyme neuroborreliosis. Early manifestations are much more common than late manifestations. Serological testing should only be performed when typical neurological symptoms are present because false positive results are common due to a high seroprevalence in the population. Cerebrospinal fluid (CSF) analysis should be performed if Lyme neuroborreliosis is suspected. A systematic review found similar effects of beta-lactam antibiotics and doxycycline regarding the outcome of neurological symptoms and adverse effects. The prognosis after antibiotic treatment is usually favorable and residual symptoms can rarely persist. Impairments in quality of life, fatigue, depression and cognitive impairment are not more frequent in patients after treatment of Lyme neuroborreliosis than in the normal healthy population. SN - 1433-0407 UR - https://www.unboundmedicine.com/medline/citation/28175945/[Neuroborreliosis___Diagnostics_treatment_and_course]_ L2 - https://dx.doi.org/10.1007/s00115-016-0263-1 DB - PRIME DP - Unbound Medicine ER -