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An extramedullary plasmacytoma in the kidney of a 14-year-old girl: Case report and review of the literature.
Medicine (Baltimore). 2017 Feb; 96(6):e6092.M

Abstract

RATIONALE

Extramedullary plasmacytoma (EMP) a rare plasma cell disorder and is frequently associated with plasma cell bone marrow infiltration. Most EMPs involve mucosal lymphoid tissue, especially in the nasopharyngeal area, respiratory tract, and head and neck region. Primary involvement of the kidney is exceedingly rare.

PATIENT CONCERNS

A 14-year-old girl was admitted in our hospital with intermittent right upper quadrant pain for 1 month and recent (1 day) progressive deterioration. There was a mass found by ultrasonography in the right kidney and subsequent abdominal computed tomography scan revealed a 3 cm mass within the right kidney.

DIAGNOSES

Pathology revealed typical histology of plasmacytoma and immunohistochemistry revealed the expression of CD138, CD45, vimentin, and Kappa light chain.

INTERVENTIONS

The patient successfully underwent radical nephrectomy with an uneventful recovery. She received no chemotherapy or radiotherapy after surgery.

OUTCOMES

There was no recurrence or metastasis during a 22-month follow-up.

LESSONS

Our case study demonstrated that renal EMP with a relatively indolent clinical course, if detected at an early stage, can be treated by radical nephrectomy without adjuvant therapy. Generally, the clinical outcome and prognosis of EMP are favorable.

Authors+Show Affiliations

aDepartment of Urology, Affiliated Hospital of Binzhou Medical University, Binzhou bDepartment of Urology, Second Hospital of Tianjin Medical University, Tianjin Institute of Urology, Tianjin, China.No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

28178171

Citation

Mei, Yan-Hui, et al. "An Extramedullary Plasmacytoma in the Kidney of a 14-year-old Girl: Case Report and Review of the Literature." Medicine, vol. 96, no. 6, 2017, pp. e6092.
Mei YH, Yu JP, Li G. An extramedullary plasmacytoma in the kidney of a 14-year-old girl: Case report and review of the literature. Medicine (Baltimore). 2017;96(6):e6092.
Mei, Y. H., Yu, J. P., & Li, G. (2017). An extramedullary plasmacytoma in the kidney of a 14-year-old girl: Case report and review of the literature. Medicine, 96(6), e6092. https://doi.org/10.1097/MD.0000000000006092
Mei YH, Yu JP, Li G. An Extramedullary Plasmacytoma in the Kidney of a 14-year-old Girl: Case Report and Review of the Literature. Medicine (Baltimore). 2017;96(6):e6092. PubMed PMID: 28178171.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - An extramedullary plasmacytoma in the kidney of a 14-year-old girl: Case report and review of the literature. AU - Mei,Yan-Hui, AU - Yu,Jian-Peng, AU - Li,Gang, PY - 2017/2/9/entrez PY - 2017/2/9/pubmed PY - 2017/2/28/medline SP - e6092 EP - e6092 JF - Medicine JO - Medicine (Baltimore) VL - 96 IS - 6 N2 - RATIONALE: Extramedullary plasmacytoma (EMP) a rare plasma cell disorder and is frequently associated with plasma cell bone marrow infiltration. Most EMPs involve mucosal lymphoid tissue, especially in the nasopharyngeal area, respiratory tract, and head and neck region. Primary involvement of the kidney is exceedingly rare. PATIENT CONCERNS: A 14-year-old girl was admitted in our hospital with intermittent right upper quadrant pain for 1 month and recent (1 day) progressive deterioration. There was a mass found by ultrasonography in the right kidney and subsequent abdominal computed tomography scan revealed a 3 cm mass within the right kidney. DIAGNOSES: Pathology revealed typical histology of plasmacytoma and immunohistochemistry revealed the expression of CD138, CD45, vimentin, and Kappa light chain. INTERVENTIONS: The patient successfully underwent radical nephrectomy with an uneventful recovery. She received no chemotherapy or radiotherapy after surgery. OUTCOMES: There was no recurrence or metastasis during a 22-month follow-up. LESSONS: Our case study demonstrated that renal EMP with a relatively indolent clinical course, if detected at an early stage, can be treated by radical nephrectomy without adjuvant therapy. Generally, the clinical outcome and prognosis of EMP are favorable. SN - 1536-5964 UR - https://www.unboundmedicine.com/medline/citation/28178171/An_extramedullary_plasmacytoma_in_the_kidney_of_a_14_year_old_girl:_Case_report_and_review_of_the_literature_ L2 - http://dx.doi.org/10.1097/MD.0000000000006092 DB - PRIME DP - Unbound Medicine ER -