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Dietary zinc and iron intake and risk of depression: A meta-analysis.
Psychiatry Res. 2017 May; 251:41-47.PR

Abstract

The associations between dietary zinc and iron intake and risk of depression remain controversial. Thus, we carried out a meta-analysis to evaluate these associations. A systematic search was performed in PubMed, Embase, Web of Science, Chinese National Knowledge Infrastructure (CNKI) and Wanfang databases for relevant studies up to January 2017. Pooled relative risks (RRs) with 95% confidence intervals (CIs) were calculated using a random effects model. A total of 9 studies for dietary zinc intake and 3 studies for dietary iron intake were finally included in present meta-analysis. The pooled RRs with 95% CIs of depression for the highest versus lowest dietary zinc and iron intake were 0.67 (95% CI: 0.58-0.76) and 0.57 (95% CI: 0.34-0.95), respectively. In subgroup analysis by study design, the inverse association between dietary zinc intake and risk of depression remained significant in the cohort studies and cross-sectional studies. The pooled RRs (95% CIs) for depression did not substantially change in the influence analysis and subgroup analysis by adjustment for body mass index (BMI). The present meta-analysis indicates inverse associations between dietary zinc and iron intake and risk of depression.

Authors+Show Affiliations

Department of Epidemiology and Health Statistics, the School of Public Health of Qingdao University, 38 Dengzhou Road, Qingdao, Shandong 266021, People's Republic of China.Department of Epidemiology and Health Statistics, the School of Public Health of Qingdao University, 38 Dengzhou Road, Qingdao, Shandong 266021, People's Republic of China.Department of Epidemiology and Health Statistics, the School of Public Health of Qingdao University, 38 Dengzhou Road, Qingdao, Shandong 266021, People's Republic of China.Department of Epidemiology and Health Statistics, the School of Public Health of Qingdao University, 38 Dengzhou Road, Qingdao, Shandong 266021, People's Republic of China. Electronic address: zhangdf1961@126.com.

Pub Type(s)

Journal Article
Meta-Analysis
Review

Language

eng

PubMed ID

28189077

Citation

Li, Zongyao, et al. "Dietary Zinc and Iron Intake and Risk of Depression: a Meta-analysis." Psychiatry Research, vol. 251, 2017, pp. 41-47.
Li Z, Li B, Song X, et al. Dietary zinc and iron intake and risk of depression: A meta-analysis. Psychiatry Res. 2017;251:41-47.
Li, Z., Li, B., Song, X., & Zhang, D. (2017). Dietary zinc and iron intake and risk of depression: A meta-analysis. Psychiatry Research, 251, 41-47. https://doi.org/10.1016/j.psychres.2017.02.006
Li Z, et al. Dietary Zinc and Iron Intake and Risk of Depression: a Meta-analysis. Psychiatry Res. 2017;251:41-47. PubMed PMID: 28189077.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary zinc and iron intake and risk of depression: A meta-analysis. AU - Li,Zongyao, AU - Li,Bingrong, AU - Song,Xingxing, AU - Zhang,Dongfeng, Y1 - 2017/02/03/ PY - 2016/10/17/received PY - 2017/01/22/revised PY - 2017/02/02/accepted PY - 2017/2/12/pubmed PY - 2017/11/29/medline PY - 2017/2/12/entrez KW - Depression KW - Iron KW - Meta-analysis KW - Zinc SP - 41 EP - 47 JF - Psychiatry research JO - Psychiatry Res VL - 251 N2 - The associations between dietary zinc and iron intake and risk of depression remain controversial. Thus, we carried out a meta-analysis to evaluate these associations. A systematic search was performed in PubMed, Embase, Web of Science, Chinese National Knowledge Infrastructure (CNKI) and Wanfang databases for relevant studies up to January 2017. Pooled relative risks (RRs) with 95% confidence intervals (CIs) were calculated using a random effects model. A total of 9 studies for dietary zinc intake and 3 studies for dietary iron intake were finally included in present meta-analysis. The pooled RRs with 95% CIs of depression for the highest versus lowest dietary zinc and iron intake were 0.67 (95% CI: 0.58-0.76) and 0.57 (95% CI: 0.34-0.95), respectively. In subgroup analysis by study design, the inverse association between dietary zinc intake and risk of depression remained significant in the cohort studies and cross-sectional studies. The pooled RRs (95% CIs) for depression did not substantially change in the influence analysis and subgroup analysis by adjustment for body mass index (BMI). The present meta-analysis indicates inverse associations between dietary zinc and iron intake and risk of depression. SN - 1872-7123 UR - https://www.unboundmedicine.com/medline/citation/28189077/Dietary_zinc_and_iron_intake_and_risk_of_depression:_A_meta_analysis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0165-1781(16)31774-7 DB - PRIME DP - Unbound Medicine ER -