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MELTUMP: how to manage these lesions in the clinical routine.
G Ital Dermatol Venereol 2017; 152(3):266-269GI

Abstract

Although most melanocytic lesions can be diagnosed by histopathologists as benign or malignant with high confidence, a subset of morphologically ambiguous lesions does exist and still represents a significant problem for pathologists. These lesions have been defined as MELTUMP, i.e. melanocytic tumors of uncertain malignant potential. MELTUMP could be considered as a large cauldron in which melanocytic lesions with equivocal morphologic features fall into, including most benign lesions and a minority of melanomas, unfortunately recognizable only a posteriori for their unfavorable outcome. As a consequence of the lack of uniformity in the biologic behavior of melanocytic lesions belonging to the heterogeneous subset of MELTUMP, confusion and lack of agreement in the management of these difficult lesions is increasingly growing up. As most MELTUMP have a favorable prognosis we recommend a conservative approach, avoiding over treatment for this group of lesions.

Authors+Show Affiliations

Dermatology Unit, L. Vanvitelli University, Naples, Italy - piccolo.vincenzo@gmail.com.Dermatology Unit, L. Vanvitelli University, Naples, Italy. Dermatology and Skin Cancer Unit, Arcispedale S. Maria Nuova Institute for Research and Care, Reggio Emilia, Italy.First Department of Dermatology, Aristotle University, Thessaloniki, Greece.Department of Anesthesiology, Surgery and Emergency, L. Vanvitelli University, Naples, Italy.Anatomic Pathology Unit, General Hospital of Macerata, Macerata, Italy.Dermatology Unit, L. Vanvitelli University, Naples, Italy.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

28195450

Citation

Piccolo, Vincenzo, et al. "MELTUMP: How to Manage These Lesions in the Clinical Routine." Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Societa Italiana Di Dermatologia E Sifilografia, vol. 152, no. 3, 2017, pp. 266-269.
Piccolo V, Moscarella E, Lallas A, et al. MELTUMP: how to manage these lesions in the clinical routine. G Ital Dermatol Venereol. 2017;152(3):266-269.
Piccolo, V., Moscarella, E., Lallas, A., Alfano, R., Ferrara, G., & Argenziano, G. (2017). MELTUMP: how to manage these lesions in the clinical routine. Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Societa Italiana Di Dermatologia E Sifilografia, 152(3), pp. 266-269. doi:10.23736/S0392-0488.17.05569-9.
Piccolo V, et al. MELTUMP: How to Manage These Lesions in the Clinical Routine. G Ital Dermatol Venereol. 2017;152(3):266-269. PubMed PMID: 28195450.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - MELTUMP: how to manage these lesions in the clinical routine. AU - Piccolo,Vincenzo, AU - Moscarella,Elvira, AU - Lallas,Aimilios, AU - Alfano,Roberto, AU - Ferrara,Gerardo, AU - Argenziano,Giuseppe, Y1 - 2017/02/14/ PY - 2017/2/15/pubmed PY - 2017/10/20/medline PY - 2017/2/15/entrez SP - 266 EP - 269 JF - Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia JO - G Ital Dermatol Venereol VL - 152 IS - 3 N2 - Although most melanocytic lesions can be diagnosed by histopathologists as benign or malignant with high confidence, a subset of morphologically ambiguous lesions does exist and still represents a significant problem for pathologists. These lesions have been defined as MELTUMP, i.e. melanocytic tumors of uncertain malignant potential. MELTUMP could be considered as a large cauldron in which melanocytic lesions with equivocal morphologic features fall into, including most benign lesions and a minority of melanomas, unfortunately recognizable only a posteriori for their unfavorable outcome. As a consequence of the lack of uniformity in the biologic behavior of melanocytic lesions belonging to the heterogeneous subset of MELTUMP, confusion and lack of agreement in the management of these difficult lesions is increasingly growing up. As most MELTUMP have a favorable prognosis we recommend a conservative approach, avoiding over treatment for this group of lesions. SN - 1827-1820 UR - https://www.unboundmedicine.com/medline/citation/28195450/MELTUMP:_how_to_manage_these_lesions_in_the_clinical_routine_ L2 - http://www.minervamedica.it/index2.t?show=R23Y2017N03A0266 DB - PRIME DP - Unbound Medicine ER -