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Outcomes of endovascular and open surgical repair of ruptured abdominal aortic aneurysms in elderly patients.
J Vasc Surg. 2017 07; 66(1):64-70.JV

Abstract

BACKGROUND

Endovascular aneurysm repair (EVAR) is becoming the preferred treatment modality for patients with a ruptured abdominal aortic aneurysm (rAAA). Although the survival advantage of EVAR over open aortic repair (OAR) has been shown in some studies, it is unclear whether this benefit extends to elderly patients. We sought to evaluate the outcomes of rAAA repair in octogenarians.

METHODS

We reviewed the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) data set (2005-2014) to identify patients older than 80 years who were treated with EVAR and OAR for rAAA. Procedural trends were evaluated during the course of the study period. Perioperative outcomes including mortality, morbidity, and hospital length of stay (LOS) were compared. Multivariable regression models were used to identify predictors of perioperative mortality and morbidity.

RESULTS

Among 1048 elderly patients who underwent rAAA repair, 450 (43%) and 598 (57%) were treated with EVAR and OAR, respectively. The use of EVAR to treat rAAA had increased significantly in this population of patients (0% in 2005 vs 56% in 2014; P < .001). The overall 30-day mortality rate among octogenarians was 41%. The mortality rate was significantly higher among those treated with OAR compared with EVAR (47% vs 33%; P < .001). Pneumonia (21% vs 10%; P < .001), reintubation (14% vs 9%; P < .001), and >48-hour ventilator dependence (43% vs 21%; P < .001) were significantly higher in patients undergoing OAR. Hospital LOS (13 vs 10 days; P < .001) was also longer in the OAR cohort. Compared with EVAR, OAR was independently predictive of 30-day mortality (adjusted odds ratio [AOR], 1.7; 95% confidence interval [CI], 1.3-2.2; P < .001), pneumonia (AOR, 2.4; 95% CI, 1.7-3.6; P < .001), >48-hour ventilator dependence (AOR, 2.5; 95% CI, 1.8-3.3; P < .001), and longer LOS (adjusted mean ratio, 1.4; 95% CI, 1.2-1.6; P < .001).

CONCLUSIONS

Elderly patients have significant but acceptable perioperative mortality and morbidity after rAAA repair. Use of endovascular repair in the elderly population has increased and is associated with better perioperative survival and 30-day outcomes compared with traditional open repair in this study.

Authors+Show Affiliations

Division of Vascular Surgery, University of Arizona, Tucson, Ariz. Electronic address: ttan@surgery.arizona.edu.Division of Vascular Surgery, University of Pittsburgh, Pittsburgh, Pa.Department of Biostatistics, Boston University School of Public Health, Boston, Mass.Department of Biostatistics, Boston University School of Public Health, Boston, Mass.Division of Vascular Surgery, Louisiana State University Health Sciences Center, Shreveport, La.Division of Vascular and Endovascular Surgery, Boston University School of Medicine, Boston, Mass.

Pub Type(s)

Comparative Study
Journal Article
Observational Study

Language

eng

PubMed ID

28216354

Citation

Tan, Tze-Woei, et al. "Outcomes of Endovascular and Open Surgical Repair of Ruptured Abdominal Aortic Aneurysms in Elderly Patients." Journal of Vascular Surgery, vol. 66, no. 1, 2017, pp. 64-70.
Tan TW, Eslami M, Rybin D, et al. Outcomes of endovascular and open surgical repair of ruptured abdominal aortic aneurysms in elderly patients. J Vasc Surg. 2017;66(1):64-70.
Tan, T. W., Eslami, M., Rybin, D., Doros, G., Zhang, W. W., & Farber, A. (2017). Outcomes of endovascular and open surgical repair of ruptured abdominal aortic aneurysms in elderly patients. Journal of Vascular Surgery, 66(1), 64-70. https://doi.org/10.1016/j.jvs.2016.10.119
Tan TW, et al. Outcomes of Endovascular and Open Surgical Repair of Ruptured Abdominal Aortic Aneurysms in Elderly Patients. J Vasc Surg. 2017;66(1):64-70. PubMed PMID: 28216354.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Outcomes of endovascular and open surgical repair of ruptured abdominal aortic aneurysms in elderly patients. AU - Tan,Tze-Woei, AU - Eslami,Mohammad, AU - Rybin,Denis, AU - Doros,Gheorghe, AU - Zhang,Wayne W, AU - Farber,Alik, PY - 2016/09/05/received PY - 2016/10/24/accepted PY - 2017/2/22/pubmed PY - 2017/7/14/medline PY - 2017/2/21/entrez SP - 64 EP - 70 JF - Journal of vascular surgery JO - J Vasc Surg VL - 66 IS - 1 N2 - BACKGROUND: Endovascular aneurysm repair (EVAR) is becoming the preferred treatment modality for patients with a ruptured abdominal aortic aneurysm (rAAA). Although the survival advantage of EVAR over open aortic repair (OAR) has been shown in some studies, it is unclear whether this benefit extends to elderly patients. We sought to evaluate the outcomes of rAAA repair in octogenarians. METHODS: We reviewed the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) data set (2005-2014) to identify patients older than 80 years who were treated with EVAR and OAR for rAAA. Procedural trends were evaluated during the course of the study period. Perioperative outcomes including mortality, morbidity, and hospital length of stay (LOS) were compared. Multivariable regression models were used to identify predictors of perioperative mortality and morbidity. RESULTS: Among 1048 elderly patients who underwent rAAA repair, 450 (43%) and 598 (57%) were treated with EVAR and OAR, respectively. The use of EVAR to treat rAAA had increased significantly in this population of patients (0% in 2005 vs 56% in 2014; P < .001). The overall 30-day mortality rate among octogenarians was 41%. The mortality rate was significantly higher among those treated with OAR compared with EVAR (47% vs 33%; P < .001). Pneumonia (21% vs 10%; P < .001), reintubation (14% vs 9%; P < .001), and >48-hour ventilator dependence (43% vs 21%; P < .001) were significantly higher in patients undergoing OAR. Hospital LOS (13 vs 10 days; P < .001) was also longer in the OAR cohort. Compared with EVAR, OAR was independently predictive of 30-day mortality (adjusted odds ratio [AOR], 1.7; 95% confidence interval [CI], 1.3-2.2; P < .001), pneumonia (AOR, 2.4; 95% CI, 1.7-3.6; P < .001), >48-hour ventilator dependence (AOR, 2.5; 95% CI, 1.8-3.3; P < .001), and longer LOS (adjusted mean ratio, 1.4; 95% CI, 1.2-1.6; P < .001). CONCLUSIONS: Elderly patients have significant but acceptable perioperative mortality and morbidity after rAAA repair. Use of endovascular repair in the elderly population has increased and is associated with better perioperative survival and 30-day outcomes compared with traditional open repair in this study. SN - 1097-6809 UR - https://www.unboundmedicine.com/medline/citation/28216354/Outcomes_of_endovascular_and_open_surgical_repair_of_ruptured_abdominal_aortic_aneurysms_in_elderly_patients_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0741-5214(16)31780-3 DB - PRIME DP - Unbound Medicine ER -