Tags

Type your tag names separated by a space and hit enter

Dominant factors affecting reproductive outcomes of fertility-desiring young women with intrauterine adhesions.
Arch Gynecol Obstet. 2017 Apr; 295(4):923-927.AG

Abstract

PURPOSE

To identify the dominant factors affecting reproductive outcomes of fertility-desiring young women with intrauterine adhesions (IUA) after hysteroscopic adhesiolysis.

METHODS

This prospective observational study included 104 cases of women with IUA. Logistic regression analysis was applied to analyze the value of the location and extent of adhesions, the number of previous uterine cavity surgery, menstrual patterns, and second look hysteroscopy time.

RESULTS

In the total 104 patients with IUA, 91 patients (87.5%) had a history of at least one previous uterine cavity surgery. Hypomenorrhoea and amenorrhoea were two most common presenting menstrual abnormalities occurring in 59 (56.7%) and 28 (26.9%) cases, respectively. The clinical pregnancy rate was 60.6% (63/104) and the live birth rate was 39.4% (41/104). Pregnancy rate was higher in patients having mild IUA (81.5%) as compared to moderate (61.3%) or severe type (20.0%) (p < 0.001). The bivariate and binary logistic regression analysis revealed that the location and extent of adhesions were the independent parameters related to the reproductive outcome after hysteroscopic adhesiolysis for fertility-desiring women with IUA (p = 0.011 and p = 0.003, respectively), but not the number of previous uterine cavity surgery, menstrual patterns, and second look hysteroscopy time (p = 0.232, p = 0.239 and p = 0.120, respectively).

CONCLUSION

The extent and location of IUA are the dominant factors affecting reproductive outcomes, which are possibly regarded as a potential predictor evaluating prognosis of IUA after hysteroscopic adhesiolysis.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 of Xiwu Road, Xi'an, People's Republic of China.Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 of Xiwu Road, Xi'an, People's Republic of China.Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 of Xiwu Road, Xi'an, People's Republic of China.Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 of Xiwu Road, Xi'an, People's Republic of China.Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 of Xiwu Road, Xi'an, People's Republic of China.Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Xi'an Jiaotong University, No. 157 of Xiwu Road, Xi'an, People's Republic of China. 494593127@qq.com.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28233115

Citation

Zhao, Jinyan, et al. "Dominant Factors Affecting Reproductive Outcomes of Fertility-desiring Young Women With Intrauterine Adhesions." Archives of Gynecology and Obstetrics, vol. 295, no. 4, 2017, pp. 923-927.
Zhao J, Chen Q, Cai D, et al. Dominant factors affecting reproductive outcomes of fertility-desiring young women with intrauterine adhesions. Arch Gynecol Obstet. 2017;295(4):923-927.
Zhao, J., Chen, Q., Cai, D., Duan, Z., Li, X., & Xue, X. (2017). Dominant factors affecting reproductive outcomes of fertility-desiring young women with intrauterine adhesions. Archives of Gynecology and Obstetrics, 295(4), 923-927. https://doi.org/10.1007/s00404-017-4314-z
Zhao J, et al. Dominant Factors Affecting Reproductive Outcomes of Fertility-desiring Young Women With Intrauterine Adhesions. Arch Gynecol Obstet. 2017;295(4):923-927. PubMed PMID: 28233115.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dominant factors affecting reproductive outcomes of fertility-desiring young women with intrauterine adhesions. AU - Zhao,Jinyan, AU - Chen,Qing, AU - Cai,Dongge, AU - Duan,Zhao, AU - Li,Xianghong, AU - Xue,Xiang, Y1 - 2017/02/23/ PY - 2016/10/24/received PY - 2017/02/01/accepted PY - 2017/2/25/pubmed PY - 2017/9/12/medline PY - 2017/2/25/entrez KW - Extent KW - IUA KW - Location KW - Reproductive outcome KW - Second look hysteroscopy SP - 923 EP - 927 JF - Archives of gynecology and obstetrics JO - Arch. Gynecol. Obstet. VL - 295 IS - 4 N2 - PURPOSE: To identify the dominant factors affecting reproductive outcomes of fertility-desiring young women with intrauterine adhesions (IUA) after hysteroscopic adhesiolysis. METHODS: This prospective observational study included 104 cases of women with IUA. Logistic regression analysis was applied to analyze the value of the location and extent of adhesions, the number of previous uterine cavity surgery, menstrual patterns, and second look hysteroscopy time. RESULTS: In the total 104 patients with IUA, 91 patients (87.5%) had a history of at least one previous uterine cavity surgery. Hypomenorrhoea and amenorrhoea were two most common presenting menstrual abnormalities occurring in 59 (56.7%) and 28 (26.9%) cases, respectively. The clinical pregnancy rate was 60.6% (63/104) and the live birth rate was 39.4% (41/104). Pregnancy rate was higher in patients having mild IUA (81.5%) as compared to moderate (61.3%) or severe type (20.0%) (p < 0.001). The bivariate and binary logistic regression analysis revealed that the location and extent of adhesions were the independent parameters related to the reproductive outcome after hysteroscopic adhesiolysis for fertility-desiring women with IUA (p = 0.011 and p = 0.003, respectively), but not the number of previous uterine cavity surgery, menstrual patterns, and second look hysteroscopy time (p = 0.232, p = 0.239 and p = 0.120, respectively). CONCLUSION: The extent and location of IUA are the dominant factors affecting reproductive outcomes, which are possibly regarded as a potential predictor evaluating prognosis of IUA after hysteroscopic adhesiolysis. SN - 1432-0711 UR - https://www.unboundmedicine.com/medline/citation/28233115/Dominant_factors_affecting_reproductive_outcomes_of_fertility_desiring_young_women_with_intrauterine_adhesions_ L2 - https://dx.doi.org/10.1007/s00404-017-4314-z DB - PRIME DP - Unbound Medicine ER -