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Fermentation of dietary fibre in the intestinal tract: comparison between man and rat.
Br J Nutr. 1986 May; 55(3):487-96.BJ

Abstract

1. The breakdown and faecal bulking capacity of dietary fibre preparations from wheat bran, apple, cabbage, carrot, and guar gum were compared in man and rat. 2. The degradation of the fibre showed good correlation between man and rat (r 0.99, regression coefficient 0.86). Wheat bran was the least well-digested, 66 and 59% of the neutral sugars being excreted in faeces of man and rat respectively. The breakdown of the fibre in apple, cabbage, carrot and guar gum was more complete and 4-29% of the neutral sugars were recovered in faeces. 3. The main dietary fibre constituents in each preparation were degraded to a similar extent in man and rat. The main dietary fibre constituents of apple, carrot, cabbage and guar gum were almost completely degraded. Of the xylose in wheat bran 45% (man) and 48% (rat) were recovered in faeces. However, the percentage excretion of glucose and arabinose from bran was higher in man. 4. A faecal glucan other than cellulose was identified in human faeces after guar gum, and has been provisionally identified as starch. No such glucan occurred in rat faeces. 5. A good correlation between the faecal bulking capacity in man and rat was seen (r 0.97, regression coefficient 0.56). Wheat bran had the best bulking capacity, while that of apple, cabbage, carrot and guar gum was less pronounced. Faecal bulking was inversely related to the amount of fibre which was water-soluble in each preparation. 6. It is concluded that this rat experimental model is useful for the prediction of fermentative breakdown and bulking capacity of dietary fibre in man. However, more comparative studies are needed to evaluate animal experiments regarding other physiological effects of dietary fibre.

Authors+Show Affiliations

Department of Food Chemistry, University of Lund, Sweden.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

2823868

Citation

Nyman, M, et al. "Fermentation of Dietary Fibre in the Intestinal Tract: Comparison Between Man and Rat." The British Journal of Nutrition, vol. 55, no. 3, 1986, pp. 487-96.
Nyman M, Asp NG, Cummings J, et al. Fermentation of dietary fibre in the intestinal tract: comparison between man and rat. Br J Nutr. 1986;55(3):487-96.
Nyman, M., Asp, N. G., Cummings, J., & Wiggins, H. (1986). Fermentation of dietary fibre in the intestinal tract: comparison between man and rat. The British Journal of Nutrition, 55(3), 487-96.
Nyman M, et al. Fermentation of Dietary Fibre in the Intestinal Tract: Comparison Between Man and Rat. Br J Nutr. 1986;55(3):487-96. PubMed PMID: 2823868.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fermentation of dietary fibre in the intestinal tract: comparison between man and rat. AU - Nyman,M, AU - Asp,N G, AU - Cummings,J, AU - Wiggins,H, PY - 1986/5/1/pubmed PY - 1986/5/1/medline PY - 1986/5/1/entrez SP - 487 EP - 96 JF - The British journal of nutrition JO - Br J Nutr VL - 55 IS - 3 N2 - 1. The breakdown and faecal bulking capacity of dietary fibre preparations from wheat bran, apple, cabbage, carrot, and guar gum were compared in man and rat. 2. The degradation of the fibre showed good correlation between man and rat (r 0.99, regression coefficient 0.86). Wheat bran was the least well-digested, 66 and 59% of the neutral sugars being excreted in faeces of man and rat respectively. The breakdown of the fibre in apple, cabbage, carrot and guar gum was more complete and 4-29% of the neutral sugars were recovered in faeces. 3. The main dietary fibre constituents in each preparation were degraded to a similar extent in man and rat. The main dietary fibre constituents of apple, carrot, cabbage and guar gum were almost completely degraded. Of the xylose in wheat bran 45% (man) and 48% (rat) were recovered in faeces. However, the percentage excretion of glucose and arabinose from bran was higher in man. 4. A faecal glucan other than cellulose was identified in human faeces after guar gum, and has been provisionally identified as starch. No such glucan occurred in rat faeces. 5. A good correlation between the faecal bulking capacity in man and rat was seen (r 0.97, regression coefficient 0.56). Wheat bran had the best bulking capacity, while that of apple, cabbage, carrot and guar gum was less pronounced. Faecal bulking was inversely related to the amount of fibre which was water-soluble in each preparation. 6. It is concluded that this rat experimental model is useful for the prediction of fermentative breakdown and bulking capacity of dietary fibre in man. However, more comparative studies are needed to evaluate animal experiments regarding other physiological effects of dietary fibre. SN - 0007-1145 UR - https://www.unboundmedicine.com/medline/citation/2823868/Fermentation_of_dietary_fibre_in_the_intestinal_tract:_comparison_between_man_and_rat_ DB - PRIME DP - Unbound Medicine ER -