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How do FODMAPs work?
J Gastroenterol Hepatol 2017; 32 Suppl 1:36-39JG

Abstract

Many patients report symptoms come on after eating, and experience with exclusion diets suggests that certainly poorly absorbed but rapidly fermentable carbohydrates may be responsible. While monomeric and short chain carbohydrate polymers exert osmotic forces and trap water in the small bowel with acceleration of transit, the longer polymer polymers such as inulin pass through the small bowel unaltered but are fermented in the colon where they may cause distension and symptoms. Recent developments in magnetic resonance imaging confirm the importance of fructose in stimulating small bowel water secretion and its negation by the presence of glucose. Fructans have no impact on the small intestine but cause colonic distension and symptoms including bloating.

Authors+Show Affiliations

Nottingham Digestive Diseases Biomedical Research Unit and Nottingham Digestive Diseases Centre, University of Nottingham and Queens Medical Centre, Nottingham, UK.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

28244663

Citation

Spiller, Robin. "How Do FODMAPs Work?" Journal of Gastroenterology and Hepatology, vol. 32 Suppl 1, 2017, pp. 36-39.
Spiller R. How do FODMAPs work? J Gastroenterol Hepatol. 2017;32 Suppl 1:36-39.
Spiller, R. (2017). How do FODMAPs work? Journal of Gastroenterology and Hepatology, 32 Suppl 1, pp. 36-39. doi:10.1111/jgh.13694.
Spiller R. How Do FODMAPs Work. J Gastroenterol Hepatol. 2017;32 Suppl 1:36-39. PubMed PMID: 28244663.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - How do FODMAPs work? A1 - Spiller,Robin, PY - 2016/11/21/accepted PY - 2017/3/1/entrez PY - 2017/3/1/pubmed PY - 2017/8/11/medline KW - MRI KW - colon KW - fructans KW - fructose KW - small intestine SP - 36 EP - 39 JF - Journal of gastroenterology and hepatology JO - J. Gastroenterol. Hepatol. VL - 32 Suppl 1 N2 - Many patients report symptoms come on after eating, and experience with exclusion diets suggests that certainly poorly absorbed but rapidly fermentable carbohydrates may be responsible. While monomeric and short chain carbohydrate polymers exert osmotic forces and trap water in the small bowel with acceleration of transit, the longer polymer polymers such as inulin pass through the small bowel unaltered but are fermented in the colon where they may cause distension and symptoms. Recent developments in magnetic resonance imaging confirm the importance of fructose in stimulating small bowel water secretion and its negation by the presence of glucose. Fructans have no impact on the small intestine but cause colonic distension and symptoms including bloating. SN - 1440-1746 UR - https://www.unboundmedicine.com/medline/citation/28244663/How_do_FODMAPs_work L2 - https://doi.org/10.1111/jgh.13694 DB - PRIME DP - Unbound Medicine ER -