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Relapsing bullous amyloidosis of the oral mucosa and acquired cutis laxa in a patient with multiple myeloma: a rare triple association.
Clin Exp Dermatol. 2017 Jun; 42(4):410-412.CE

Abstract

It is well known that primary systemic amyloidosis [light chain (AL) amyloidosis] is associated with hidden dyscrasia or multiple myeloma. Acquired cutis laxa (cutis laxa acquisita; CLA) has also been described in patients with plasma cell dyscrasias, including multiple myeloma. We report a case in which haemorrhagic oral bullae were the first sign of an undiagnosed primary systemic amyloidosis related to multiple myeloma IgG-λ and previously diagnosed CLA. There is only one report in literature of this rare triple association; however, in that case the patient did not have oral mucosal involvement or bullous amyloidosis.

Authors+Show Affiliations

Department of Dermatology, Hospital Universitario La Paz, Madrid, Spain.Department of Dermatopathology, Hospital Universitario La Paz, Madrid, Spain.Department of Dermatology, Hospital Universitario Infanta Sofia, San Sebastian de los Reyes, Madrid, Spain.Primary Care Medicine, Centro de salud Plaza del Ejercito, Valladolid, Spain.Primary Care Medicine, Centro de salud Plaza del Ejercito, Valladolid, Spain.Department of Dermatology, Hospital Universitario La Paz, Madrid, Spain.Department of Dermatology, Hospital Universitario La Paz, Madrid, Spain.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28247530

Citation

Gonzalez-Ramos, J, et al. "Relapsing Bullous Amyloidosis of the Oral Mucosa and Acquired Cutis Laxa in a Patient With Multiple Myeloma: a Rare Triple Association." Clinical and Experimental Dermatology, vol. 42, no. 4, 2017, pp. 410-412.
Gonzalez-Ramos J, Garrido-Gutiérrez C, González-Silva Y, et al. Relapsing bullous amyloidosis of the oral mucosa and acquired cutis laxa in a patient with multiple myeloma: a rare triple association. Clin Exp Dermatol. 2017;42(4):410-412.
Gonzalez-Ramos, J., Garrido-Gutiérrez, C., González-Silva, Y., Yébenes-Gregorio, L., Beato-Merino, M., Vidaurrázaga-Arcaya, C., & Herranz-Pinto, P. (2017). Relapsing bullous amyloidosis of the oral mucosa and acquired cutis laxa in a patient with multiple myeloma: a rare triple association. Clinical and Experimental Dermatology, 42(4), 410-412. https://doi.org/10.1111/ced.13084
Gonzalez-Ramos J, et al. Relapsing Bullous Amyloidosis of the Oral Mucosa and Acquired Cutis Laxa in a Patient With Multiple Myeloma: a Rare Triple Association. Clin Exp Dermatol. 2017;42(4):410-412. PubMed PMID: 28247530.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Relapsing bullous amyloidosis of the oral mucosa and acquired cutis laxa in a patient with multiple myeloma: a rare triple association. AU - Gonzalez-Ramos,J, AU - Garrido-Gutiérrez,C, AU - González-Silva,Y, AU - Yébenes-Gregorio,L, AU - Beato-Merino,M, AU - Vidaurrázaga-Arcaya,C, AU - Herranz-Pinto,P, Y1 - 2017/03/01/ PY - 2016/06/25/accepted PY - 2017/3/2/pubmed PY - 2017/3/2/medline PY - 2017/3/2/entrez SP - 410 EP - 412 JF - Clinical and experimental dermatology JO - Clin. Exp. Dermatol. VL - 42 IS - 4 N2 - It is well known that primary systemic amyloidosis [light chain (AL) amyloidosis] is associated with hidden dyscrasia or multiple myeloma. Acquired cutis laxa (cutis laxa acquisita; CLA) has also been described in patients with plasma cell dyscrasias, including multiple myeloma. We report a case in which haemorrhagic oral bullae were the first sign of an undiagnosed primary systemic amyloidosis related to multiple myeloma IgG-λ and previously diagnosed CLA. There is only one report in literature of this rare triple association; however, in that case the patient did not have oral mucosal involvement or bullous amyloidosis. SN - 1365-2230 UR - https://www.unboundmedicine.com/medline/citation/28247530/Relapsing_bullous_amyloidosis_of_the_oral_mucosa_and_acquired_cutis_laxa_in_a_patient_with_multiple_myeloma:_a_rare_triple_association_ L2 - https://doi.org/10.1111/ced.13084 DB - PRIME DP - Unbound Medicine ER -