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Asymptomatic and symptomatic urethral gonorrhoea in men who have sex with men attending a sexual health service.
Clin Microbiol Infect. 2017 Aug; 23(8):555-559.CM

Abstract

OBJECTIVES

Guidelines regarding whether men who have sex with men (MSM) without symptoms of urethritis should be screened for urethral gonorrhoea differ between countries. We examined the rate of asymptomatic urethral gonorrhoea in MSM using sensitive nucleic acid amplification testing.

METHODS

This study was conducted on consecutive MSM attending the Melbourne Sexual Health Centre between July 2015 and May 2016 for sexually transmitted infections screening. Gonorrhoea testing with the Aptima Combo 2 (AC2) assay was performed on all urine specimens obtained from MSM, whether symptoms of urethritis were present or not. Men were classified as having: typical discharge if they reported symptoms suggesting purulent discharge; other symptoms if they reported other symptoms of urethritis; and no symptoms if they reported no urethral symptoms.

RESULTS

During the study period, there were 7941 clinic visits by 5947 individual MSM with 7090 urine specimens obtained from 5497 individual MSM tested with the AC2 assay. Urethral gonorrhoea was detected in 242 urine specimens from 228 individual MSM. The majority (189/242, 78%, 95% CI 73-83) reported typical discharge, 27/242 (11%, 95% CI 8-16) reported other urethral symptoms, and 26/242 (11%, 95% CI 7-15) reported no symptoms on the day of presentation and testing. Among men with urethral gonorrhoea, the proportions with concurrent pharyngeal or rectal gonorrhoea were 32% (134/210) and 64% (74/235), respectively. The mean interval between last reported sexual contact and onset of typical urethral discharge, where present, was 3.9 days.

CONCLUSION

The findings from our study lend support to guidelines that recommend screening asymptomatic MSM for urethral gonorrhoea.

Authors+Show Affiliations

Melbourne Sexual Health Centre, Alfred Health, Melbourne, Vic., Australia; Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Vic., Australia. Electronic address: Jong@mshc.org.au.Melbourne Sexual Health Centre, Alfred Health, Melbourne, Vic., Australia.Microbiological Diagnostic Unit, Department of Microbiology and Immunology at the Peter Doherty Institution for Infection and Immunity, University of Melbourne, Melbourne, Vic., Australia.Melbourne Sexual Health Centre, Alfred Health, Melbourne, Vic., Australia; Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Vic., Australia.Melbourne Sexual Health Centre, Alfred Health, Melbourne, Vic., Australia; Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Vic., Australia.Microbiological Diagnostic Unit, Department of Microbiology and Immunology at the Peter Doherty Institution for Infection and Immunity, University of Melbourne, Melbourne, Vic., Australia.Microbiological Diagnostic Unit, Department of Microbiology and Immunology at the Peter Doherty Institution for Infection and Immunity, University of Melbourne, Melbourne, Vic., Australia.Melbourne Sexual Health Centre, Alfred Health, Melbourne, Vic., Australia.University of Melbourne, Faculty of Medicine, Dentistry and Health Sciences, Melbourne, Vic., Australia.Microbiological Diagnostic Unit, Department of Microbiology and Immunology at the Peter Doherty Institution for Infection and Immunity, University of Melbourne, Melbourne, Vic., Australia.Melbourne Sexual Health Centre, Alfred Health, Melbourne, Vic., Australia; Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Vic., Australia. Electronic address: MChen@mshc.org.au.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28257898

Citation

Ong, J J., et al. "Asymptomatic and Symptomatic Urethral Gonorrhoea in Men Who Have Sex With Men Attending a Sexual Health Service." Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, vol. 23, no. 8, 2017, pp. 555-559.
Ong JJ, Fethers K, Howden BP, et al. Asymptomatic and symptomatic urethral gonorrhoea in men who have sex with men attending a sexual health service. Clin Microbiol Infect. 2017;23(8):555-559.
Ong, J. J., Fethers, K., Howden, B. P., Fairley, C. K., Chow, E. P. F., Williamson, D. A., Petalotis, I., Aung, E., Kanhutu, K., De Petra, V., & Chen, M. Y. (2017). Asymptomatic and symptomatic urethral gonorrhoea in men who have sex with men attending a sexual health service. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 23(8), 555-559. https://doi.org/10.1016/j.cmi.2017.02.020
Ong JJ, et al. Asymptomatic and Symptomatic Urethral Gonorrhoea in Men Who Have Sex With Men Attending a Sexual Health Service. Clin Microbiol Infect. 2017;23(8):555-559. PubMed PMID: 28257898.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Asymptomatic and symptomatic urethral gonorrhoea in men who have sex with men attending a sexual health service. AU - Ong,J J, AU - Fethers,K, AU - Howden,B P, AU - Fairley,C K, AU - Chow,E P F, AU - Williamson,D A, AU - Petalotis,I, AU - Aung,E, AU - Kanhutu,K, AU - De Petra,V, AU - Chen,M Y, Y1 - 2017/02/28/ PY - 2016/12/05/received PY - 2017/02/16/revised PY - 2017/02/18/accepted PY - 2017/3/5/pubmed PY - 2018/4/3/medline PY - 2017/3/5/entrez KW - Gonorrhoea KW - Men who have sex with men KW - Screening KW - Sexually transmitted infection KW - Urethritis SP - 555 EP - 559 JF - Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases JO - Clin. Microbiol. Infect. VL - 23 IS - 8 N2 - OBJECTIVES: Guidelines regarding whether men who have sex with men (MSM) without symptoms of urethritis should be screened for urethral gonorrhoea differ between countries. We examined the rate of asymptomatic urethral gonorrhoea in MSM using sensitive nucleic acid amplification testing. METHODS: This study was conducted on consecutive MSM attending the Melbourne Sexual Health Centre between July 2015 and May 2016 for sexually transmitted infections screening. Gonorrhoea testing with the Aptima Combo 2 (AC2) assay was performed on all urine specimens obtained from MSM, whether symptoms of urethritis were present or not. Men were classified as having: typical discharge if they reported symptoms suggesting purulent discharge; other symptoms if they reported other symptoms of urethritis; and no symptoms if they reported no urethral symptoms. RESULTS: During the study period, there were 7941 clinic visits by 5947 individual MSM with 7090 urine specimens obtained from 5497 individual MSM tested with the AC2 assay. Urethral gonorrhoea was detected in 242 urine specimens from 228 individual MSM. The majority (189/242, 78%, 95% CI 73-83) reported typical discharge, 27/242 (11%, 95% CI 8-16) reported other urethral symptoms, and 26/242 (11%, 95% CI 7-15) reported no symptoms on the day of presentation and testing. Among men with urethral gonorrhoea, the proportions with concurrent pharyngeal or rectal gonorrhoea were 32% (134/210) and 64% (74/235), respectively. The mean interval between last reported sexual contact and onset of typical urethral discharge, where present, was 3.9 days. CONCLUSION: The findings from our study lend support to guidelines that recommend screening asymptomatic MSM for urethral gonorrhoea. SN - 1469-0691 UR - https://www.unboundmedicine.com/medline/citation/28257898/Asymptomatic_and_symptomatic_urethral_gonorrhoea_in_men_who_have_sex_with_men_attending_a_sexual_health_service_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1198-743X(17)30117-9 DB - PRIME DP - Unbound Medicine ER -