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Pituitary Adenoma Recurrence Suspected on Central Hyperthyroidism Despite Empty Sella and Confirmed by 68Ga-DOTA-TOC PET/CT.
Clin Nucl Med. 2017 Jun; 42(6):454-455.CN

Abstract

Thyrotropin-secreting pituitary adenomas are very rare tumors, known to present overexpression of somatostatin receptor subtype 2 and which may consequently demonstrate abnormal uptake on Ga-DOTA-TOC PET/CT. A 67-year-old woman with a history of operated pituitary macroadenoma presented with symptoms of hyperthyroidism including a large goiter. Her serum thyroid hormone levels were in favor of central hyperthyroidism. Pituitary MRI depicted an empty sella but visualized an ambiguous lesion centered on the left sphenoidal sinus. Complementary Ga-DOTA-TOC PET/CT finally demonstrated intense uptake by the sphenoidal lesion, confirming recurrence of the pituitary adenoma.

Authors+Show Affiliations

From the *Hôpital Tenon, AP-HP, Médecine Nucléaire, Paris; †Université Pierre et Marie Curie, Paris; and ‡Hôpital Saint-Antoine, AP-HP, Endocrinologie, Paris, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

28263215

Citation

Gauthé, Mathieu, et al. "Pituitary Adenoma Recurrence Suspected On Central Hyperthyroidism Despite Empty Sella and Confirmed By 68Ga-DOTA-TOC PET/CT." Clinical Nuclear Medicine, vol. 42, no. 6, 2017, pp. 454-455.
Gauthé M, Sarfati J, Bourcigaux N, et al. Pituitary Adenoma Recurrence Suspected on Central Hyperthyroidism Despite Empty Sella and Confirmed by 68Ga-DOTA-TOC PET/CT. Clin Nucl Med. 2017;42(6):454-455.
Gauthé, M., Sarfati, J., Bourcigaux, N., Christin-Maitre, S., Talbot, J. N., & Montravers, F. (2017). Pituitary Adenoma Recurrence Suspected on Central Hyperthyroidism Despite Empty Sella and Confirmed by 68Ga-DOTA-TOC PET/CT. Clinical Nuclear Medicine, 42(6), 454-455. https://doi.org/10.1097/RLU.0000000000001628
Gauthé M, et al. Pituitary Adenoma Recurrence Suspected On Central Hyperthyroidism Despite Empty Sella and Confirmed By 68Ga-DOTA-TOC PET/CT. Clin Nucl Med. 2017;42(6):454-455. PubMed PMID: 28263215.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pituitary Adenoma Recurrence Suspected on Central Hyperthyroidism Despite Empty Sella and Confirmed by 68Ga-DOTA-TOC PET/CT. AU - Gauthé,Mathieu, AU - Sarfati,Julie, AU - Bourcigaux,Nathalie, AU - Christin-Maitre,Sophie, AU - Talbot,Jean-Noël, AU - Montravers,Françoise, PY - 2017/3/7/pubmed PY - 2017/11/29/medline PY - 2017/3/7/entrez SP - 454 EP - 455 JF - Clinical nuclear medicine JO - Clin Nucl Med VL - 42 IS - 6 N2 - Thyrotropin-secreting pituitary adenomas are very rare tumors, known to present overexpression of somatostatin receptor subtype 2 and which may consequently demonstrate abnormal uptake on Ga-DOTA-TOC PET/CT. A 67-year-old woman with a history of operated pituitary macroadenoma presented with symptoms of hyperthyroidism including a large goiter. Her serum thyroid hormone levels were in favor of central hyperthyroidism. Pituitary MRI depicted an empty sella but visualized an ambiguous lesion centered on the left sphenoidal sinus. Complementary Ga-DOTA-TOC PET/CT finally demonstrated intense uptake by the sphenoidal lesion, confirming recurrence of the pituitary adenoma. SN - 1536-0229 UR - https://www.unboundmedicine.com/medline/citation/28263215/Pituitary_Adenoma_Recurrence_Suspected_on_Central_Hyperthyroidism_Despite_Empty_Sella_and_Confirmed_by_68Ga_DOTA_TOC_PET/CT_ L2 - https://dx.doi.org/10.1097/RLU.0000000000001628 DB - PRIME DP - Unbound Medicine ER -