Tags

Type your tag names separated by a space and hit enter

Effects of pre-pregnancy body mass index and gestational weight gain on neonatal birth weight.
J Zhejiang Univ Sci B. 2017 Mar.; 18(3):263-271.JZ

Abstract

To evaluate the effects of maternal pre-pregnancy body mass index (pre-BMI) and gestational weight gain (GWG) on neonatal birth weight (NBW) in the population of Chinese healthy pregnant women, attempting to guide weight control in pregnancy. A retrospective cohort study of 3772 Chinese women was conducted. The population was stratified by maternal pre-BMI categories as underweight (<18.5 kg/m2), normal weight (18.5-23.9 kg/m2), overweight (24.0-27.9 kg/m2), and obesity (≥28.0 kg/m2). The NBW differences were tested among the four groups, and then deeper associations among maternal pre-BMI, GWG, and NBW were investigated by multivariate analysis. NBW increased significantly with the increase of maternal pre-BMI level (P<0.05), except overweight to obesity (P>0.05). The multivariate analysis showed that both pre-BMI and GWG were positively correlated with NBW (P<0.05). Compared with normal pre-BMI, underweight predicted an increased odds ratio of small-for-gestational-age (SGA) and decreased odds ratio for macrosomia and large-for-gestational-age (LGA), and the results were opposite for overweight. With the increase of GWG, the risk of SGA decreased and the risks of macrosomia and LGA increased. In addition, in different pre-BMI categories, the effects of weight gain in the first trimester on NBW were different (P<0.05). NBW is positively affected by both maternal pre-BMI and GWG, extreme pre-BMI and GWG are both associated with increased risks of abnormal birth weight, and maternal pre-BMI may modify the effect of weight gain in each trimester on NBW. A valid GWG guideline for Chinese women is an urgent requirement, whereas existing recommendations seem to be not very suitable for the Chinese.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China.Maternal and Child Health Care Hospital of Ninghai County, Ningbo 315600, China.Department of Obstetrics and Gynecology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China.Department of Obstetrics and Gynecology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China.Department of Obstetrics and Gynecology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China.Department of Obstetrics and Gynecology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China.Department of Obstetrics and Gynecology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28271662

Citation

Du, Meng-Kai, et al. "Effects of Pre-pregnancy Body Mass Index and Gestational Weight Gain On Neonatal Birth Weight." Journal of Zhejiang University. Science. B, vol. 18, no. 3, 2017, pp. 263-271.
Du MK, Ge LY, Zhou ML, et al. Effects of pre-pregnancy body mass index and gestational weight gain on neonatal birth weight. J Zhejiang Univ Sci B. 2017;18(3):263-271.
Du, M. K., Ge, L. Y., Zhou, M. L., Ying, J., Qu, F., Dong, M. Y., & Chen, D. Q. (2017). Effects of pre-pregnancy body mass index and gestational weight gain on neonatal birth weight. Journal of Zhejiang University. Science. B, 18(3), 263-271. https://doi.org/10.1631/jzus.B1600204
Du MK, et al. Effects of Pre-pregnancy Body Mass Index and Gestational Weight Gain On Neonatal Birth Weight. J Zhejiang Univ Sci B. 2017;18(3):263-271. PubMed PMID: 28271662.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of pre-pregnancy body mass index and gestational weight gain on neonatal birth weight. AU - Du,Meng-Kai, AU - Ge,Li-Ya, AU - Zhou,Meng-Lin, AU - Ying,Jun, AU - Qu,Fan, AU - Dong,Min-Yue, AU - Chen,Dan-Qing, PY - 2017/3/9/entrez PY - 2017/3/9/pubmed PY - 2017/9/29/medline KW - Appropriate weight gain pattern KW - Gestational weight gain KW - Neonatal birth weight KW - Pre-pregnancy body mass index SP - 263 EP - 271 JF - Journal of Zhejiang University. Science. B JO - J Zhejiang Univ Sci B VL - 18 IS - 3 N2 - To evaluate the effects of maternal pre-pregnancy body mass index (pre-BMI) and gestational weight gain (GWG) on neonatal birth weight (NBW) in the population of Chinese healthy pregnant women, attempting to guide weight control in pregnancy. A retrospective cohort study of 3772 Chinese women was conducted. The population was stratified by maternal pre-BMI categories as underweight (<18.5 kg/m2), normal weight (18.5-23.9 kg/m2), overweight (24.0-27.9 kg/m2), and obesity (≥28.0 kg/m2). The NBW differences were tested among the four groups, and then deeper associations among maternal pre-BMI, GWG, and NBW were investigated by multivariate analysis. NBW increased significantly with the increase of maternal pre-BMI level (P<0.05), except overweight to obesity (P>0.05). The multivariate analysis showed that both pre-BMI and GWG were positively correlated with NBW (P<0.05). Compared with normal pre-BMI, underweight predicted an increased odds ratio of small-for-gestational-age (SGA) and decreased odds ratio for macrosomia and large-for-gestational-age (LGA), and the results were opposite for overweight. With the increase of GWG, the risk of SGA decreased and the risks of macrosomia and LGA increased. In addition, in different pre-BMI categories, the effects of weight gain in the first trimester on NBW were different (P<0.05). NBW is positively affected by both maternal pre-BMI and GWG, extreme pre-BMI and GWG are both associated with increased risks of abnormal birth weight, and maternal pre-BMI may modify the effect of weight gain in each trimester on NBW. A valid GWG guideline for Chinese women is an urgent requirement, whereas existing recommendations seem to be not very suitable for the Chinese. SN - 1862-1783 UR - https://www.unboundmedicine.com/medline/citation/28271662/Effects_of_pre_pregnancy_body_mass_index_and_gestational_weight_gain_on_neonatal_birth_weight_ L2 - http://www.jzus.zju.edu.cn/article.php?doi=10.1631/jzus.B1600204 DB - PRIME DP - Unbound Medicine ER -