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A new flavonoid from Sophora flavescens Ait.
Nat Prod Res. 2017 Oct; 31(19):2228-2232.NP

Abstract

A new flavonoid, 8-(3-hydroxymethyl-2-butenyl)-5,7,2',4'-tetrahydroxyflavanone (1), along with seven known compounds, (2R)-3α,7,4'-Trihydroxy -5-methoxy-8-prenylflavanone (2), (2R)-3β,7,4'- Trihydroxy-5-methoxy-8-prenylflavanone (3), 3,7-dihydroxycoumarin (4), Shandougenines B (5), Specionin (6), Kushenol N (7) and Kushenol I (8) were isolated from the roots of Sophora flavescens. Among them, Compound 5 was isolated from Leguminous plants, and compounds 4 and 6 were isolated from Sophora flavescens for the first time. Their structures were elucidated by the aid of NMR, HRMS, HMBC and CD spectroscopic methods.

Authors+Show Affiliations

a Key Laboratory of Digital Quality Evaluation of Chinese Materia Medica of State Administration of TCM, College of Traditional Chinese Materia Medica , Guangdong Pharmaceutical University , Guangzhou , China.b School of Chinese Medicine , Southern Medical University , Guangzhou , China.a Key Laboratory of Digital Quality Evaluation of Chinese Materia Medica of State Administration of TCM, College of Traditional Chinese Materia Medica , Guangdong Pharmaceutical University , Guangzhou , China.a Key Laboratory of Digital Quality Evaluation of Chinese Materia Medica of State Administration of TCM, College of Traditional Chinese Materia Medica , Guangdong Pharmaceutical University , Guangzhou , China.a Key Laboratory of Digital Quality Evaluation of Chinese Materia Medica of State Administration of TCM, College of Traditional Chinese Materia Medica , Guangdong Pharmaceutical University , Guangzhou , China.c Department of Pharmacy , Hunan University of Medicine , Huaihua , China.a Key Laboratory of Digital Quality Evaluation of Chinese Materia Medica of State Administration of TCM, College of Traditional Chinese Materia Medica , Guangdong Pharmaceutical University , Guangzhou , China.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

28278618

Citation

Huang, Rong, et al. "A New Flavonoid From Sophora Flavescens Ait." Natural Product Research, vol. 31, no. 19, 2017, pp. 2228-2232.
Huang R, Liu Y, Zhao LL, et al. A new flavonoid from Sophora flavescens Ait. Nat Prod Res. 2017;31(19):2228-2232.
Huang, R., Liu, Y., Zhao, L. L., Chen, X. X., Wang, F., Cai, W., & Chen, L. (2017). A new flavonoid from Sophora flavescens Ait. Natural Product Research, 31(19), 2228-2232. https://doi.org/10.1080/14786419.2017.1297992
Huang R, et al. A New Flavonoid From Sophora Flavescens Ait. Nat Prod Res. 2017;31(19):2228-2232. PubMed PMID: 28278618.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A new flavonoid from Sophora flavescens Ait. AU - Huang,Rong, AU - Liu,Yi, AU - Zhao,Lin-Lin, AU - Chen,Xi-Xin, AU - Wang,Feng, AU - Cai,Wei, AU - Chen,Lei, Y1 - 2017/03/06/ PY - 2017/3/11/pubmed PY - 2018/1/3/medline PY - 2017/3/11/entrez KW - Sophora flavescens KW - isolation KW - structural identification SP - 2228 EP - 2232 JF - Natural product research JO - Nat Prod Res VL - 31 IS - 19 N2 - A new flavonoid, 8-(3-hydroxymethyl-2-butenyl)-5,7,2',4'-tetrahydroxyflavanone (1), along with seven known compounds, (2R)-3α,7,4'-Trihydroxy -5-methoxy-8-prenylflavanone (2), (2R)-3β,7,4'- Trihydroxy-5-methoxy-8-prenylflavanone (3), 3,7-dihydroxycoumarin (4), Shandougenines B (5), Specionin (6), Kushenol N (7) and Kushenol I (8) were isolated from the roots of Sophora flavescens. Among them, Compound 5 was isolated from Leguminous plants, and compounds 4 and 6 were isolated from Sophora flavescens for the first time. Their structures were elucidated by the aid of NMR, HRMS, HMBC and CD spectroscopic methods. SN - 1478-6427 UR - https://www.unboundmedicine.com/medline/citation/28278618/A_new_flavonoid_from_Sophora_flavescens_Ait_ L2 - https://www.tandfonline.com/doi/full/10.1080/14786419.2017.1297992 DB - PRIME DP - Unbound Medicine ER -